姓名：陈煜 性别：男 职称：主任医师、教授 招生院所：北京佑安医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：内科学（传染病）(博) 内科学（传染病）(硕) 研究方向名称：重型肝炎基础与临床研究 电子信箱：chybeyond@sohu.com


社会任职
1. 中华医学会肝病学分会第八届委员会副秘书长
2. 中华医学会肝病学分会第七届委员会青年委员会副主任委员
3. 中华医学会肝病学分会第七届委员会重型肝病与人工肝学组副组长
4. 中国医师协会急救复苏专业委员会第三届委员会委员
5. 中国重症血液净化协作组第一届委员会副主任委员
6. 全国重型肝病及人工肝血液净化攻关协作组副组长
7. 中国研究型医院学会肝病专业委员会重症肝病学组副组长
8. 中国医药教育协会肝病专业委员会常委
9. 疑难及重症肝病攻关协作组副组长
10. 北京医药科学技术发展协会肝病事业部主任
11. 北京亚太肝病诊疗技术联盟北京联盟副理事长
12. 北京医学会肝病学分会第七届委员会重型肝病与人工肝学组副组长
13. 北京医院协会医疗管理科学专业委员会委员
14. 吴阶平医学基金会肝病医学部肝功能评估方法研究基金专家委员会委员
个人简历
1. 199108-199607:新乡医学院 本科
2. 199608-199907:山东医科大学 硕士
3. 199908-200207:首都医科大学 博士
4. 200208-200308:首都医科大学附属北京佑安医院 主治医师
5. 200309-200907:首都医科大学附属北京佑安医院 副主任医师
6. 200309-200401:香港大学医学院 访问
7. 200709-200712:英国伦敦大学医学院 访问
8. 200908-:首都医科大学附属北京佑安医院 主任医师
重要学术论文
1. Bi Y, Li J, Yang Y, Wang Q, Wang Q, Zhang X, Dong G, Wang Y, Duan Z, Shu Z, Liu T, Chen Y*, Zhang K*, Hong F*..Human liver stem cells attenuate concanavalin A-induced acute liver injury by modulating myeloid-derived suppressor cells and CD4+ T cells in mice. Stem Cell Res Ther. 2019,10(1):22.SCI
2. Xing Liu，Ming Kong，Xin Hua，Yinchuan Yang，Manman Xu，Yanzhen Bi，Lu Li，Zhongping Duan，Yu Chen*.Effects of an individualized nutrition intervention on the respiratory quotient of patients with liver failure. Asia Pac J Clin Nutr. 2019,28（3）:428-434.SCI
3. Luo Lei,Zou Huaibin,Zheng Suju,Duan Zhongping,Chen Yu.Letter to the Editor: Suggestions for Rational Management of Nonalcoholic Fatty Liver Disease. Hepatology. 2019,70(4):1492-1493.SCI
4. Jia Yao，Shuang Li，Li Zhou，Lei Luo，Lili Yuan，ZhongpingDuan，Jun Xu*,Yu Chen*.Therapeutic effect of double plasma molecular adsorption system and sequential half-dose plasma exchange in patients with HBV-related acute-on-chronic liver failure. J Clin Apher. 2019,34(4):392-398.SCI
5. Sarin Shiv Kumar,Choudhury Ashok,SharmaManoj K,Maiwall Rakhi,Al Mahtab Mamun, RahmanSalimur,Ning Q,Chen Tao,Ma Ke,Duan Z,Yu Chen,et al..Acute-on-chronic liver failure: consensus recommendations ofthe Asian Pacific association for the study of the liver (APASL): an update. Hepatol Int. 2019,13(6):826-828.SCI
6. Yanzhen Bi, Xiyu Liu, Chuanping Si, Ye Hong, Yongke Lu, Pengfei Gao,Yonghong Yang， Xiaobei Zhang, Yibo Wang, Huabao Xiong, Zhongping Duan, Yu Chen*,Feng Hong*.Transplanted adult human hepatic stem/progenitor cells prevent histogenesis of advanced hepatic fibrosis in mice induced by carbon tetrachloride. Am J Transl Res. 2019,11(4):2350-2358.SCI
7. Shanshan Li,Yanzhen Bi, Quanquan Wang, ManmanXu, ZhenglaiMa, YonghongYang, Yongkai Chang, Suling Chen,Derong Liu, Zhongping Duan, Feng Hong*,Yu Chen*.Transplanted mouse liver stem cells at different stages of differentiation ameliorate concanavalin A-induced acute liver injury by modulating Tregs and Th17 cells in mice. American Journal Of Translational Research. 2019,11(12):7324-7337.SCI
