姓名：罗玉敏 性别：女 职称：主任医师、教授 招生院所：附属宣武医院 招生类型：科学学位(博) 科学学位(硕) 招生专业：神经病学(博) 神经病学(硕) 研究方向名称：脑卒中临床基础研究 电子信箱：yumin_l@hotmail.com


社会任职
1. 北京药理学会心脑血管药理学专业委员会 常委
2. 北京市中西医结合学会神经科专业委员会 主任委员
3. 北京市神经科学学会 理事
4. 北京市中西医结合学会 理事
5. 中国民族医药学会脑病分会 常务理事
6. 北京神经内科学会中西医结合专业委员会 副主任委员
7. 中国微循环学会痰瘀专业委员会 副主任委员
个人简历
1. 198409-198907:中国医科大学 学生
2. 198909-199208:中国医科大学第二临床学院神经科 89级硕士研究生
3. 199209-199308:中国医科大学第二临床学院神经科 住院医师
4. 199309-199408:中国医科大学第二临床学院神经科 总住院医师
5. 199409-199608:中国医科大学第二临床学院神经科 主治医师，讲师
6. 199609-199804:复旦大学华山医院神经科（原上海医科大学） 九六级博士生
7. 199805-199904:美国匹兹堡大学神经科 联合培养博士研究生
8. 199905-199907:复旦大学华山医院神经科（原上海医科大学） 九六级博士生
9. 199908-199910:中国医科大学第二临床学院神经科 主治医师，讲师
10. 199911-200108:复旦大学华山医院神经科（原上海医科大学） 主治医师，讲师
11. 200109-200203:美国匹兹堡大学神经科 进修学习
12. 200204-200412:复旦大学华山医院神经科 副主任医师，副教授，硕士生导师
13. 200501-200609:美国匹兹堡大学神经科 高级访问
14. 200610-:首都医科大学宣武医院 研究员，脑血管病研究室主任，首都医科大学脑血管病研究所副所长
15. 201611-:首都医科大学宣武医院 主任医师，宣武医院神经内科中西医结合专业组副组长
重要学术论文
1. Haiping Zhao#, Guangwen Li#, Rongliang Wang, Zhen Tao, Qingfeng Ma, Sijia Zhang, Ziping Han, Feng Yan, Fangfang Li, Ping Liu, Shubei Ma, Xunming Ji, Yumin Luo*.HDAC2 impairs Th1 skewed neurotoxicity in acuteischemic stroke：a novel miR-494-based therapeutic pathway. Br J Pharmacol. 2020,177 (1):128-144.SCI
2. Haiping Zhao#, Guangwen Li#, Sijia Zhang, Zhen Tao, Rongliang Wang, Qingfeng Ma, Ziping Han, Fangfang Li, Lingzhi Li, Xunming Ji, Yumin Luo*..HDAC3 Inhibition by MicroRNA-494 Alleviates Neuronal Loss and Enhances Functional Recovery in Mouse Models of Ischemic Stroke.. JCBFM. 2019,39(12):2392-2405.SCI
3. Ping Liu, Ziping Han, Qingfeng Ma, Tao Liu, Rongliang Wang, Zhen Tao, Guangwen Li, Fangfang Li, Sijia Zhang, Xuming Ji, Haiping Zhao*, Yumin Luo*..Upregulation of MicroRNA-128 in the Peripheral Blood of Acute Ischemic Stroke Patients is Correlated with Stroke Severity Partially through Inhibition of Neuronal Cell Cycle Reentry and Apoptosis. Cell Transplant. 2019,28(7):839-850.SCI
4. Haiping Zhao, Guangwen Li, Rongliang Wang, Zhen Tao, Sijia Zhang, Fangfang Li, Ziping Han, Lingzhi Li, Ping Liu, Yumin Luo*.MiR-424 prevents astrogliosis after cerebral ischemia in middle-aged mice by enhancing repressive H3K27me3 via targeting the NFIA/DNMT1 pathway. FEBS J. 2019,286(24):4926-4936.SCI
5. Wei Zhuang, Wei Gong, Xiaofang Dang, Fei Chen, Ziping Han, Xiaolan Lin*, Yumin Luo*..Rosenroot (Rhodiola rosea): potiential effects for anti-aging and aging-related diseases. Aging and diseases. 2019,10（1）:134-136.SCI
6. Shubei Ma, Jianyi Wang, Yanling Wang, Xuejiao Dai, Fei Xu, Xuguang Gao, Joycelyne Johnson, Na Xu, Rehana K. Leak, Xiaoming Hu, Yumin Luo*, and Jun Chen*..Diabetes Mellitus Impairs White Matter Repair and Long-Term Functional Deficits After Cerebral Ischemia. Stroke. 2018,49(10):2453–2463 .SCI
7. Guangwen Li, Morris-Blanco KC, Mary S. Lopez, Haiping Zhao, Raghu Vemuganti*, Yumin Luo*. .Impact of microRNAs on ischemic stroke: From pre- to post-disease. Progress in Neurobiolgy. 2018,164:59-78.SCI
8. Guangwen Li, Qingfeng Ma, Rongliang Wang, Zhibin Fan, Zhen Tao, Ping Liu, Haiping Zhao*, Yumin Luo* .Diagnostic and Immunosuppressive Potential of Elevated Mir-424 Levels in Circulating Immune Cells of Ischemic Stroke Patients. Aging and diseases. 2018,9（2）:172-181.SCI
