姓名：张小东 性别：男 职称：主任医师、教授 招生院所：附属朝阳医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：外科学（泌尿外）(博) 外科学（泌尿外）(硕) 研究方向名称：肾移植、排尿功能障碍、泌尿系肿瘤 电子信箱：zhangxiaodong@bjcyh.com


社会任职
1. 《中华泌尿外科杂志》常务编委、国际神经泌尿外科学会常委、西城区医疗事故鉴定委员会专家、中华医学会医疗事故鉴定委员会专家
2. 《Chinese Medical Journal》、《中华外科杂志》、《中华器官移植杂志》、《中华全科医师杂志》、《中华干细胞与移植杂志》、《移植杂志》等多种杂志编委，《国际移植与血液净化杂志》副总编
3. 中华医学会器官移植分会委员
4. 中国肾移植科学登记系统管理委员会副秘书长
5. 《The Journal of Urology 》编委
6. 北京医学会器官移植分会副主任委员
7. 中国医师协会器官移植分会委员
个人简历
1. 197810-198408:白求恩医科大学英语医学专业 学士
2. 198508-198808:白求恩医科大学泌尿外科学 硕士
3. 198809-198908:北京大学人民医院 住院医师
4. 199090-199409:北京大学人民医院泌尿外科 主治医师
5. 199409-199909:北京大学人民医院泌尿外科 副主任医师、副教授
6. 199909-200412:北京大学人民医院泌尿外科 主任医师、教授、科副主任
7. 201301-201904:朝阳医院泌尿外科 科主任
8. 201301-:朝阳医院泌尿肾病中心 中心主任
9. 201603-201803:首都医科大学泌尿外科学系 副主任
重要学术论文
1. Yongjun Quan, Hongen Lei, Wasilijiang Wahafu, Yuexin Liu, Hao Ping, Xiaodong Zhang*.Inhibition of autophagy enhances the anticancer effect of enzalutamide on bladder cancer. Biomedicine & pharmacotherapy. 2019,120:109490.SCI
2. Yansheng Li, Xin Zhang, Xiaoguang Zhou, Xiaodong Zhang*.LHPP suppresses bladder cancer cell proliferation and growth via inactivating AKT/p65 signaling pathway. Bioscience reports. 2019,39(7):BSR**.SCI
3. Jiawei Ji, Sujuan Feng, Yihang Jiang, Wei Wang, Xiaodong Zhang*.Prevalence and Risk Factors of BK Viremia and Clinical Impact of BK Virus Surveillance on Outcomes in Kidney Transplant Recipients: A Single-Center Cross-Sectional Study. Experimental and clinical transplantation. 2019,17(6):727-731.SCI
4. Xiaoguang Zhou, Peng Zhang, Hu Han , Hongen Lei , Xiaodong Zhang*.Hypermethylated in cancer 1 (HIC1) suppresses bladder cancer progression by targeting yes-associated protein (YAP) pathway. Journal of cellular biochemistry. 2019,120(4):6471-6481.SCI
5. ongjun Quan, Hongen Lei, Wasilijiang Wahafu, Yuexin Liu, Hao Ping, Xiaodong Zhang*.Inhibition of autophagy enhances the anticancer effect of enzalutamide on bladder cancer. Biomedicine & pharmacotherapy. 2019,120:109490.SCI
6. Hui Shan, Yong Yang, Xuhui Zhu, Xiuwu Han,Peng Zhang, Xiaodong Zhang*.FAM83H-AS1 is associated with clinical progression and modulates cell proliferation, migration, and invasion in bladder cancer. Journal of cellular biochemistry. 2019,120(3):4687-4693.SCI
7. Hui Shan, Yong Yang, Xuhui Zhu, Xiuwu Han,Peng Zhang, Xiaodong Zhang*.FAM83H-AS1 is associated with clinical progression and modulates cell proliferation, migration, and invasion in bladder cancer. Journal of cellular biochemistry. 2019,120(3):4687-4693.SCI
8. Yihang Jiang, Sujuan Feng, Jiawei Ji, Zhemin Lin, Xiaodong Zhang*.Persistent accumulation of circulating monocytic myeloid-derived suppressor cells contributes to post-infectious immunosuppression in renal transplant recipients with bacterial infection: A pilot study. Transplant Immunology. 2018,Epub ahead of print:Epub ahead of print.SCI
