姓名：张媛 性别：女 职称：副主任医师、副教授 招生院所：附属同仁医院 招生类型：科学与专业学位(硕) 招生专业：耳鼻咽喉科学(硕) 研究方向名称：鼻过敏科学和鼻内镜外科学 电子信箱：summer_zhang1211@126.com


社会任职
1. 2014-2015年度世界过敏组织（WAO）青年委员会共同主席
2. 2016-2017年度世界过敏组织（WAO）鼻-鼻窦炎委员会委员
3. 中华医学会变态反应学分会第六届委员会青年委员会委员
4. 首都医科大学慢性鼻炎和鼻窦炎临床诊疗与研究中心秘书
个人简历
1. 199809-200306:大连医科大学 临床医学专业 本科学习
2. 200309-200607:军医进修学院 耳鼻咽喉科专业 硕士研究生学习
3. 200609-201105:首都医科大学附属北京同仁医院 北京市耳鼻咽喉科研究所 住院医师
4. 200802-200803:加拿大蒙特利尔大学附属Hôtel-Dieu医院 公派学习“鼻腔炎症性疾病的全基因组遗传学相关性研究”
5. 201105-201711:首都医科大学附属北京同仁医院 北京市耳鼻咽喉科研究所 主治医师
6. 201209-201506:首都医科大学 博士研究生学习
7. 201305-201306:比利时根特大学上呼吸道实验室 公派学习“慢性鼻窦炎的甲基化机制”
8. 201812-202004:首都医科大学 副教授
9. 201906-202004:首都医科大学 硕士研究生导师
重要学术论文
1. Liu Z#, Chen J#, Cheng L#, Li H#, Liu S#, Lou H#, Shi J#, Sun Y#, Wang D#, Wang C#, Wang X#, Wei Y#, Wen W#, Yang P#, Yang Q#, Zhang G#, Zhang Y#,, Zhao C#, Zhu D#, Zhu L#, Chen F, Dong Y, Fu Q, Li J, Li Y, Liu C, Liu F, Lu M, Meng Y, Sha J, She W, Shi L, Wang K, Xue J, Yang L, Yin M, et.al.Chinese Society of Allergy and Chinese Society of Otorhinolaryngology-Head and Neck Surgery Guideline for Chronic Rhinosinusitis.. Allergy Asthma Immunol Res. 2020,12(2):176-237.SCI
2. Zhang Y#, Zhang L*.Increasing prevalence of allergic rhinitis in China.. Allergy Asthma Immunol Res. 2019,11(2):156-169.SCI
3. Ren L#, Zhang W, Zhang Y*, Zhang L*.Nasal nitric oxide is correlated with nasal patency and nasal symptoms.. Allergy Asthma Immunol Res. 2019,11(3):367-380.SCI
4. Huang Y#, Wang C#, Xi L, Lou H, Cao F, Li W, Zhang Y*, Zhang L*.Association Between Component-Resolved Diagnosis of House Dust Mite and Efficacy of Allergen Immunotherapy in Allergic Rhinitis Patients.. Clin Transl Allergy. 2019,9:64.SCI
5. Li J#, Jiao J, Gao Y, Zhang Y*, Zhang L*..Association between methylation in nasal epithelial TSLP gene and chronic rhinosinusitis with nasal polyps.. Allergy Asthma Clin Immunol. 2019,15:71.SCI
6. Zhao Y#, Zhang Y*, Wang X, Zhang L*.Variant analysis in Chinese families with hereditary hemorrhagic telangiectasia.. Mol Genet Genomic Med. 2019,7(9):e893.SCI
7. Li J#, Jiao J#, Wang M, Gao Y, Li Y, Wang Y, Zhang Y*, Wang X*, Zhang L*.Hypomethylation of IL8 promoter in nasal epithelial cells of patients with chronic rhinosinusitis with nasal polyps. . J Allergy Clin Immunol . 2019,144(4):993-1003.SCI
8. Zhang Y#, Li Y#, Zhao Y, Wang C*, Zhang L*.Identification of rare variants of allergic rhinitis based on whole genome sequencing and gene expression profiling: A preliminary investigation in four families.. World Allergy Organ J. 2019,12(6):100038.SCI
