姓名：谢正德 性别：男 职称：研究员、教授 招生院所：附属儿童医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：儿内科学(博) 儿内科学(硕) 研究方向名称：儿科常见病毒感染病原学及EB病毒感染相关疾病 电子信箱：xiezhengde@bch.com.cn


社会任职
1. 《病毒学报》杂志第六届编委会
2. 中国研究型医院学会儿科专业委员会常务委员
3. 《中华实验和临床病毒学杂志》编委
4. 中华医学会儿科学分会医院感染控制专业委员会 副主任委员
5. 中国医疗保健国际交流促进会分子诊断学分会 副主任委员
6. 《国际流行病学传染病学杂志》第三届通讯编委
7. 中华预防医学会流感预防控制工作委员会 委员
8. 中华医学会儿科学分会感染学组副组长
9. 中华医学会医学病毒学分会临床病毒学组副组长
10. 中国研究型医院学会病毒肿瘤学科专业委员会常务委员
11. 国家卫健委传染病标准委员会委员
12. 中国医促会分子诊断学分会儿科感染学部主任
13. 国家卫健委疾病预防控制专家委员会委员
14. 中国中药协会儿童健康与药物研究专业委员会 感染学组组长
15. 中国中药协会儿童健康与药物研究专业委员会 常委
个人简历
1. 198609-199107:华中科技大学附属同济医学院 学习
2. 199107-200203:首都医科大学宣武医院 任职
3. 200203-201805:首都医科大学附属北京儿童医院 任职
重要学术论文
1. Chen X﹟, Ji T﹟, Guo J, Wang W, Xu W＊, Xie Z＊..Molecular Epidemiology of Echovirus 18 Circulating in Mainland China from 2015 to 2016. . Virol Sin. 2019,34(1):50-58.SCI
2. 段亚丽,朱云,徐保平,李昌崇,陈爱欢,邓力,鲍一笑,曹玲,孙云,宁丽敏,符州,刘春艳,殷菊,申昆玲,周云连＊,谢正德＊..儿童社区获得性肺炎中人腺病毒感染的多中心研究.. 中华儿科杂志. 2019,57(1):27-32..核心期刊
3. Zhao X﹟, Zhang G﹟, Liu S﹟, Chen X﹟, Peng R, Dai L, Qu X, Li S, Song H, Gao Z, Yuan P, Liu Z, Li C, Shang Z, Li Y, Zhang M, Qi J, Wang H, Du N, Wu Y, Bi Y, Gao S, Shi Y, Yan J, Zhang Y, Xie Z＊, Wei W＊, Gao GF＊.. Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B. Cell. 2019,177(6):1553-1565..SCI
4. 艾军红, 谢正德＊.儿童呼吸道病毒感染的实验室诊断方法及合理应用.. 中国实用儿科杂志. 2019,34（2）:103-107..核心期刊
5. 刘军，谢正德*.毛细支气管炎的病原学及临床流行病学特征. 中国实用儿科杂志. 2019,25（9）:729-732.核心期刊
6. Yu J﹟, Liu C﹟, Xiao Y﹟, Xiang Z, Zhou H, Chen L, Shen K, Xie Z＊, Ren L＊, Wang J＊..Respiratory Syncytial Virus Seasonality, Beijing, China, 2007-2015.. Emerg Infect Dis.. 2019,25(6):1127-1135..SCI
7. 秦强，谢正德*.慢性活动性EBV感染的诊治进展. 传染病信息. 2019,32（2）:175-180.核心期刊
8. Zhengde Xie*, Xiangpeng Chen.Concerning the discovery of mechanism for enterovirus B infection published in Cell. Pediatric Investigation. 2019,3(3):194-195.