8. Yao J#, Zhou X Kong M, Li L, Hua X, Zhao Y, Yu S, Chen Y, Duan Z*..Effects of eating frequency on respiratory quotient in patients with liver cirrhosis: a randomized controlled trial. Asia Pac J Clin Nutr. 2018,27（2）:322-328.SCI
9. Bai L, Fu L, Li L, Ren F, Zheng Q, Liu S, Han Y, Zheng S*, Chen Y*, Duan Z*..Cellular Mechanisms of Hepatoprotection Mediated by M2-Like Macrophages. Medical science monitor. 2018,24:2675-2682.SCI
10. Yao J, Zhou X, Wang H, Yuan L, Chen Y*, Duan Z*..Persistently Increased Resting Energy Expenditure Predicts Short-Term Mortality in Patients with Acute-on-Chronic Liver Failure. Annals of nutrition and metabolism. 2018,73(1):2-9.SCI
11. Wu T, Li J, Shao L, Xin J, Jiang L, Zhou Q, Shi D, Jiang J, Sun S, Jin L, Ye P, Yang L, Lu Y, Li T, Huang J, Xu X, Chen J, Hao S, Chen Y, Xin S, Gao Z, Duan Z, Han T, Wang Y, Gan J, Feng T, Pan C, Chen Y, Li H, Huang Y, Xie Q, Lin S, Li L, Li J; Chinese Group on the Study of Severe Hepatitis B (COSS.Development of diagnostic criteria and a prognostic score for hepatitis B virus-related acute-on-chronic liver failure. Gut. 2018,67(12):2181-2191.SCI
12. Bai L, Jin W, Kong M, Zhang X, Zheng S, Chen Y, Li L, Liu H, Zhu L, Ren F, Li J, Han Y, Duan Z.Injury Resistance in the Setting of Liver Fibrosis Is Accompanied by the Inhibition of High-Mobility Group Box-1 Translocation and Release. Dig Dis. 2018,36(2):167-176.
13. Anand L, Choudhury A, Bihari C, Sharma BC, Kumar M, Maiwall R, Siam Tan S, Shah SR, Hamid S, Butt AS, Jafri W, Chawla YK, Taneja S, Duseja A, Dhiman RK, Mahtab MA, Ghazinyan H, Duan Z, Chen Y, Shukla A, Hu J, Abbas Z, Treeprasertsuk S, Lesmana LA, Lesmana CR, Sollano JD, Carpio G, Sahu MK, Kumar G, .Flare of Autoimmune Hepatitis Causing Acute on Chronic Liver Failure: Diagnosis and Response to Corticosteroid Therapy. Hepatology. 2018,DOI:10.1002/hep.30205.SCI
14. Gao S, Duan ZP, Chen Y, van der Meer F, Lee SS, Osiowy C, van Marle G, Coffin CS.Compartmental HBV evolution and replication in liver and extrahepatic sites after nucleos/tide analogue therapy in chronic hepatitis B carriers. J Clin Virol. 2017,94:8-14.SCI
15. Bai L, Liu X, Zheng Q, Kong M, Zhang X, Hu R, Lou J, Ren F, Chen Y, Zheng S, Liu S, Han YP, Duan Z, Pandol SJ.M2-like macrophages in the fibrotic liver protect mice against lethal insults through conferring apoptosis resistance to hepatocytes. Sci Rep. 2017,7(1):10518.SCI
16. Bian DD, Zhou HY, Liu S, Liu M, Duan C, Zhang JY, Jiang YY, Wang T, Chen Y, Wang Z, Zheng SJ, Duan ZP.Current treatment status and barriers for patients with chronic HCV infection in mainland China: A national multicenter cross-sectional survey in 56 hospitals. Medicine . 2017,96(34):e7885.SCI