9. 张媛#，朴颖实，张罗*.IgG4相关性鼻腔鼻窦疾病的研究进展. 中华耳鼻咽喉头颈外科杂志. 2019,54(3):227-231.核心期刊
10. Zhao Y#, Zhao Y, Zhang Y*, Zhang L*.HLA-II genes are associated with outcomes of specific immunotherapy for allergic rhinitis.. Int Forum Allergy Rhinol. 2019,9(11):1311-1317.SCI
11. Zhang Y#, Lan F, Li Y, Wang C*, Zhang L*.Formation of papillary mucosa folds and enhancement of epithelial barrier in odontogenic sinusitis.. Int Forum Allergy Rhinol. 2019,9(11):1281-1288.SCI
12. Piao Y#, Zhang Y#, Yue C, Wang C*, Zhang L*.Immunoglobulin G4-related Chronic Rhinosinusitis: A Pitfall in the Differential Diagnosis of Granulomatosis with Polyangiitis, Rosai-Dorfman Disease and Fungal Rhinosinusitis. Hum Pathol. 2018,73(3):82-88.SCI
13. Huang Y#, Zhang Y*, Zhang L*.Prevalence of allergic and nonallergic rhinitis in a rural area of northern China based on sensitization to specific aeroallergens. Allergy Asthma Clin Immunol. 2018,14:77.SCI
14. Cheng L#, Chen J#, Fu Q#, He S#, Li H#, Liu Z#, Tan G#, Tao Z#, Wang D#, Wen W#, Xu R#, Xu Y#, Yang Q#, Zhang C#, Zhang G#, Zhang R#, Zhang Y#, Zhou B#, Zhu D#, Chen L, Cui X, Deng Y, Guo Z, Huang Z, Huang Z, Li H, Li J, Li W, Li Y, Xi L, Lou H, Lu M, Ouyang Y, Shi W, Tao X, Tian H, et.al.Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis. Allergy Asthma Immunol Res. 2018,10(4):300-353.SCI
15. Ren L#, Zhang L, Duan S, Zhang W, Zhang Y*.Nasal airflow resistance measured by rhinomanometry in a healthy population of China. Int Forum Allergy Rhinol. 2018,8(11):1308-1314.SCI
16. Zhang X#, Lan F, Zhang Y*, Zhang L*.Chinese Herbal Medicine to Treat Allergic Rhinitis: Evidence From a Meta-Analysis.. Allergy Asthma Immunol Res. 2018,10(1):34-42.SCI
17. 36.Zhang Y#, Gevaert E, Lou H, Wang X, Zhang L*, Bachert C*, Zhang N.Chronic rhinosinusitis in Asia. J Allergy Clin Immunol. 2017,140(5):1196-1203.SCI
18. Bao Y#, Chen J#, Cheng L#, Guo Y#, Hong S#, Kong W#, Lai H#, Li H#, Li H#, Li J#, Li T#, Lin X#, Liu S#, Liu Z#, Lou H#, Meng J#, Qiu Q#, Shen K#, Tang W#, Tao Z#, Wang C#, Wang X#, Wei Q#, Xiang L#, Xie H#, Xu Y#, Zhang G#, Zhang Y#, Zheng Y#, Zhi Y#, Chen D, Hong H, Li Q, Liu L, et.al.Chinese Society of Allergy (CSA) and Chinese Allergic Rhinitis Collaborative Research Group (C2AR2G). Chinese Guideline on allergen immunotherapy for allergic rhinitis. J Thorac Dis. 2017,9(11):4607-4650.SCI
19. Zhao Y#, Zhang Y*, Zhang L*.Variant of PBX2 gene in the 6p21.3 asthma susceptibility locus is associated with allergic rhinitis in Chinese subjects.. Int Forum Allergy Rhinol. 2016,6(5):537-543.SCI