9. 王巍, 谢正德*.病毒感染激活和抑制炎症小体的研究进展.. 病毒学报. 2019,35（3）:557-564.核心期刊
10. Ai J, Xie Z*.Epstein-Barr Virus-Positive T/NK-Cell Lymphoproliferative Diseases in Chinese Mainland. . Front. Pediatr. 2018,6:289.SCI
11. 陈祥鹏#, 郭佳运#, 李静洁, 王巍, 孙素真*, 谢正德*..河北省儿童病毒性脑炎及脑膜炎埃可病毒30型VP1基因特征分析.. 病毒学报. 2018,34（2）:165-171.核心期刊
12. Yun Zhu #, Changchong Li #, Li Chen #, Baoping Xu #, Yunlian Zhou, Ling Cao, Yunxiao Shang, Zhou Fu, Aihuan Chen, Li Deng, Yixiao Bao, Yun Sun, Limin Ning, Chunyan Liu, Ju Yin, Zhengde Xie*, Kunling Shen*.A novel human coronavirus OC43 genotype detected in mainland China. Emerg Microbes Infect. 2018,7（1）:173.SCI
13. 段亚丽, 谢正德*.我国呼吸道感染人腺病毒的基因型流行概况. 中华实验和临床病毒学杂志. 2018,32(4):430-434.核心期刊
14. Xu L#, Jiang X#, Zhu Y, Duan Y, Huang T, Huang Z, Liu C, Xu B, Xie Z*.A Multiplex Asymmetric Reverse Transcription-PCR Assay Combined With an Electrochemical DNA Sensor for Simultaneously Detecting and Subtyping Influenza A Viruses. Front Microbiol. 2018,9:1405.SCI
15. Xu L #, Gao H #, Zeng J, Liu J, Lu C, Guan X, Qian S*, Xie Z*.A fatal case associated with respiratory syncytial virus infection in a young child. BMC Infect Dis. 2018,18(1):217.SCI
16. Xu C, Ai J, Zhang Q, Li T, Wu X, Xie Z*, Duan Z*.An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection.. J. Vis. Exp.. 2018,133：e56515:1-7.SCI
17. Xu L#, Liu J#, Liu C, Duan Y, Zhu Y, Xu B*, Xie Z*..Case-control study of the epidemiological and clinical features of human adenovirus 55 and human adenovirus 7 infection in children with acute lower respiratory tract infections in Beijing, China, 2008-2013.. BMC Infect Dis. 2018,18(1):634.SCI
18. Chen X﹟, Xu B﹟, Guo J﹟, Li C, An S, Zhou Y, Chen A, Deng L, Fu Z, Zhu Y, Liu C, Xu L, Wang W, Shen K*, Xie Z*. Genetic variations in the fusion protein of respiratory syncytial virus isolated from children hospitalized with community-acquired pneumonia in China. Sci Rep.. 2018,8(1):4491.SCI
19. Yu J﹟, Xie Z﹟, Zhang T﹟, Lu Y﹟, Fan H﹟, Yang D﹟, Bénet T, Vanhems P, Shen K, Huang F, Han J, Li T, Gao Z, Ren L*, Wang J*.Comparison of the prevalence of respiratory viruses in patients with acute respiratory infections at different hospital settings in North China, 2012-2015.. BMC Infect Dis. 2018,18(1):72.SCI
20. Zhang C#, Xiu L#, Xiao Y, Xie Z*, Ren L*, Peng J*..Simultaneous Detection of Key Bacterial Pathogens Related to Pneumonia and Meningitis Using Multiplex PCR Coupled With Mass Spectrometry. Front Cell Infect Microbiol. 2018,8:107.SCI
21. Xiangpeng Chen#, Jiayun Guo#, Jingjie Li#,　Qiuping Li,　Junhong Ai,　Suzhen Sun*,　Zhengde Xie*..Serotypes of human enteroviruses causing pediatric viral encephalitis and meningitis in Hebei province, China, from 2013 to 2015.. Pediatr Invest. 2018, 2(2):98-104.