17. Shi HB, Lou JL, Shi HL, Ren F, Chen Y, Duan ZP..Construction of Gpm6a/ReelinGFPCreERT2 by BAC recombination using a specific gene in hepatic mesothelial or stellate cells. World J Gastroenterol. 2017,23(2):224-231.SCI
18. Li JF, Zheng SJ, Wang LL, Liu S, Ren F, Chen Y, Bai L, Liu M, Duan ZP.Glucosylceramide synthase regulates the proliferation and apoptosis of liver cells in vitro by Bcl‑2/Bax pathway. Mol Med Rep. 2017,16(5):7355-7360.SCI
19. Zheng Q, Bai L, Zheng S, Liu M, Zhang J, Wang T, Xu Z, Chen Y, Li J, Duan Z.Efficient inhibition of duck hepatitis B virus DNA by the CRISPR/Cas9 system. Mol Med Rep. 2017,16(5):7199-7204.SCI
20. Zhang X, Lou J, Bai L, Chen Y, Zheng S, Duan Z.Immune Regulation of Intrahepatic Regulatory T Cells in Fibrotic Livers of Mice. Med Sci Monit. 2017,23:1009-1016.SCI
21. 李璐，陈煜*.肝衰竭患者的营养评估及营养干预研究进展. 中华肝脏病杂志. 2017,25（7）:548-552.核心期刊
22. Shi H#, Han W, Shi H, Ren F, Chen D, Chen Y*,Duan Z*..Augmenter of liver regeneration protects against carbon tetrachloride-induced liver injury by promoting autophagy in mice. Oncotarget. 2017,8(8):12637-12648.SCI
23. Hongbo Shi#, Honglin Shi , Feng Ren , Dexi Chen , Yu Chen *,Zhongping Duan*..Naringin in Ganshuang Granule suppresses activation of hepatic stellate cells for anti-fibrosis effect by inhibition of mammalian target of rapamycin. J Cell Mol Med. 2017,21（3）:500-509.SCI
24. 韩伟佳, 时红波, 时红林, 宋金玥, 任锋, 段钟平, 陈煜*. .肝再生增强因子通过增加自噬水平促进CCl4诱导的急性肝损伤中HL-7702细胞的增殖. 中华肝脏病杂志. 2016,24(10):761-766.核心期刊
25. Cheng XP, Zhao J, Chen Y, Meng FK, Xu B, Yu HW, Meng QH, Liu YM, Zhang SB, Meng S, Zhang JY, Zhang JY, Duan ZP, Zheng SJ.Comparison of the ability of the PDD-ICG clearance test, CTP, MELD, and MELD-Na to predict short-term and medium-term mortality in patients with decompensated hepatitis B cirrhosis. Eur J Gastroenterol Hepatol. 2016,28(4):444-448.SCI
26. Shi HB, Sun HQ, Shi HL, Ren F, Chen Y, Chen DX, Lou JL, Duan ZP.Autophagy in anti-apoptotic effect of augmenter of liver regeneration in HepG2 cells. World J Gastroenterol. 2015,21(17):5250-8.SCI
27. Li JF, Qu F, Zheng SJ, Ren F, Wu HL, Liu M, Ren JY, Chen Y, Duan ZP, Zhang JL.Plasma sphingolipids: potential biomarkers for severe hepatic fibrosis in chronic hepatitis C. Mol Med Rep. 2015,12(1):323-30.SCI
28. Su-Jun Zheng, Shuang Liu, Mei Liu, Malcolm A McCrae, Jun-Feng Li, Yuan-Ping Han, Chun-Hui Xu, Feng Ren, Yu Chen*, Zhong-Ping Duan*..Prognostic Value of M30/M65 for Outcome in HBV Related Acute-on-Chronic Liver Failure. World Journal of Gastroenterology. 2014,20(9):2403-2411.SCI
