姓名：郑乐民 性别：男 职称：研究员、教授 招生院所：附属天坛医院 招生类型：科学学位(博) 科学学位(硕) 招生专业：病理学与病理生理学(博) 病理学与病理生理学(硕) 研究方向名称：脂代谢与动脉粥样硬化 电子信箱：leminzheng@163.com


社会任职
个人简历
1. 199409-199807:北京师范大学 本科
2. 199807-200007:中国科学院感光化学所 科研管理
3. 200008-200505:克利夫兰医院/克利夫兰州立大学 博士
4. 200503-200710:PrognostiX Inc. 克利夫兰医院所属 研究科学家
5. 200711-201807:北京大学心血管所 研究员
重要学术论文
1. Jingxuan Li#,Yingyu Chen#,Jianing Gao,Yue Chen,Changping Zhou,Xin Lin,Changjie Liu, Mingming Zhao,Yangkai Xu,Liang Ji,Zongzhe Jiang,Bing Pan *,Lemin Zheng*,.Eva1a ameliorates atherosclerosis by promoting re-endothelialization of injured arteries via Rac1/Cdc42/Arpc1b.. Cardiovascular Research. 2020,online:ahead of print.SCI
2. Li J, Zhou C, Xu H, Brook RD, Liu S, Yi T, Wang Y, Feng B, Zhao M, Wang X, Zhao Q, Chen J, Song X, Wang T, Liu S, Zhang Y, Wu R, Gao J, Pan B, Pennathur S, Rajagopalan S, Huo Y, Zheng L*, Huang W*. Ambient Air Pollution is Associated with High-Density Lipoprotein Dysfunction in Healthy Adults. Arterioscler Thromb Vasc Biol. 2019,39(3):513-522.SCI
3. Zhan R, Zhao M, Zhou T, Chen Y, Yu W, Zhao L, Zhang T, Wang H, Yang H, Jin Y, He Q, Yang X, Guo X, Willard B, Pan B, Huang Y, Chen Y, *Chui D, *Lemin Zheng. .Dapsone protects brain microvascular integrity from high-fat diet induced LDL oxidation.. Cell Death & Disease. . 2018,9(6):683.SCI
4. Lv Z,Ma Z,Xu Z,Feng C,Yang Y,Liao Q,Wang X,Zheng L,*Hongbing Fu..Intracellular near-Infrared Microlaser Probes Based on Organic. ACS Appl Mater Interfaces.. 2018,10(6):32981-32987.
5. Liu D, Ji L, Zhao M, Wang Y, Guo Y, Li L, Zhang D, Xu L, Pan B, Su J, Xiang S, Pennathur S, Li J, Gao J, Liu P, *Willard B, Lemin Zheng*.Lysine glycation of apolipoprotein A-I impairs its anti-inflammatory function in type 2 diabetes mellitus. J Mol Cell Cardiol. 2018,122:47-57.SCI
6. Dong Z, Shi H, Zhao M, Zhang X, Huang W, Wang Y, Lemin Zheng, Xian X, Liu G*..Loss of LCAT activity in the golden Syrian hamster elicits pro-atherogenic dyslipidemia and enhanced atherosclerosis.. Metabolism. 2018,83:245-255.SCI
7. Ke Y, Li D, Zhao M, Liu C, Liu J, Zeng A, Shi X, Cheng S, Pan B, *Lemin Zheng, *Hong H..Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress.. Free Radic Biol Med. . 2018,116:88-100..SCI
8. Wang Y, Meng R, Song H, Liu G, Hua Y, Cui D, Lemin Zheng, Feng W, Liebeskind DS, Fisher M, Ji X..Remote Ischemic Conditioning May Improve Outcomes of Patients With Cerebral Small-Vessel Disease.. Stroke.. 2017,48(11):3064-3072..SCI
9. Lu J, Chen B, Chen T, Guo S, Xue X, Chen Q, Zhao M, Xia L, Zhu Z, *Lemin Zheng, *Yin H..Comprehensive metabolomics identified lipid peroxidation as a prominent feature in human plasma of patients with coronary heart diseases. . Redox Biol. . 2017,12:899-907.SCI
10. Dan He, Mingming Zhao, Congying Wu, Wenjing Zhang, Chenguang Niu, Baoqi Yu, Jingru Jin, Liang Ji, Belinda Willard, Anna V. Mathew, Y. Eugene Chen, Subramaniam Pennathur, Huiyong Yin, Yuan He, *Bing Pan, *Lemin Zheng. .Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1.. Redox Biol.. 2017,15:228-242.SCI
11. Niu C, Wang X, Zhao M, Cai T, Liu P, Li J, Willard B, Zu L, Zhou E, Li Y, Pan B, *Yang F, *Lemin Zheng. .Macrophage Foam Cell-Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion.. J Am Heart Assoc. . 2016,17:5(10).SCI
12. Wang Y, Zhou XM, Ma X, Du Y, Lemin Zheng, Liu P. .Construction of Nanodroplet/Adiposome and Artificial Lipid Droplets. . ACS Nano.. 2016,10(3):3312-22.SCI
13. Pan B, Kong J, Jin J, Kong J, He Y, Dong S, Ji L, Liu D, He D, Kong L, Jin D, Willard B, Pennathur S, *Lemin Zheng..A Novel Anti-inflammatory Mechanism of High Density Lipoprotein Through Up-regulating Annexin A1 in Vascular Endothelial Cells. . BBA-Molecular and Cell Biology of Lipids.. 2016,1861(6):501-12.SCI
14. Mingli Peng, Houli Li, Zhiyi Luo, Jian Kong, Yinsheng Wan, *Zheng Lemin, Qinlu Zhang, Hongxin Niu, Alphons Vermorken, Wim Van de Ven, Chao Chen, Xikun Zhang, Fuqiang Li, Lili Guo, Yali Cui*..Dextran-coated superparamagnetic nanoparticles as potential cancer drug carriers in vivo.. Nanoscale.. 2015,7(25):11155-62.SCI
15. Zu L, Ren C, Pan B, Zhou B, Zhou E, Niu C, Wang X, Zhao M, Gao W, *Guo Lijun, *Zheng Lemin..Endothelial microparticles after antihypertensive and lipid-lowering therapy inhibit the adhesion of monocytes to endothelial cells.. International Journal of Cardiology. . 2015,202:756-759.SCI
16. Pan B, Yu B, Ren H, Willard B, Pan L, Zu L, Shen X, Ma Y, Li X, Niu C, Kong J, Kang S, Chen Y. E, Pennathur S, *Zheng Lemin..High Density Lipoprotein (HDL) Nitration and Chlorination Catalyzed by Myeloperoxidase Impairs Its Effects in Promoting Endothelial Repair.. Free Radical Biology & Medicine. . 2013,60:272-81.SCI
17. Lemin Zheng, Nukuna B, Brennan M, Sun M, Goormastic M, Settle M, Schmitt D, Fu X, Thomson L, Fox P, Ischiropoulos H, Smith J, Kinter M, and Hazen S..Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease. Journal of Clinical Investigation.. 2004,114:529-541.SCI
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