22. Xu L, Zhu Y, Ren L, Xu B, Liu C, Xie Z*, Shen K*..Characterization of the Nasopharyngeal Viral Microbiome from Children with Community-Acquired Pneumonia but Negative for Luminex xTAG Respiratory Viral Panel Assay Detection. J Med Virol. 2017,doi: 10.1002/jmv.24895:doi: 10.1002/jmv.24895.SCI
23. Song J, Zhang Y, Wang H, Shi J, Sun L, Zhang X, Yang Z, Guan W, Zhang H, Yu P, Xie Z, Cui A, Ng TI, Xu W..Emergence of ON1 genotype of human respiratory syncytial virus subgroup A in China between 2011 and 2015. Sci Rep. 2017,7(1):5501.SCI
24. Ai J, Xie Z*, Liu G, Chen Z, Yang Y, Li Y, Chen J, Zheng G, Shen K*. .Etiology and prognosis of acute viral encephalitis and meningitis in Chinese children: a multicentre prospective study. BMC Infect Dis. 2017,17(1):494.SCI
25. 刘晓红, 谢正德, 任丽丽, 刘春艳, 徐保平, 杨燕,钱素云, 申昆玲..儿童急性下呼吸道人博卡病毒感染及临床特征的比较研究. 中国病毒病杂志. 2017,7（5）:350-355..核心期刊
26. 陈丽, 谢正德*..白细胞介素-10与EB病毒相关疾病的关系研究进展. 中华实用儿科临床杂志. 2017,32（10）:791-793..核心期刊
27. Song J, Zhang Y, Wang H, Shi J, Sun L, Zhang X, Yang Z, Guan W, Zhang H, Yu P, Xie Z, Cui A, Ng TI, Xu W..Emergence of ON1 genotype of human respiratory syncytial virus subgroup A in China between 2011 and 2015. Sci Rep.. 2017,7(1):5501..SCI
28. Wang J#, Yu P#, Xie Z#, Yan T, Chen C, Shen X, Chen X, Li L, Wang X, Sun S, Ma X..A resequencing pathogen microarray method for high-throughput molecular diagnosis of multiple etiologies associated with central nervous system infection. Arch Virol.. 2017,162(12):3769-3778..SCI
29. Chen X, Li J, Guo J, Xu W, Sun S*, Xie Z*..An outbreak of echovirus 18 encephalitis/meningitis in children in Hebei Province, China, 2015. Emerg Microbes Infect.. 2017,6(6):e54.SCI
30. 陈丽, 朱云, 谢正德, 徐保平, 李昌崇, 曹玲, 尚云晓, 符州, 周云连, 鲍一笑, 邓力, 陈爱欢, 刘春艳, 殷菊, 申昆玲..儿童社区获得性肺炎中人冠状病毒感染的多中心研究. 中国病毒病杂志. 2017,7（3）:201-206..核心期刊
31. 黄志卓, 张乐萍, 谢正德*..EB病毒感染相关疾病的基因缺陷研究进展. 中华实用儿科临床杂志. 2016,31(22):1696-1699..核心期刊
32. 艾军红, 谢正德*, 申昆玲. .EB病毒及儿童EB病毒相关疾病. 中华实用儿科临床杂志. 2016,31(22):1683-1686.核心期刊
33. Wang Y, Li Y, Lu R, Zhao Y, Xie Z, Shen J, Tan W*.Phylogenetic evidence for intratypic recombinant events in a novel human adenovirus C that causes severe acute respiratory infection in children. Sci Rep.. 2016,6:23014.SCI
34. 刘晓红，谢正德*..儿童急性呼吸道多病原体混合感染的研究进展. 国际流行病学传染病学杂志. 2016,43（1）:51-53..核心期刊
35. 刘春艳, 谢正德*..EB病毒感染相关疾病的实验室诊断. 中华实用儿科临床杂志. 2016,31(22):1691-1696..核心期刊
36. Chen XP, Sun SZ, Guo JY, Li JJ, Xie ZD*..Complete Genome Sequence Analysis of Echovirus 18 Associated with Aseptic Meningitis in Hebei Province, China, in 2015. Genome Announc.. 2016,4(5). :pii:e01165-16..