20. Li J#, Zhang Y#, Lin X, Ruan Y, Wang C*, Zhang L*.Association between DNA hypomethylation at IL13 gene and allergic rhinitis in house dust mite-sensitized subjects. . Clinical & Experimental Allergy. 2016,46(2):298-307.SCI
21. Xi L#, Cao F, Zhang Y*, Zhang L*.Severity of nasal obstruction can predict the anxiety status of patients with allergic rhinitis but not patients with vasomotor rhinitis.. Int Forum Allergy Rhinol. 2016,6(11):1196-1203.SCI
22. Zhao Y#, Zhao Y, Li J, Zhang Y*, Zhang L*.HLA-DRB1*08:03:02 and HLA-DQB1*06:01:01 are associated with house dust mite-sensitive allergic rhinitis in Chinese subjects. Int Forum Allergy Rhinol. 2016,6(8):854-861.SCI
23. Li J#, Zhang Y#, Zhang L*.Discovering susceptibility genes for allergic rhinitis and allergy using a genome-wide association study strategy.. Curr Opin Allergy Clin Immunol. 2015,15(1):33-40.SCI
24. Zhang Y#, Li J, Wang C*, Zhang L*.Association between the interaction of key genes involved in effector T-cell pathways and susceptibility to develop allergic rhinitis: A population-based case-control association study. PloS one. 2015,10(7):e**-e**.SCI
25. Zhang Y#, Zhang L*.Prevalence of allergic rhinitis in China.. Allergy Asthma Immunol Res. 2014,6(2):105-113.SCI
26. Pérez-Novo CA#*, Zhang Y#, Denil S, Trooskens G, De Meyer T, Van Criekinge W, Van Cauwenberge P, Zhang L, Bachert C.Staphylococcal enterotoxin B influences the DNA methylation pattern in nasal polyp tissue: a preliminary study.. Allergy Asthma Clin Immunol . 2013,9(1):48.SCI
27. Wei X#, Zhang Y#, Fu Z, Zhang L*. The association between polymorphisms in the MRPL4 and TNF-α genes and susceptibility to allergic rhinitis.. PLoS ONE. 2013,8 (3):e57981.SCI
28. Zhang Y#, Wang X#, Zhang W, Han D, Zhang L*, Bachert C.Polymorphisms in thymic stromal lymphopoietin gene demonstrate a gender and nasal polyposis-dependent association with chronic rhinosinusitis.. Human Immunology. 2013,74(2):241-248.SCI
29. Zhang Y#, Wang C, Zhao Y, Zhang L*.Some polymorphisms in EBV-induced gene 3 modify the risk for chronic rhinosinusitis.. Am J Rhinol & Allergy. 2013,27 (2):91-97.SCI
30. Zhang Y#, Duan S#, Wei X#, Zhao Y, Zhao L, Zhang L*.Association between polymorphisms in FOXP3 and EBI3 genes and the risk for development of allergic rhinitis in Chinese subjects.. Hum Immunol. 2012,73(9):939-945.SCI
31. 张媛#，锡琳，赵延明，段甦，赵丽萍，张罗*.白细胞介素1受体相关激酶4基因单核苷酸多态性与变应性鼻炎的相关性. 中华耳鼻咽喉头颈外科杂志. 2012,47(6):476-480.核心期刊