9. Haiping Zhao, Ziping Han, Sijia Zhang, Guangwen Li, Yumin Luo*.Therapeutic potential and cellular mechanisms of Panax notoginseng on prevention of aging and cell senescence-associated diseases. Aging and diseases. 2017,8（6）:721-739.SCI
10. Haiping Zhao, Yumin Luo*.Traditional Chinese Medicine and Aging Intervention. Editorial. Aging and Disease. 2017,8（6）:688-690.SCI
11. Rongliang Wang, Jincheng Li, Yunxia Duan, Zhen Tao, Ping Liu, Haiping Zhao, Yumin Luo*.Effects of erythropoietin on gliogenesis during cerebral ischemic/reperfusion recovery in mice. Aging and Disease. 2017,8 (4):410-419.SCI
12. Zhifeng Qi, Jia Liang, Rong Pan, Wen Dong, Yongmei Zhao, Wenjuan Shi, Yumin Luo, Xunming Ji, Ke Jian Liu*.Zinc contributes to cerebral ischemia-induced increase in BBB permeability in vitro and in vivo. Neurobiology of Disease. 2016,95:12-21.SCI
13. Qingfeng Ma, Haiping Zhao, Zhen Tao, Rongliang Wang, Ping Liu, Ziping Han, Shubei Ma, Yumin Luo*.MicroRNA-181c exacerbates brain injury in acute ischemic stroke. Aging and Diseases. 2016,7 (6):705-714.SCI
14. Xiangrong Liu,Jun Kang, Fang Liu, Shaohong Wen, Xianwei Zeng, Kuan Liu, Yumin Luo, Xunming Ji, Shangfeng Zhao.Overexpression of iASPP-SV in glioma is associated with poor prognosis by promoting cell viability and antagonizing apoptosis. Tumour Biol. 2016,37(5):6323-50.SCI
15. HaipingZhao, Ziping Han, Xunming Ji*, Yumin Luo*.Epigenetic regulation of oxidativestress in ischemic stroke. Aging and Diseases. Aging and Diseases. 2016,7(3):295-306.SCI
16. Ping Liu#, Haiping Zhao#, Rongliang Wang, Wang P, Zhen Tao, Li Gao, Feng Yan, Xiangrong Liu, Shun Yu, Xunming Ji, Yumin Luo*.MicroRNA-424 protects against focal cerebral ischemia and reperfusion injury in mice by suppressing oxidative stress.. Stroke. 2015,46(2):513-519.SCI
17. Ziping Han, Xiangrong Liu, Yumin Luo, Xunming Ji*.Hypothermia for stroke: where to go?. Exeperimental Neurology. 2015,272:67-77.SCI
18. Shubei Ma, Haiping Zhao, Xunming Ji*, Yumin Luo*.Peripheral to Central: Organ Interactions in Stroke Pathophysiology. Exeperimental Neurology. 2015,272:41-49.SCI
19. Haiping Zhao, Rongliang Wang, Xiaoning Wu, Jia Liang, Zhifeng Qi, Xiangrong Liu, Lianqiu Min, Xunming Ji, Yumin Luo*.Intra-artery infusion of low-dose erythropoietin reduced blood-brain barrier disruption in rats following cerebral ischemia and reperfusion. J Neuroimmune Pharmacol. 2015,10(1):153-161.SCI
20. Jia Liang, Zhifeng Qi, Wenlan Liu, Peng Wang, Wenjuan Shi, Wen Dong, Xunming Ji, Yumin Luo*, Ke Jian Liu*.Normobaric hyperoxia slows BBB damage and expands the therapeutic time window for tPA treatment in cerebral ischemia. Stroke. 2015,46(5):1344-13451.SCI
21. Haiping Zhao, Rongliang Wang, Zhen Tao, Li Gao, Feng Yan, Zhi Gao, Xiangrong Liu, Xunming Ji, Yumin Luo*. .Ischemic Postconditioning Relieves Cerebral Ischemia and Reperfusion Injury through Activating TOPK/Akt Pathway in Rats.. Stroke. 2014,45:2417-2424.SCI
22. Haiping Zhao, Zhen Tao, Rongliang Wang, Ping Liu, Feng Yan, Jincheng Li, Chencheng Zhang, Xunming Ji, Yumin Luo*. .MicroRNA-23a-3p attenuates oxidative stress injury in a mouse model of focal cerebral ischemia-reperfusion.. Brain Research. 2014,1592:65-72.SCI