37. Xiang Z, Xie Z, Liu L, Ren L, Xiao Y, Paranhos-Baccalà G, Wang J*..Genetic divergence of enterovirus D68 in China and the United States. Sci Rep.. 2016,6:27800.SCI
38. Gu H#, Xie Z#, Li T#, Zhang S#, Lai C, Zhu P, Wang K, Han L, Duan Y, Zhao Z, Yang X, Xing L, Zhang P, Wang Z, Li R, Yu JJ, Wang X, Yang P.Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus. Sci Rep.. 2016,6:19840.SCI
39. Wang Y, Ai J, Xie Z*, Qin Q, Wu L, Liu Y, Liu C, Shen K*..IL-10-592 A/C polymorphisms is associated with EBV-HLH in Chinese children. Hematology. 2016,21(2):95-98.SCI
40. 谢正德，申昆玲.重视儿童EB病毒感染及其相关疾病的诊治. 中华实用儿科临床杂志. 2016,31(22):1681-1682..核心期刊
41. 周晨, 谢正德*,申昆玲*.EBV编码miRNA的研究进展. 中华实验和临床病毒学杂志. 2015,29(3):287-289.核心期刊
42. 钱艺，谢正德*， 任丽丽， 刘春艳，肖艳， 徐保平， 杨燕， 钱素云， 耿荣，申昆玲..2007-2015年北京地区儿童急性下呼吸道感染人冠状病毒检测及临床分析. 中华儿科杂志. 2015,53（9）:707-711.核心期刊
43. 朱云，郭佳运，谢正德*，刘春艳，任丽丽，肖艳，徐保平，杨燕，钱素云，耿荣，申昆玲..2007年至2014年北京地区儿童急性下呼吸道流感病毒感染临床分析. 中华实用儿科临床杂志. 2015,30(24):1883-1887.核心期刊
44. Gao L, Ai J, Xie Z*, Zhou C, Liu C, Zhang H, Shen K*..Dynamic expression of viral and cellular microRNAs in infectious mononucleosis caused by primary Epstein-Barr virus infection in children. Virol J. 2015,12(1):208.SCI
45. 鲁伟峰,艾军红,刘亚丽,刘春艳,谢正德*.北京地区儿童EBV感染疾病中EBER基因变异特征分析. 中华实验和临床病毒学杂志. 2015,29(2):124-126.核心期刊
46. 张枫, 谢正德*.呼吸道合胞病毒F基因及蛋白的相关研究进展. 病毒学报. 2015,31(2):201-206..核心期刊
47. 陈祥鹏, 张枫, 郭佳运, 朱云, 刘春艳, 谢正德*.北京地区急性呼吸道感染儿童RSV F蛋白抗原位点变异分析. 中华实验和临床病毒学杂志. 2015,29(5):409-412.核心期刊
48. 鲁伟峰, 谢正德*.Epstein-Barr 病毒EBER基因及其生物学特性研究进展. 国际流行病学传染病学杂志. 2014,41(1)::47-50.核心期刊
49. Weifeng Lu, Junhong Ai, Yali Liu, Chunyan Liu, Zhengde Xie*.Characteristics of viral IL-10 gene in Epstein–Barr virus infection in children in China. Future Virol. 2014,9(10):891-897.SCI
50. Xiang Z, Tsatsral S, Liu C, Li L, Ren L, Xiao Y, Xie Z, Zhou H, Vernet G, Nymadawa P, Shen K, Wang J. .Respiratory infection with enterovirus genotype C117, China and Mongolia. Emerg Infect Dis. 2014,20(6):1075-7.SCI
51. Liwei Gao, Zhengde Xie*, Kunling Shen*.Epstein-Barr Virus Associated Infectious Diseases in Children. Am. J. Biomed. Sci.. 2014,6(4): 217-228.
