姓名：段军超 性别：女 职称：教授 招生院所：公共卫生学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：卫生毒理学(博) 卫生毒理学(硕) 研究方向名称：心血管毒理学，环境毒理学 电子信箱：jcduan@ccmu.edu.cn


社会任职
1. 中华预防医学会卫生毒理分会青年委员会，副主任委员
2. 中国环境诱变剂学会致突变专委会青年委员会，副主任委员
3. 中国毒理学会遗传毒理学专业委员会，委员
4. 中国环境诱变剂学会青年委员会，委员
5. 北京预防医学会第七届卫生毒理专业委员会，委员
个人简历
1. 200409-200907:首都医科大学 学士
2. 200909-201407:首都医科大学 博士
3. 201408-201612:首都医科大学 讲师
4. 201701-201912:首都医科大学 副教授
5. 202001-:首都医科大学 教授
重要学术论文
1. Baiyang Sun#, Yanfeng Shi#, Yang Li, Jinjin Jiang, Shuang Liang, Junchao Duan*, Zhiwei Sun*.Short-term PM2.5 exposure induces sustained pulmonary fibrosis development during post-exposure period in rats. Journal of Hazardous Materials. 2020,385:121566.SCI
2. Shuang Liang#, Yueyue Chen#, Shiming Zhang, Yuanyuan Cao, Yapei Wang*, Junchao Duan*, Zhiwei Sun*.RhB-encapsulating Silica Nanoparticles Modified with PEG impact the Vascular Endothelial Function in Endothelial Cells and Zebrafish Model. Science of the total environment. 2020,711:134493.SCI
3. Lin Feng#, Ruihong Ning#, Jiangyan Liu, Shuang Liang, Qing Xu, Ying Liu, Wei Liu*, Junchao Duan*, Zhiwei Sun.Silica nanoparticles induce JNK-mediated inflammation and myocardial contractile dysfunction. Journal of Hazardous Materials. 2020,391:122206.SCI
4. Liangshuang Zhang#, Jialiu Wei#, Junchao Duan#, Caixia Guo, Jin Zhang, Lihua Ren, Jianhui Liu, Yanbo Li*, Zhiwei Sun, Xianqing Zhou*.Silica Nanoparticles exacerbates reproductive toxicity development in high-fat diet-treated Wistar rats. Journal of Hazardous Materials. 2020,384:121361.SCI
5. Jinjin Jiang, Yang Li, Shuang Liang, Baiyang Sun, Yanfeng Shi, Qing Xu, Jie Zhang, Heqing Shen, Junchao Duan*, Zhiwei Sun*.Combined exposure of fine particulate matter and high-fat diet aggravate the cardiac fibrosis in C57BL/6J mice. Journal of Hazardous Materials. 2020,391:122203.SCI
6. Jingyi Zhang#, Shuang Liang#, Ruihong Ning, Jinjin Jiang, Jie Zhang, Heqing Shen, Rui Chen, Junchao Duan*, Zhiwei Sun*.PM2.5-induced inflammation and lipidome alteration associated with the development of atherosclerosis based on a targeted lipidomic analysis. Environment International. 2020,136:105444.SCI
7. Yanfeng Shi, Tong Zhao, Xiaozhe Yang, Baiyang Sun, Yang Li, Junchao Duan*, Zhiwei Sun*.PM2.5-induced the alteration of DNA methylation and RNA-transcription are associated with inflammatory response and lung injury. Science of the Total Environment. 2019,650:908-921.SCI
8. Shuang Liang#, Tong Zhao#, Hejing Hu, Yanfeng Shi, Qing Xu, Mark R. Miller, Junchao Duan*, Zhiwei Sun*.Repeat dose exposure of PM2.5 triggers the Disseminated Intravascular Coagulation (DIC) in SD Rats. Science of the Total Environment. 2019,663:245-253.SCI
9. Jiangyan Liu#, Shuang Liang#, Zhou Du, Jingyi Zhang, Baiyang Sun, Tong Zhao, Xiaozhe Yang, Yanfeng Shi, Junchao Duan*, Zhiwei Sun.PM2.5 aggravates the lipid accumulation, mitochondrial damage and apoptosis in macrophage foam cells. Environmental Pollution. 2019,249:482-490.SCI
10. Lin Feng, Xiaozhe Yang, Shuang Liang, Qing Xu, Mark R. Miller, Junchao Duan*, Zhiwei Sun*.Silica nanoparticles trigger the vascular endothelial dysfunction and prethrombotic state via miR-451 directly regulating the IL6R signaling pathway. Particle and Fibre Toxicology. 2019,16:16.SCI