23. Haiping Zhao#, Yumin Luo#, Xiangrong Liu, Rongliang Wang, Feng Yan, Sijie Li, Leak RK, Xunming Ji..Ischemic post-conditioning partially reverses cell cycle reactivityfollowing ischemia/reperfusion injury: a genome-wide survey.. CNS & Neurological Disorders-Drug Targets.. 2013,12（3）:350-359.SCI
24. Zhi-feng Qi#, Yu-min Luo#, Xiang-rong Liu, Rong-liang Wang, Hai-ping Zhao, Feng Yan, Zhao-jing Song, Mei Luo, Xun-ming Ji..AKT/GSK3β-dependent autophagy contributes to neuroprotection of limb remote ischemic post-conditioning in transient cerebral ischemic rat model.. CNS Neurosci Ther. . 2012,28:965-973.SCI
25. Gao L, Liu P, Song JX, Liu Q, Xu CM, Huang LY, Wang PP, Zhao HP, Luo YM*. .Study on the Relationship between Tongue Manifestation and Fibrinogen, Neutrophil in Acute Cerebral Infarction Patients.. Chin J Integr Med. 2012,18(12):942-945.SCI
26. Li Gao, Haiping Zhao, Qian Liu, Juexian Song, Changmin Xu, Ping Liu, Wei Gong, Rongliang Wang, Ke Jian Liu, Yumin Luo*. .Improvement of hematoma absorption and neurological function in patients with acute intracerebral hemorrhage treated with Xueshuantong. . J Neurol Sci.. 2012,323 (1-2):236-240.SCI
27. Xiang-Rong Liu, Mei Luo, Feng Yan, Chen-Cheng Zhang, Si-Jie Li, Hai-Ping Zhao, Xun-Ming Ji, Yu-Min Luo*. .Ischemic postconditioning diminishes matrix metalloproteinase 9 expression and attenuates loss of the extracellular matrix proteins in rats following middle cerebral artery occlusion and reperfusion.. CNS Neuroscience and Therapeutic.. 2012,18(10):855-863.SCI
28. Hong Zhang, Zhan-Qiang Wang, Dan-Yang Zhao, Dong-Ming Zheng, Juan Feng, Li-Chun Song, Yumin Luo..AIF-mediated Mitochondrial Pathway Is Critical for the Protective Effect of Diazoxide against SH-SY5Y Cell Apoptosis.. Brain Res. 2011,1370:89-98.SCI
29. Ren C, Gao M, Dornbos D 3rd, Ding Y, Zeng X, Luo Y, Ji X..Remote ischemic post-conditioning reduced brain damage in experimental ischemia/reperfusion injury. . Neurol Res. 2011,33(5):514-9.SCI
30. Fujiwara N, Mandeville ET, Geng X, Luo Y, Arai K, Wang X, Ji X, Singhal AB, Lo EH..Effect of normobaric oxygen therapy in a rat model of intracerebral hemorrhage.. Stroke. 2011,42(5):1469-72.SCI
31. Sha Dang，Xiangrong Liu, Fu P, Wei Gong, Feng Yan, Pingxin Han, Xunming Ji* and Yumin Luo*.. Neuroprotection by local intra-arterial infusion of erythropoietin after focal cerebral ischemia in rats. . Neurological Research. . 2011,33(5):520-528.SCI
32. Xiehua Gan, Yumin Luo, Feng Ling, Xunming Ji, Jian Chen, Yuchuan Ding.. Outcome in acute stroke with different intra-arterial infusion rate of urokinase on thrombolysis.. Interv Neuroradiol. . 2010,16(3):290-6..SCI
33. Wang F, Luo Y, Ling F, Wu H, Chen J, Yan F, He Z, Goel G, Ji X, Ding Y. .Comparison of neuroprotective effects in ischemic rats with different ypothermia procedures.. Neurol Res.. 2010,32(4):378-383.SCI
34. Zhang F, Xing J, Liou AK, Wang S, Gan Y, Luo Y, Ji X, Stetler RA, Chen J, Cao G..Enhanced Delivery of Erythropoietin Across the Blood-Brain Barrier for Neuroprotection against Ischemic Neuronal Injury.. Transl Stroke Res. . 2010,1(2):113-121.SCI
35. Jian Chen, Xunming Ji, Yuchuan Ding, Yuming Luo, Huakun Cheng, Feng Ling. .A novel approach to reduce hemorrhagic transformation after interventionalmanagement of acute stroke: Catheter-based selective hypothermia. . Med Hypotheses. 2009,72(1):62-63.SCI