9. Sujuan Feng, Xiaosong Qian, Han Li, Xiaodong Zhang*.Combinations of elevated tissue miRNA-17-92 cluster expression and serum PSA as potential diagnostic biomarkers for prostate cancer. Oncology Letters. 2017,14(6):6943-6949.SCI
10. Bohan Fan, Kui Qiu, Yihang Jiang, Xiaopeng Hu, Hang Yin, Wei Wang, Liang Ren, Hang Liu, Wei Wang, Xiaodong Zhang*.Prograf produces more benefits for CYP3A5 low expression patients in early stage after kidney transplantation. Biomedicine & Pharmacotherapy. 2017,88:738-744.SCI
11. Xiaosong Qian, Sujuan Feng, Dawei Xie, Dalin Feng, Yihang Jiang, Xiaodong Zhang*.RecQ helicase BLM regulates prostate cancer cell proliferation and apoptosis. Oncology Letters. Oncology Letters. 2017,14(4):4206-4212.SCI
12. Wei Wang, Dawei Xie, Xiaopeng Hu, Hang Yin, Hang Liu, Xiaodong Zhang*.Effect of Hypothermic Machine Perfusion on the Preservation of Kidneys Donated After Cardiac Death: A Single-Center, Randomized, Controlled Trial.. Artificial Organs. 2017,41(8):753-758.SCI
13. Yang Zhao, Huiting Su, Xiaofei Shen, Junfeng Du*, Xiaodong Zhang*, Yong Zhao*.The immunological function of CD52 and its targeting in organ transplantation. Inflammation Research. 2017,66(7):571-578.SCI
14. Hui Chen#，Lianjun Zhang#，Peng Wang#，Huiting Su#，Wei Wang，Zhulang Chu，Lianfeng Zhang，Xiaodong Zhang*, Yong Zhao* .mTORC2 controls Th9 polarization and allergic airway inflammation. Allergy. 2017,72(10):1510-1520.SCI
15. Hu Han, Xiaoguang Zhou, Xiaosong Qian, Sujuan Feng, Long Tian*, Xiaodong Zhang*.Significant alterations of serum hormone levels in the spermatic vein plexus of patients with varicoceles. Andrologia. 2016,48(10):1108-1112.SCI
16. Huiting Su，Ning Na，Yong Zhao*, Xiaodong Zhang*.The biological function and significance of CD74 in immune diseases. Inflammation Research. 2016,66:209-216.
17. Liyang Wu，Hang Liu，Wei Liu，Han Li，Xiaodong Zhang*.Kidney transplantation after liver transplantation . Hepatobiliary and Pancreatic Diseases International. 2016,15(4):439-442.SCI
18. Sujuan Feng#，Jing Yang#，Wei Wang，Xiaopeng Hu，Hang Liu，Xiaosong Qian，Dalin Feng，Xiaodong Zhang*.Incidence and Risk Factors for Cytomegalovirus Infection in Patients With Kidney Transplantation: A Single-Center Experience . Transplantation Proceedings. 2016,48:2695-2699.SCI
19. Chen Yan#, Yundong Zhang#, Xinghui Wang，Shundong Geng，Tianyuan Wang, Mao Sun, Wei Liang, Weiqing Zhang, Xiaodong Zhang*, Heng Luo*.Tirucallane-type triterpenoids from the fruits of Phellodendron chinense Schneid and their cytotoxic activities. Fitoterapia. 2016,113:132-138.SCI
20. Han Hu, Yu Zexing Zhang Xiaodong.The Prevalence and Association of variococels on male patients with BPH and LUTS. Urology. 2016,90:97-100.SCI
21. Sujuan Feng, Xuhui Zhu, Bohan Fan, Dawei Xie, Tao Li, Xiaodong Zhang*.miR-19a-3p targets PMEPA1 and induces prostate cancer proliferation, migration and invasion. Molecular Medicine Reports. 2016,13（5）:4030-4038.SCI