11. Yannan Zhang#, Mengtian Chu#, Jingyi Zhang, Junchao Duan*, Dayu Hu, Wenlou Zhang, Xuan Yang, Xu Jia, Furong Deng*, Zhiwei Sun*.Urine metabolites associated with cardiovascular effects from exposure of size-fractioned particulate matter in a subway environment: a randomized crossover study. Environment International. 2019,130:104920.SCI
12. Yang Yu, Tingting Zhu, Yang Li, Li Jing, Man Yang, Yanbo Li, Junchao Duan*, Zhiwei Sun*.Repeated intravenous administration of silica nanoparticles induces pulmonary inflammation and collagen accumulation via JAK2/STAT3 and TGF-β/Smad3 pathways in vivo. International Journal of Nanomedicine. 2019,14:7237-7247.SCI
13. Yang Li#, Junchao Duan#, Xiangyuan Chai, Man Yang, Ji Wang, Rui Chen*, Zhiwei Sun*.Microarray assisted size effect study of amorphous silica nanoparticles on human bronchial epithelial cells. Nanoscale. 2019,11(47):22907-22923.SCI
14. Xiaozhe Yang, Tong Zhao, Lin Feng, Yanfeng Shi, Jinjin Jiang, Shuang Liang, Baiyang Sun, Qing Xu, Junchao Duan*, Zhiwei Sun*.PM2.5-induced ADRB2 hypermethylation contributed to cardiac dysfunction through cardiomyocytes apoptosis via PI3K/Akt pathway. Environment International. 2019,127:601-614.SCI
15. Baiyang Sun, Yanfeng Shi, Xiaozhe Yang, Tong Zhao, Junchao Duan*, Zhiwei Sun*.DNA methylation: A critical epigenetic mechanism underlying the detrimental effects of airborne particulate matter. Ecotoxicology and Environmental Safety. 2018,161:173-183.SCI
16. Yannan Zhang, Yanbo Li, Zhixiong Shi, Jing Wu, Xiaozhe Yang, Lin Feng, Lihua Ren, Junchao Duan*, Zhiwei Sun*.Metabolic impact induced by total, water soluble and insoluble components of PM2.5 acute exposure in mice. Chemosphere. 2018,207:337-346.SCI
17. Xiaozhe Yang, Lin Feng, Yannan Zhang, Hejing Hu, Yanfeng Shi, Shuang Liang, Tong Zhao, Yang Fu, Junchao Duan*, Zhiwei Sun*.Cytotoxicity induced by fine particulate matter (PM2.5) via mitochondria-mediated apoptosis pathway in human cardiomyocytes. Ecotoxicology and Environmental Safety. 2018,161:198-207.SCI
18. Collins Otieno Asweto#, Hejing Hu#, Shuang Liang#, Lijing Wang, Mengdi Liu, Han Yang, Junchao Duan*, Zhiwei Sun.Gene profiles to characterize the combined toxicity induced by low level co-exposure of silica nanoparticles and benzo[a]pyrene using whole genome microarrays in zebrafish embryos. Ecotoxicology and Environmental Safety. 2018,163:47-55.SCI
19. Xiaozhe Yang, Lin Feng, Yannan Zhang, Yanfeng Shi, Shuang Liang, Tong Zhao, Baiyang Sun, Junchao Duan*, Zhiwei Sun*.Integrative analysis of methylome and transcriptome variation of identified cardiac disease-specific genes in human cardiomyocytes after PM2.5 exposure. Chemosphere. 2018,212:915-926.SCI
20. Junchao Duan, Shuang Liang, Lin Feng, Yang Yu*, Zhiwei Sun*.Silica nanoparticles trigger the hepatic lipid metabolism disorder in vivo and in vitro. International Journal of Nanomedicine. 2018,13:7303-7318.SCI
21. Lin Feng, Xiaozhe Yang, Yanfeng Shi, Shuang Liang, Tong Zhao, Junchao Duan*, Zhiwei Sun*.Co-exposure subacute toxicity of silica nanoparticles and lead acetate on cardiovascular system. International Journal of Nanomedicine. 2018,13:7819-7834.SCI