52. 刘亚丽，艾军红，闫静，关晓蕾，刘春艳，谢正德*.北京地区近5年来儿童EB病毒感染疾病中BZLF1及其启动区Zp基因特征分析. 病毒学报. 2014,30（1）:9-15.核心期刊
53. 钱艺,谢正德*.四种人新型冠状病毒的研究进展. 中华传染病杂志. 2014,32(9):573-576.核心期刊
54. 刘春艳, 肖艳, 谢正德, 任丽丽, 胡英惠, 幺远, 杨燕, 钱素云, 赵成松, 申昆玲.2010至2012年门诊和住院儿童急性呼吸道感染病毒病原比较分析. 中华儿科杂志. 2013,51(4):255-259.核心期刊
55. 艾军红, 谢正德*, 刘春艳, 徐保平, 胡英惠, 申昆玲.婴幼儿呼吸道和胞病毒和人鼻病毒急性下呼吸道感染临床特征及随访研究. 中华临床医师杂志. 2013,7(21):20-22.核心期刊
56. 王亚丽,吴凌燕,秦强,谢正德,申昆玲.北京地区汉族儿童细胞因子基因多态性特征. 中华实用儿科临床杂志. 2013,28(15):1162-1165.核心期刊
57. Chen Zhang, Na Zhu, Zhengde Xie﹟, Roujian Lu, Bin He, Chunyan Liu, Xuejun Ma, Wenjie Tan.Viral Etiology and Clinical Profiles of Children with Severe Acute Respiratory Infections in China.. PLoS ONE. 2013,8(8):e72606.SCI
58. Lu G, Li J, Xie Z﹟, Liu C, Guo L, Vernet G, Shen K, Wang J..Human metapneumovirus associated with community-acquired pneumonia in children in Beijing, China.. J Med Virol. 2013,85(1):138-43.SCI
59. Xiang Z, Xie Z, Wang Z, Ren L, Xiao Y, Li L, Vernet G, Paranhos-Baccalà G, Shen K, Wang J..Human enterovirus genotype C104, China [letter]. Emerg Infect Dis. 2013,19(4):689–691.SCI
60. 谢正德.临床医学专业学位研究生培养中存在的问题及对策. 西北医学教育. 2013,21(S):44-46.
61. Ai J, Xie Z, Liu C, Huang Z, Xu J..Analysis of EBNA-1 and LMP-1 variants in diseases associated with EBV infection in Chinese children.. Virol J. 2012,11;9:13.SCI
62. Zhizhuo H, Junmei X, Yuelin S, Qiang Q, Chunyan L, Zhengde X, Kunling S..Screening the PRF1, UNC13D, STX11, SH2D1A, XIAP, and ITK gene mutations in Chinese children with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.. Pediatr Blood Cancer. 2012,58(3):410-414.SCI
63. 秦强,　谢正德,　刘春艳,　黄志卓,　王亚丽,　张寒,　赵晓曦, 申昆玲..儿童ＥＢ病毒相关噬血细胞淋巴组织细胞增生症ＮＫ细胞表面受体和ＣＤ１０７ａ表达. 中国循证儿科杂志. 2012,7(2):136-140.核心期刊
64. 艾军红,谢正德*,刘春艳,高立伟,闫静.2005--2010年北京地区儿童原发性EBV感染流行株EBNAl与LMPl基因特征分析. 中华实验和临床病毒学杂志. 2012,26（5）:352-355.核心期刊
65. Naiying Mao, Yixin Ji, Zhengde Xie#, Huanhuan Wang, Huiling Wang, Junjing An,Xinxin Zhang, Yan Zhang, Zhen Zhu, Aili Cui, Songtao Xu, Kunling Shen, Chunyan Liu,Weizhong Yang, Wenbo Xu.Human Parainfluenza Virus-Associated Respiratory Tract Infection among Children and Genetic Analysis of HPIV-3 Strains in Beijing, China. PLoS ONE. 2012,7（8）: e43893.SCI