22. Hu Han, Xiaoguang Zhou, Dongdong Fan, Long Tian,Xiaodong Zhang*.An Unusual Etiology for Hematospermia and Treatments That Were Successful. Urology. 2015,86(4）:740-743.SCI
23. 张小东、尹航、邱葵.Lower dosing of enteric-coated mycophenolate sodium. Int J Clin Pract. 2014,68:31-37.SCI
24. 王玮、张希诺、张小东.Effects of Bailing capsules for renal transplant recipients: a retrospective . Chinese Medical Journal . 2013,126（10）:1895-1899.SCI
25. 张小东.CYP3A基因多态性与肾移植后早期钙调磷酸酶抑制剂的应用 . 中华器官移植杂志. 2012,33（9）:519-522.核心期刊
26. 杨晓勇，李世海，任亮，王玮，尹航，刘航，胡小鹏，张小东*.肾移植后早期受者BK病毒DNA拷贝数的影响因素研究 . 中华器官移植杂志. 2012,33（8）:477-480.核心期刊
27. Hu XP, Yin H, Zhang XD*.Evaluation and treatment of marginal grafts with surgicaldiseases in kidney transplantation. Chin Med J (Engl). 2012,125(3):461-464.SCI
28. Wang W, Tian H, Yin H, Liu H, Zhang XD*. Attitudes toward organ donation in China. Chin Med J (Engl). 2012,125(1):56-62.SCI
29. Hu XP, Liu Y, Zhang XD*.The organ donation in China. Chin Med J (Engl). 2012,125(21):3912-3.SCI
30. Wang W, Yin H, Li XB, Hu XP, Yang XY, Liu H, Ren L, Wang Y, Zhang XD*.A Retrospective Comparison of the Efficacy and Safety in Kidney Transplant Recipients with Basiliximab and anti-thymocyte globulin. Chin Med J (Engl). 2012,125(6):1135-40.SCI
31. Wang W, Li XB, Yin H, Yang XY, Liu H, Ren L, Hu XP, Wang Y, Zhang XD*.Factors affecting the long-term renal allograft survival. Chin Med J (Engl). 2011,124(8):1181-4.SCI
32. 王玮，尹航，胡小鹏，李晓北，杨晓勇，任亮，王勇，张小东*.生理盐水替代HTK保存液保存活体供肾的临床研究. 器官移植. 2011,02（5）:269-272.核心期刊
33. Yao QC, Wang W, Li XB, Yin H, Zhang XD*.Expression characteristics of major histocompatibility complex class I-related chain A antibodies and immunoadsorption effect in sensitized recipients of kidney transplantation. Chin Med J. 2011,124:669-72.SCI
34. Yin H, Wan H, Hu XP, Li XB, Wang W, Liu H, Ren L, Zhang XD*.Rituximab induction therapy in highly sensitized kidney transplant recipients. Chin Med J (Engl). 2011,124(13):1928-32.SCI
35. Li SH, Wang W, Hu XP, Yin H, Ren L, Yang XY, Liu H, Zhang XD*.Monitoring immune function after rapid corticosteroid reduction in kidney transplant recipients. Chin Med J. 2011,124:679-82.SCI
36. 田辉，王玮，尹航，乔永萍，姚庆春，刘航，张小东*.“公众对器官捐献态度”的问卷结果分析 . 中华器官移植杂志. 2011,32（12）:726-729.核心期刊
37. 王玮，尹航，李晓北，杨晓勇，任亮，刘航，张鹏，胡小鹏，王勇，张小东*.肾移植术后并发双侧自体肾盂和输尿管移行细胞癌16例 . 中华器官移植杂志. 2011,32（8）:474-476.核心期刊
38. 张小东，李晓北，杨毅*，张际青，刘航.致敏肾移植受者主要组织相容性复合物Ⅰ类链相关基因A抗体表达对预后的影响 . 中华肾脏病杂志. 2011,27（2）:91-95.核心期刊
39. 贾佳熹，张小东*.活体亲属肾移植患者HLA配型配合率的分析 . 国际检验医学杂志. 2011,32（16）:1809-1813.核心期刊
40. Li S, Wang W, Hu X, Ren L, Yin H, Yang X, Liu H, Zhang X*.The effects of early rapid corticosteroid reduction on cell-mediated immunity in kidney transplant recipients. Transpl Immunol. 2011,24(2):127-30.SCI
41. 张际青,尹航,胡小鹏,任亮,王勇,张小东（通讯作者）.腹膜外入路治疗移植肾周淋巴囊肿一例. 中华器官移植杂志. 2010,31(3):186.核心期刊
42. 张际青,张小东（通讯作者）.睾丸扭转诊治现状. 临床泌尿外科杂志. 2010, 25(1): 61-64.核心期刊
43. 王玮，刘航，尹航，李晓北，杨晓勇，任亮，胡小鹏，王勇，张小东.免疫吸附在高致敏肾移植受者中的应用. 中华医学杂志. 2010,36:2532-2535.核心期刊
44. 张小东, 李晓北, 张际青, 杨毅, 尹航, 胡小鹏, 任亮, 王玮刘航 杨晓勇.致敏肾移植受者抗MICA抗体的表达对术后早期排斥反应和肾功能的影响. 中华器官移植杂志. 2010,31 (6) :348-351.核心期刊