22. Junchao Duan, Shuang Liang, Yang Yu, Yang Li, Lijing Wang, Zehao Wu, Yueyue Chen*, Mark R. Miller, Zhiwei Sun*.Inflammation-coagulation Response and Thrombotic Effects Induced by Silica Nanoparticles in Zebrafish Embryos. Nanotoxicology. 2018,12(5):470-484.SCI
23. Xiaozhe Yang, Lin Feng, Yannan Zhang, Hejing Hu, Yanfeng Shi, Shuang Liang, Tong Zhao, Lige Cao, Junchao Duan*, Zhiwei Sun*.Co-exposure of silica nanoparticles and methylmercury induced cardiac toxicity in vitro and in vivo. Science of the Total Environment. 2018,631-632:811-821.SCI
24. Hejing Hu#, Collins Otieno Asweto#, Jing Wu, Yanfeng Shi, Lin Feng, Xiaozhe Yang, Shuang Liang, Lige Cao, Junchao Duan*, Zhiwei Sun*.Gene expression profiles and bioinformatics analysis of human umbilical vein endothelial cells exposed to PM2.5. Chemosphere. 2017,183:589-598.SCI
25. Collins Otieno Asweto, Jing Wu, Mohamed Ali Alzain, Hejing Hu, Sebastian Andrea, Lin Feng , Xiaozhe Yang, Junchao Duan*, Zhiwei Sun*.Cellular pathways involved in silica nanoparticles induced apoptosis: A systematic review of in vitro studies. Environmental Toxicology and Pharmacology. 2017,56:191-197.SCI
26. Hejing Hu, Yanfeng Shi, Yannan Zhang, Jing Wu, Collins Otieno Asweto, Lin Feng, Xiaozhe Yang, Junchao Duan*, Zhiwei Sun*.Comprehensive gene and microRNA expression profiling on cardiovascular system in zebrafish co-exposured of SiNPs and MeHg. Science of the Total Environment. 2017,608:795-805.SCI
27. Lin Feng, Xiaozhe Yang, Collins Otieno Asweto, Jing Wu, Yannan Zhang, Hejing Hu, Yanfeng Shi, Junchao Duan*, Zhiwei Sun.Low-dose combined exposure of nanoparticles and heavy metal compared with PM2.5 in human myocardial AC16 cells. Environmental science and pollution research. 2017,24(36):27767-27777.SCI
28. Junchao Duan*, Hejing Hu, Lin Feng, Xiaozhe Yang, Zhiwei Sun.Silica nanoparticles inhibit macrophage activity and angiogenesis via VEGFR2-mediated MAPK signaling pathway in zebrafish embryos. Chemosphere. 2017,183:483-490.SCI
29. Hejing Hu, Yannan Zhang, Yanfeng Shi, Lin Feng, Junchao Duan*, Zhiwei Sun.Zhiwei Sun. Microarray-based bioinformatics analysis of the combined effects of SiNPs and PbAc on cardiovascular system in zebrafish. Chemosphere. 2017,184:1298-1309.SCI
30. Jing Wu#, Yanfeng Shi#, Collins OtienoAsweto, Lin Feng, Xiaozhe Yang,Yannan Zhang, Hejing Hu, Junchao Duan*, Zhiwei Sun*.Fine particle matters induce DNA damage and G2/M cell cycle arrest in human bronchial epithelial BEAS-2B cells. Environmental science and pollution research. 2017,24(32):25071-25081.SCI
31. Lin Feng, Xiaozhe Yang, Collins Otieno Asweto, Jing Wu, Yannan Zhang, Hejing Hu, Yanfeng Shi, Junchao Duan*, Zhiwei Sun*.Genome-wide transcriptional analysis of cardiovascular-related genes and pathways induced by PM2.5 in human myocardial cells. Environmental science and pollution research. 2017,24(12):11683-11693.SCI
32. Collins Otieno Asweto, Jing Wu, Hejing Hu, Lin Feng, Xiaozhe Yang, Junchao Duan*, Zhiwei Sun*.Combined Effect of Silica Nanoparticles and Benzo[a]pyrene on Cell Cycle Arrest Induction and Apoptosis in Human Umbilical Vein Endothelial Cells. Int. J. Environ. Res. Public Health. 2017,14(3):289.SCI