36. Feng Zhang, Shuping Wang, Yumin Luo, Xunming Ji, Edwin M Nemoto, Jun Chen. .When hypothermia meets hypotension and hyperglycemia: the diverse effects of adenosine 5'-monophosphate on cerebral ischemia in rats. . J Cereb Blood Flow Metab. 2009,29(5):1022-1034.SCI
37. Li Gao, Xunming Ji, Juexian Song, Ping Liu, Feng Yan, Wei Gong, Sha Dang, Yumin Luo*..Puerarin Protects against ischemic brain injury in a rat model of transient focal ischemia. Neurol Res. 2009,31 (4):402-406.SCI
38. Li L, Li Y, Ji XM, Pei Z, Zhang B, Luo Y*..The Effects of Retinoic Acid on the Expression of Neurogranin after Experimental Cerebral Ischemia. Brain Research. 2008,1226:234-240.SCI
39. Luo Y, Ji X, Ling F, Li W, Zhang F, Cao G, Chen J.Impaired DNA repair via the base-excision repair pathway after focal ischemic brain injury: a protein phosphorylation-dependent mechanism reversed by hypothermic neuroprotection. Frontier in Bioscience . 2007,12:1852-1862 .SCI
40. Xunming Ji, Yumin Luo, Feng Ling, Anne R Stetler, Jing Lan, Guodong Cao, Jun Chen. .Mild hyppthermia diminished oxidative DNA damage and pro-death signaling events after cerebral ischemia: a mechanism for neuroprotection. . Frontier in Bioscience . 2007,12:1737-1747 .SCI
41. Jianzhen Wang, Xunming Ji, Feng ling, Yumin Luo, Xin He, Yu Xuan. .A new model of reversible superior sagittal sinus thrombosis in rats. . Brain Research. 2007,1181:118-124.SCI
42. Yumin Luo, Wei Yin, Signore AP, Feng Zhang, Zhen Hong, Shuping Wang, Graham SH, and Jun Chen. .Neuroprotection against focal ischemic brain injury by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone. . J Neurochemistry . 2006,97 (2):435-448 .SCI
43. Tianfu Li, Chuanzhen Lu, Zuoli Xia, Baoguo Xiao, Yumin Luo. .Inhibition of caspase-8 attenuates neuronal death induced by limbic seizures in a cytochrome c-dependent and Smac/DIABLO-independent way.. Brain Res. 2006,1098 (1):204-211.SCI
44. Wei Yin, Guodong Cao, Johnnides MJ, Signore AP, Yumin Luo, Hickey RW, Jun Chen. .TAT-mediated delivery of Bcl-xL protein is neuroprotective against neonatal hypoxic-ischemic brain injury via inhibition of caspases and AIF.. Neurobiol Dis.. 2006,21(2):358-371.SCI
45. Tianfu Li, Yongfeng Fan, Yumin Luo, Baoguo Xiao, Chuanzhen Lu..In vivo delivery of a XIAP (BIR3-RING) fusion protein containing the protein transduction domain protects against neuronal death induced by seizure. Exp Neurol . 2006,197 (2):301-308.SCI
46. Wenjin Li, Yumin Luo, Feng Zhang, Gobbel G, Jing Lan, O’Horo C, Simon RP, and Jun Chen. .Ischemic Preconditioning in the Rat Brain Markedly Enhances the Repair of Endogenous Oxidative DNA Damage by Activating the Base-Excision Repair Pathway.. J Cereb Blood Flow Metab. 2006,26 (2):181-198. .SCI
47. Luo Y, Yin W, Signore AP, Zhang F, Hong Z, Wang S, Graham SH, and Chen J.Neuroprotection against focal ischemic brain injury by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone. J Neurochemistry. 2006,97 (2):435-448.SCI
48. Qinhua Zhao, Yumin Luo, Bing Zhou, Zhen Hong. .Insulin aggravates amyloid deposition and cognition impairment in an AD-like rat model. Neuroscience Bulletin. 2005,21(6):408-412.