45. Yang Y, Ren L, Zhang Y, Liu H, Cao B, Zhang XD*.Changes in biochemical parameters on the first day after kidney transplantation: risk factors for nosocomial infection?. Chin Med J. 2010,123:563-8.SCI
46. Zhang J, Zhang X*, Liu L, Tong W.Value of CYP3A5 Genotyping on Determining Initial Dosages of Tacrolimus for Chinese Renal Transplant Recipients. Transplant Proc. 2010,42(40):3459-64.SCI
47. Hu X, Ren L, Yin H, Zhang X*.Signal Transducer and Activator of Transcription 1 and Matrix Metalloproteinase 3 Genetic Expression and Clinical Significance on Urothelial Tumors After Renal Transplantation. Transplant Proc. 2010,42:2534-7.SCI
48. Zhang J, Hu X, Wang W, Li X, Hang Y, Zhang X*.Role of multidetector-row computed tomography in evaluation of living renal donors. Transplant Proc. 2010,42:3433-6.SCI
49. Yang Yi, Zhangxiaodong*.Changes in biochemical parameters on the first day after kidney transplantation: risk factors for nosocomial infection?. Chin Med J. 2010,5:563-568.SCI
50. Hu Xiaopeng, Zhangxiaodong*.Signal Transducer and Activator of Transcription 1 and Matrix. Transplantation Proceeding. 2010,7:2534-2537.SCI
51. 张小东,胡小鹏,王勇,尹航，王玮,李晓北,刘航.153例亲属活体供肾移植的临床观察. 中国医学科学院学报. 2009,31(3): 300–302.核心期刊
52. 张际青,张小东（通讯作者）.活体供肾肾移植解剖学基础. 中国修复重建外科杂志. 2009,23(9) :1138-1142.核心期刊
53. Zhang X, Ren L, Hu X, Wang W, Yin H, Liu H, Zhang Y.Gene profiling of cyclosporin-enhanced transitional cell carcinoma in rat model. Transplant Proc. 2009,41(10):4369-4372.SCI
54. 张小东,张际青,尹航,王玮,胡晓鹏,任亮,杨晓勇,刘航,王勇.CYP3A5基因型对肾移植受者术后早期血他克莫司浓度的影响. 中华器官移植杂志. 2009,30(12):717-721.核心期刊
55. 张际青,胡小鹏,尹喜,黄涛，任亮,尹航,王玮,王勇,张小东（通讯作者）.多层螺旋CT在活体供肾术前评估中的作用. 中华器官移植杂志. 2009,30(7）: 419-421.核心期刊
56. 张际青,胡小鹏,孔秀珍,苟举民,刘家辉,张小东（通讯作者）.睾丸扭转反复误诊致睾丸坏死1例并文献复习. 中华男科学杂志. 2009,15(5):445-448.核心期刊
57. 张小东，王玮，胡小鹏，尹航.多发性囊肿肾作为供肾移植一例. 中华器官移植杂志. 2008,29(12):757.核心期刊
58. 李强，张小东（通讯作者）.特发性肾静脉血栓形成一例. 中华外科杂志. 2008,46(11):880.核心期刊
59. 张小东,王玮,胡小鹏,尹航,张鹏,王勇.肾移植受者肾结石的诊治分析. 中华外科杂志. 2008, 46(5):397-398.核心期刊
60. Zhang XD, Hu XP, Yin H, Wang W, Zhang X, Ma LL, Wang Y.Aspergillus pneumonia in renal transplant recipients. Chin Med J (Engl). 2008,121(9):791-794..SCI
61. 张小东,尹航,张宁,张勇,杨勇.Studer回肠膀胱的远期排尿功能和并发症的临床研究. 中华外科杂志. 2008,26(20):1536-1538.核心期刊
62. 张小东,胡小鹏,王玮,尹航,张鑫,马麟麟,王勇.肾移植术后并发肺曲霉病的诊治三例. 中华器官移植杂志. 2008, 568-569: 29(9).核心期刊
63. 徐涛，张小东，王晓峰，黄晓波，张晓鹏，侯树坤.膀胱出口梗阻患者充盈性膀胱测压参数的重测信度评价. 中华泌尿外科杂志. 2006,27(5):304-306.核心期刊
64. 王玮，张小东，马麟麟，吕月平，胡小朋，张鹏，王勇，管德林.肾移植中他克莫司的血药浓度与多药耐药基因多态性的关系. 中华医学杂志. 2005,85(46):3277-3280.核心期刊
65. 张小东，许克新，王晓峰，侯树坤.TURP在前列腺癌诊治中的作用评价. 中华泌尿外科杂志. 2005,26(5):308-310.核心期刊
66. 张小东.前列腺癌睾丸转移一例报告. 中华泌尿外科杂志. 2005,26(5):330.核心期刊
主编或副主编的著作/译著
1. 《肾移植临床用药》,主编,人民卫生出版社,201705
2. 《移植肾病理诊断》,主编,人民卫生出版社,201604
3. 《肾移植治疗学》,主编,人民卫生出版社,200908
4. 《肾移植诊疗学》,主译,人民卫生出版社,200710
5. 《门诊泌尿妇科学》,主编,人民卫生出版社,2005
6. 《斯密思泌尿外科学》,主编,人民卫生出版社,2004
7. 《肿瘤治疗学》,主编,人民卫生出版社,2001
8. 《尿动力学》,主编,人民卫生出版社,2000
重要奖项
1. 北京医学科技奖 高致敏患者肾移植的系统化治疗和临床应用 三等奖 2019
2. 中华医学科技奖 肾移植的规范化治疗 一等奖 2012