66. Qiang Q, Zhengde X, Chunyan L, Zhizhuo H, Junmei X, Junhong A, Zheng C, Henter JI, Kunling S.Killer cell immunoglobulin-like receptor gene polymorphisms predispose susceptibility to EBV associated hemophagocytic lymphohistiocytosis in Chinese children.. Microbiol Immunol. 2012,56:378-384.SCI
67. Lili Ren, Richard Gonzalez, Zhengde Xie, Zhaohui Xiong, Chunyan Liu, Zichun Xiang, Yan Xiao, Yongjun Li, Hongli Zhou, Jianguo Li, Qingqing Yang, Jing Zhang, Lan Chen, Wei Wang, Guy Vernet, Gláucia Paranhos-Baccalà, Kunling Shena, Jianwei Wang..Human parainfluenza virus type 4 infection in Chinese children with lower respiratory tract infections: A comparison study.. J Clin Virol. 2011,51(3):209-212.SCI
68. 谢正德,肖艳, 刘春艳, 胡英惠, 幺远, 杨燕, 钱素云, 耿荣,王健伟, 申昆玲..儿童急性下呼吸道感染病毒病原学2007-2010年监测.. 中华儿科杂志. 2011,49(10):745-749.核心期刊
69. 刘春艳, 肖艳, 张辉, 赵成松, 谢正德*,申昆玲.儿童急性呼吸道感染病毒感染特点分析. 中国实用儿科杂志. 2010,25(8):631-633.核心期刊
70. 王群，谢正德.儿童EB病毒相关疾病的诊断标准和治疗原则. 实用儿科临床杂志. 2010,25(10):706-708.核心期刊
71. 高立伟, 谢正德, 幺远, 杨双, 刘亚谊, 王燕, 姚瑶, 申昆玲..儿童EB病毒感染传染性单核细胞增多症的临床特征. 实用儿科临床杂. 2010, 25(10):725-727.核心期刊
72. 吕典一, 秦茂权, 王燕, 高立伟, 谢正德*.儿童造血干细胞移植患者人巨细胞病毒与疱疹病毒6型感染及相互关系. 中华实验和临床病毒学杂志. 2010,24(6):455-457.核心期刊
73. 谢正德.EB病毒相关噬血淋巴组织细胞增生症. 中国实用儿科杂志. 2010,25（8）:580-582.核心期刊
74. 金颖康, 谢正德, 杜忠东, 杨双, 申昆玲.儿童Epstein-Barr病毒相关性噬血细胞性淋巴组织细胞增生症的回顾性分析. 首都医科大学学报. 2010,31(2):192-196.核心期刊
75. lili Ren, Richard Gonzalez, Zhengde Xie, Yan Xiao, Yongjun Li, Chunyan Liu, Lan Chen, Qingqing Yang, Guy Vernet, Gláucia Paranhos-Baccalà, Qi Jin, Kunling Shen,and Jianwei Wang.Saffold Cardioviruses of 3 Lineages in Children with Respiratory Tract Infections, Beijing, China. Emerg Infect Dis. 2010,16(7):1158-1161.SCI
76. Zichun Xiang, Richard Gonzalez, Zhengde Xie, Yan Xiao, Jun Liu, Lan Chen, Chunyan Liu, Jing Zhang, Lili Ren, Guy Vernet, Gláucia Paranhos-Baccalà, Kunling Shen,, Qi Jin, Jianwei Wang.Human rhinovirus C infections mirror those of human rhinovirus A in children with community-acquired pneumonia. J Clin Virol. 2010,49(1) :94–99.SCI
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1. 重要和新发现呼吸道及肠道病毒的病原学研究及其应用 教育部高等学校科学研究优秀成果奖（科学技术） 科学技术进步二等奖 201603
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