49. Yanqin Gao, Signore AP, Feng Zhang, Wei Yin, Xiaoming Yin, Fengyan Sun, Yumin Luo, Graham SH, and Jun Chen. .Neuroprotection Against Focal Ischemic Brain Injury by Inhibition of c-Jun N-Terminal Kinase and Attenuation of the Mitochondrial Apoptosis-Signaling Pathway. . J Cereb Blood Flow Metab. 2005,25 (6):694-712.SCI
50. Jianhui Fu, Chuanzhen Lu, Zhen Hong, Qiang Dong, Yumin Luo and Wong KS. .Extent of white matter lesions is related to acute subcortical infarcts and predicts further stroke risk in patients with first ever ischaemic stroke.. J Neuro Neurosurg Psychiatry. 2005,76 (6):793-796.SCI
51. Yumin Luo*, Zhen Hong, Zhen Qin, Xinmin Zhang Jianhui Fu and Weidong Zhang. .Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia. Neuroscience Letters . 2004,363(3):218-223 .SCI
52. Yumin Luo, Guodong Cao, Wei Pei, O’Horo C, Graham SH and Jun Chen. .Induction of Caspase-Activated Deoxyribonuclease Activity After Focal Cerebral Ischemia and Reperfusion.. J Cereb Blood Flow Metab. 2002,22:15-20 .SCI
53. Guodong Cao, Yumin Luo, Nagayama T, Wei Pei, Stetler RA, Graham SH, and Jun Chen.. Cloning and Characterization of Rat Caspase-9: Implications for a Role in Mediating Caspase-3 Activation and Hippocampal Cell Death After Transient Cerebral Ischemia. . J Cereb Blood Flow Metab . 2002,22(5):534-546 .SCI
54. Xiaoming Yin, Yumin Luo, Guodong Cao, Bai L, Wei Pei, Kuharsky DK, Jun Chen. .Bid-mediated mitochondrial pathway is critical to ischemic neuronal apoptosis and focal cerebral ischemia. J Biol Chem. 2002,277(44):42074-42081.SCI
55. Guodong Cao, Wei Pei, Hailiang Ge, Qinghua Liang, Yumin Luo, Sharp FR, Lu A, Ran R, Graham SH, and Jun Chen. .In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects Against Ischemic Brain Injury and Neuronal Apoptosis . J Neurosci. 2002,22(13):5423-5433.SCI
56. Guodong Cao, Wei Pei, Jing Lan, Stetler RA, Yumin Luo, Nagayama T, Graham SH, Xiaoming Yin, Simon RP and Jun Chen..Caspase-activated Dnase/DFF40 Mediates Apoptotic DNA Fragmentation in Transient Cerebral Ischemia and in Neuronal Cultures. Journal of Neuroscience.. Journal of Neuroscience. . 2001,21(13):4687-4690..SCI
主编或副主编的著作/译著
1. 《Traditional Chinese Medicine in Aging and Disease Intervention》,主编,ISOAD,201912
2. 《天然本草养出百岁人生》,主编,中国医药科技出版社,201902
3. 《中西医结合望诊启迪》,副主编,人民卫生出版社,201801
4. 《神经系统疾病动物模型》,主编,中国医药科技出版社,201706
5. 《合理使用治疗神经系统疾病的中药注射剂》,主编,中国医药科技出版社,201704
6. 《神经系统(高等学校教材，器官-系统整合教材，供基础、临床、预防、口腔医学类等专业用)》,副主编,人民卫生出版社,201703
7. 《脑血管病实验方法学》,主编,中国医药出版社,201404
重要奖项
1. 缺血性脑卒中非药物防治新技术的创研与应用 中华医学会科技奖 一等奖 201912
2. 活络益脑法（方）及其演变方药治疗慢性脑供血不足的神经保护作用 中国中西医结合学会科技奖 二等奖 201908
3. 上肢远隔缺血适应新技术的建立及其防治缺血性脑卒中的临床应用 教育部高等学校科技进步奖 一等奖 2017
4. 缺血性中风中药注射剂合理使用的临床研究 中国中西医结合学会 二等奖 2009
5. 缺血性脑血管病的综合外科治疗体系的研究 中华医学科技奖 三等奖 2008