32. Zhang Y#, Song X#, Zhao Y, Zhang L*, Bachert C..Single nucleotide polymorphisms in thymistromal lymphopoietin gene are not associated with allergic rhinitis susceptibility in Chinese subjects.. BMC Med Genet. 2012,13:79.SCI
33. Zhang Y#, Endam LM, Filali-Mouhim A, Zhao L, Desrosiers M, Han D, Zhang L*.Polymorphisms in RYBP and AOAH genes are associated with chronic rhinosinusitis in a Chinese population: A replication study.. PLoS ONE. 2012,7(6):e39247.SCI
34. Xi L#, Zhang Y#, Han D, Zhang L*.Effect of asthma, aeroallergen category and gender on the psychological status of patients with allergic rhinitis.. J Investig Allergol Clin Immunol. 2012,22(4):264-269.SCI
35. 张媛#，张罗*.变应性疾病的遗传学研究. 临床耳鼻咽喉头颈外科杂志. 2012,26(17):809-813.核心期刊
36. 张媛#, 赵延明, 段甦, 赵丽萍, 张罗*.FCER1A基因单核苷酸多态性与变应性鼻炎血清总IgE含量的相关性分析. 中华耳鼻咽喉头颈外科杂志. 2012,47(4):289-293.核心期刊
37. 张媛#，刘承耀，段甦，赵延明，张罗*.过敏性鼻炎皮肤点刺试验阳性界值对血清特异性IgE诊断价值的影响. 首都医科大学学报. 2011,32(6):717-720.核心期刊
38. Han D#, Liu S#, Zhang Y#, Wang J, Wang D, Kong W, Wang S, Cheng L, Zhang L*.Efficacy and safety of fluticasone furoate nasal spray for 2 weeks in Chinese adult and adolescent subjects with intermittent or persistent allergic rhinitis.. Allergy Asthma Proc . 2011,32(6):472-487.SCI
39. Zhang Y#, Lin X, Desrosiers M, Zhang W, Meng N, Zhao L, Han D, Zhang L*.Association Pattern of Interleukin-1 Receptor-Associated Kinase-4 Gene Polymorphisms with Allergic Rhinitis in a Han Chinese Population. PLoS ONE. 2011,6(6):e21769..SCI
40. 张媛#，赵延明，贺飞，张罗*.儿童过敏性鼻炎的吸入性过敏原. 首都医科大学学报. 2011,32(1):13-16.核心期刊
41. Zhang Y#, Liu C, Han D, Zhang L*.Correlation of routine examinations for the diagnosis of house dust mite allergic rhinitis. ORL J Otorhinolaryngol Relat Spec.. 2011,73(4):182-188.SSCI
42. Zhang Y#, Endam LM, Filali-Mouhim A, Bossé Y, Castano R, Desrosiers M*.Polymorphisms in the nitric oxide synthase 1 gene are associated with severe chronic rhinosinusitis. Am J Rhinol & Allergy. 2011,25(2):e49-54.SCI
43. 张媛#，王成硕，张罗*.FOXP3基因多态性与过敏性鼻炎的相关性研究. 中华耳鼻咽喉头颈外科杂志. 2010,45(5):397-400.核心期刊
44. Zhang Y#, Duan S#, Lin X, Zhang W, Meng N, Zhao L, Zhao Y, Han D*, Zhang L*.SNPs in the FCER1A Gene Region Show No Association with Allergic Rhinitis in a Han Chinese Population. PLoS One. 2010,5(12):e15792.SCI
45. Zhang Y#, Zhai SQ#, Shou JY, Song W, Sun JH, Guo W, Zheng GL, Hu YY, Gao WQ*.Isolation, growth and differentiation of hair cell progenitors from the newborn rat cochlear greater epithelial ridge. J NEUROSCI METH. 2007,164(2):271-279.SCI
主编或副主编的著作/译著
重要奖项
1. 慢性鼻窦炎发病机制及关键诊疗技术的创新与应用 北京市科学技术奖 一等奖 201912
2. 过敏性鼻炎治疗技术的创新与应用 北京市科技进步奖 一等奖 201612
3. 慢性鼻窦炎免疫机制和诊疗技术的研究与应用 北京市科学技术奖 二等奖 201611