33. Junchao Duan, Yang Yu, Yang Li, Li Jing, Man Yang, Ji Wang, Yanbo Li, Xianqing Zhou, Mark R. Miller, Zhiwei Sun*.Comprehensive understanding of PM2.5 on gene and microRNA expression patterns in zebrafish (Danio rerio) model. Science of the Total Environment. 2017,586:666-674.SCI
34. Junchao Duan, Hejing Hu, Yannan Zhang, Lin Feng, Yanfeng Shi, Mark R. Miller*, Zhiwei Sun*.Multi-organ toxicity induced by fine particulate matter PM2.5 in zebrafish (Danio rerio) model. Chemosphere. 2017,180:24-32.SCI
35. Yannan Zhang, Hejing Hu, Yanfeng Shi, Xiaozhe Yang, Lige Cao, Jing Wu, Collins Otieno Asweto, Lin Feng, Junchao Duan*, Zhiwei Sun*.1H NMR-Based Metabolomics Study on Repeat Dose Toxicity of Fine Particulate Matter in Rats after Intratracheal Instillation. Science of the Total Environment. 2017,589:212-221.SCI
36. Jing Wu, Yanfeng Shi, Collins Asweto, Lin Feng, Xiaozhe Yang, Yannan Zhang, Hejing Hu, Junchao Duan*, Zhiwei Sun*.Co-exposure to amorphous silica nanoparticles and benzo[a]pyrene at low level in human bronchial epithelial BEAS-2B cells. Environmental science and pollution research. 2016,23(22):23134-23144.SCI
37. Junchao Duan*, Yang Yu, Yang Li, Yapei Wang, Zhiwei Sun*.Inflammatory response and blood hypercoagulable state induced by low level co-exposure with silica nanoparticles and benzo[a]pyrene in zebrafish (Danio rerio) embryos. Chemosphere. 2016,151:152-162.SCI
38. Junchao Duan, Yang Yu, Yang Li, Yanbo Li, Hongcui Liu, Li Jing, Man Yang, Ji Wang, Chunqi Li, Zhiwei Sun*.Low-dose exposure of silica nanoparticles induces cardiac dysfunction via neutrophil-mediated inflammation and cardiac contraction in zebrafish embryos. Nanotoxicology. 2016,10(5):575-585.SCI
39. Junchao Duan*, Hejing Hu, Qiuling Li, Lizhen Jiang, Yang Zou, Yapei Wang*, Zhiwei Sun*.Combined toxicity of silica nanoparticles and methylmercury on cardiovascular system in zebrafish (Danio rerio) embryos. Environmental Toxicology and Pharmacology. 2016,44:120-127.SCI
40. Junchao Duan, Yongbo Yu, Yang Yu, Yang Li, Ji Wang, Weijia Geng, Lizhen Jiang, Qiuling Li, Xianqing Zhou*, Zhiwei Sun*.Silica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathway. International Journal of Nanomedicine. 2014,9:5131-5141.SCI
41. Junchao Duan, Yongbo Yu, Yang Yu, Yang Li, Peili Huang, Xianqing Zhou, Shuangqing Peng, Zhiwei Sun*.Silica nanoparticles induce autophagic activity, disturb endothelial cell homeostasis and impair angiogenesis. Particle and Fibre Toxicology. 2014,11:50.SCI
42. Yongbo Yu#, Junchao Duan#, Yang Yu, Yang Li, Xiaomei Liu, Xianqing Zhou, Kin-fai Ho, Linwei Tian*, Zhiwei Sun*.Silica nanoparticles induce autophagy and autophagic cell death in HepG2 cells triggered by reactive oxygen species. Journal of Hazardous Materials. 2014,270:176-86.SCI
43. Junchao Duan, Yongbo Yu, Yang Li, Yang Yu, Zhiwei Sun*.Cardiovascular toxicity evaluation of silica nanoparticles in endothelial cells and zebrafish model. Biomaterials. 2013,34(23):5853-62.SCI
主编或副主编的著作/译著
重要奖项
1. 中国毒理学会优秀青年科技奖 2018
2. 北京市青年拔尖人才 2018
3. 北京市科技新星 2017
4. 英国皇家化学会优秀论文奖 2017
5. 中国科协青年人才托举工程 2017
6. 中国毒理学-联合利华毒理学替代法创新奖 2016