29. Mei Liu, Su-Jun Zheng,Weihong Xu, Jianying Zhang, Yu Chen*,Zhongping Duan*..Changing Interdigestive Migrating Motor Complex in Rats under Acute Liver Injury. BioMed Research International. 2014,2014:634281.SCI
30. Lu Li, Yi-Rong Liu, Shan Gao, Jun-Feng Li, Shan-Shan Li, Dan-Dan Zhang, Shuang Liu, Li Bai, Su-Jun Zheng,Zhong-Ping Duan, Min Qi, and Yu Chen*.Inhibition of 5-Lipoxygenase Pathway Attenuates Acute Liver Failure by Inhibiting Macrophage Activation. Journal of Immunology Research. 2014,2014:697560.SCI
31. Ming Kong, Shufen Tian, Jun Zhao, Mei Ding, Xia Feng, Zhongping Duan, Yu Chen*.The effect of alpha-fetoprotein on the activation and phagocytosis of granulocytes and monocytes. Hepato-Gastroenterology. 2012,59（120）:2385-23888.SCI
32. Shi HongBo#, Chen Yu#, Kong Ming, Shi HongLin, Han Yuan Ping and Duan Zhong Ping.Augmenter of Liver Regeneration may be a Candidate for Prognosis of HBV Related Acute-on-Chronic Liver Failure as a Regenerative Marker. Hepato-Gastroenterology. 2012,29（118）:1933-1938.SCI
33. Huaibin Zou, Yu Chen*, Zhongping Duan*，Hua Zhang.Protective Effect of Hepatitis B Vaccine Combined with Two-Dose Hepatitis B Immunoglobulin on Infants Born to HBsAg-Positive Mothers. PLOS One. 2011,6（10）:e26748.SCI
34. Huaibin Zou, Yu Chen, Zhongping Duan, Hua Zhang，Calvin Pan.Virologic Factors Associated with Failure to Passive-Active Immunoprophylaxis in Infants Born to HBsAg-Positive Mothers. Journal of viral hepatitis. 2011,19(2):1365-2893.SCI
35. 刘义荣，范作鹏，杨薇，高原，陈煜*.吲哚菁绿滞留测试对肝储备功能的评价. 中华肝脏病杂志. 2010,18（6）:476-477.核心期刊
36. F.Ren#, Y.chen#，Y.Wang, Y.Yan, J.Zhao, M.Ding, J.Zhang, Y.Jiang, Y.Zhai, Z.Duan.Comparative serum proteomic analysis of patients with acute-on-chronic liver failure: Alpha-1-acid glycoprotein maybe a candidate marker for prognosis of hepatitis B virus infection. Journal of viral hepatitis. 2010,10：:816-824.SCI
37. 陈煜, 李文, 李卫红, 张海燕, 丁美, 任锋, 安威, 段钟平. .过表达CCAAT增强子结合蛋白α对HepG2细胞代谢能力的影响. 中华肝脏病杂志. 2010,18(6):474-475.核心期刊
38. 康玮玮，周莉，刘旭华，赵军，陈煜*.肝硬化患者吲哚菁绿清除试验的临床评价. 中华消化外科杂志. 2009,8（4）:300-301.核心期刊
39. 陈煜,魏琳琳,闫丽,赵军,段钟平.C3A永生化肝细胞系的部分功能评价. 中华肝脏病杂志. 2007,15(10):787-788.核心期刊
40. 陈煜,赵丽莉,高虹,尤红,唐淑珍,韩大康,段钟平.慢性重型肝炎肝衰竭患者血浆对C3A细胞增殖和生物转化功能的影响. 中华肝脏病杂志. 2006,14(1):63-65.核心期刊
41. 陈煜,段钟平,韩大康,赵军,李颖,杨建昆.重型肝炎人工肝血浆置换肝素应用的实时监测. 中华肝脏病杂志. 2005,13(6):465-466.核心期刊
42. 陈煜,段钟平,王宝恩,贾继东,陈光勇,李亿梅.过渡型CK19阳性表达细胞的研究. 中华肝脏病杂志. 2004,12(1):38-39.核心期刊
主编或副主编的著作/译著
1. 《全国肝病科普咨询专家规范化培训试题》,主编,中国医药科技出版社,201406
重要奖项
1. 北京优秀医师奖 2018年度北京优秀医师奖 - 201808
2. 提高肝移植救治肝衰竭疗效的关键技术集成创新 中华医学科技奖 三等奖 201711
3. 提高肝移植救治肝衰竭疗效的关键技术集成创新 北京市科学技术奖 三等奖 201711
4. 国之名医 青年新锐 - 201709
5. 2015首都十大医生 2015首都十大医生 - 201508
6. 重型肝炎血清肝纤维化指标的动态变化、预后评价及其蛋白组学研究 王宝恩肝纤维化研究基金科研成果奖 - 201208
7. 北京市病毒性肝炎临床诊断及治疗的一体化研究 2007年度北京市科技进步 一等奖 200812
8. 病毒性肝炎规范化诊断及治疗的关键技术研究 2008年度中华医学科技 二等奖 200812
9. 中国重型肝炎人工肝临床治疗适应症研究 北京市科学技术奖 三等奖 200504