姓名：蒋宏峰 性别：男 职称：教授 招生院所：附属安贞医院 招生类型：科学学位(博) 科学学位(硕) 招生专业：病理学与病理生理学(博) 病理学与病理生理学(硕) 研究方向名称：心血管病因学，代谢组学，分子诊断 电子信箱：hfjiang@ccmu.edu.cn


社会任职
1. 美国生物化学与分子生物学学会 (ASBMB)专业会员
2. 美国质谱学会 (ASMS)专业会员
3. Biomarkers Journal编委
4. 中国生物化学与分子生物学会脂质与脂蛋白专业委员会青年委员会常务委员
5. 中国病理生理学会代谢小分子专业委员会委员
个人简历
1. 199509-200006:苏州大学 本科生
2. 200109-200701:北京大学 研究生
3. 200709-201108:美国哥伦比亚大学 博士后研究员
4. 201109-201806:美国哥伦比亚大学 副研究员
5. 201709-:首都医科大学 教授
重要学术论文
1. LS Huang, JJ Yuen, MJ Trites, A Saha, CT Epps, Y Hu, S Kerolle, SA Lee, Jiang H, Goldberg IJ, Blaner WS, Clugston RD*.Dietary macronutrient composition determines the contribution of DGAT 1 to alcoholic steatosis. Alcoholism: Clinical and Experimental Research. 2018,42(12):2298-2312.SCI
2. E Spiegler, YK Kim, B Hoyos, S Narayanasamy, H Jiang, N Savio, Curley RW Jr, Harrison EH, Hammerling U, Quadro L*.β-apo-10'-carotenoids support normal embryonic development during vitamin A deficiency. Sci Rep. 2018,8(1):88834.SCI
3. Blaner WS, Gao MA, Jiang H, Dalmer TR, Hu XJ, Ginsberg HN, Clugston RD*.Chronic alcohol consumption decreases brown adipose tissue mass and disrupts thermoregulation: a possible role for altered retinoid signaling. Sci Rep. 2017,7:43474.SCI
4. hang H, Shi J, Hachet MA, Xue C, Bauer RC, Jiang H, Li W, Tohyama J, Millar J, Billheimer J, Phillips MC, Razani B, Rader DJ, Reilly MP*.CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages. ATVB. 2017,37(11):2156-2160.SCI
5. Ziosi M, Di Meo I, Kleiner G, Gao XH, Barca E, Sanchez-Quintero MJ, Tadesse S, Jiang H, Qiao C, Rodenburg RJ, Scalais E, Schuelke M, Willard B, Hatzoglou M, Tiranti V, Quinzii CM.Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway. EMBO Mol Med. 2017,9(1):96-111.SCI
6. Bowden JA*, Heckert A, Ulmer CZ, Jones CM, Jiang H, Zhao XH, Zhou S.Harmonizing Lipidomics: NIST Interlaboratory Comparison Exercise for Lipidomics using Standard Reference Material 1950 Metabolites in Frozen Human Plasma. Journal of Lipid Research. 2017,58(12):2275-2288.SCI
7. Ji R, Akashi H, Drosatos K, Liao X, Jiang H, Kennel PJ, Brunjes DL, Castillero E, Zhang X, Deng LY, Homma S, George IJ, Takayama H, Naka Y, Goldberg IJ, Schulze PC*.Increased de novo ceramide synthesis and accumulation in failing myocardium. JCI Insight. 2017,4:e82922.
8. Wang C, Liu W, Yao L, Zhang X, Zhang X, Ye C, Jiang H, He J, Zhu Y, Ai D*.Hydroxyeicosapentaenoic acids and epoxyeicosatetraenoic acids attenuate early occurrence of nonalcoholic fatty liver disease. Br J Pharmacol. 2017,174(14):2358-2372.SCI
9. Guo H, Foncea R, O'Byrne SM, Jiang H, Zhang Y, Deis JA, Blaner WS, Bernlohr DA, Chen X*.Lipocalin 2: a regulator of retinoid homeostasis and retinoid-mediated thermogenic activation in adipose tissue. J Biol Chem. 2016,291(21):11216-29.SCI
10. Furst JR, Bandeira LC, Fan WW, Agarwal S, Nishiyama KK, McMahon DJ, Dworakowski E, Jiang H, Silverberg SJ, Rubin MR.Advanced Glycation Endproducts and Bone Material Strength in Type 2 Diabetes. J Clin Endocrinol Metab. 2016,101(6):2502-10.SCI
11. Lee SA, Yuen JJ, Jiang H, Kahn BB, Blaner WS.Adipocyte-specific over-expression of retinol-binding protein 4 (RBP4) causes hepatic steatosis in mice. Hepatology. 2016,64(5):1534-46.SCI
12. Alsahli A, Kiefhaber K, Gold T, Muluke M, Jiang H, Cremers S, Schulze-Späte U*.Palmitic Acid Reduces Circulating Bone Formation Markers in Obese Animals and Impairs Osteoblast Activity via C16-Ceramide Accumulation. Calcif Tissue Int. 2016,98(5):511-9.SCI
13. Takeda K, Sriram S, Derryn Chan XH, Ong WK, Yeo CR, Tan B, Lee SA, Kong KV, Hoon S, Jiang H, Yuen JJ, Perumal J, Agrawal M, Vaz C, So J, Shabbir A, Blaner WS, Olivo M, Han W, Tanavde V, Toh SA, Sugii S*.Retinoic Acid Mediates Visceral-specific Adipogenic Defects of Human Adipose-derived Stem Cells. Diabetes. 2016,65(5):1164-78.SCI
14. Muluke M, Gold T, Kiefhaber K, Al-Sahli A, Celenti R, Jiang H, Cremers S, Van Dyke T, Schulze-Späte U*.Diet-Induced Obesity and Its Differential Impact on Periodontal Bone Loss. J Dent Res. 2016,95(2):223-9.SCI
15. Wang CX, Jiang H, Yuen JJ, Lee SA, Narayanasamy S, Curley RW Jr, Harrison EH, Blaner WS.Actions of β -apo-carotenoids in differentiating cells: differential effects in P19 cells and 3T3-L1 adipocytes. Arch Biochem Biophys. 2015,572:2-10.SCI
16. Kraus BJ, Sartoretto JL, Polak P, Hosooka T, Shiroto T, Eskurza I, Lee SA, Jiang H, Michel T, Kahn BB*. .Novel role for retinol-binding protein 4 in the regulation of blood pressure. FASEB J. 2015,29(8):3133-40.SCI
17. He J, Xu C, Kuang J, Liu Q, Jiang H, Mo L, Geng B, Xu G*.Thiazolidinediones attenuate lipolysis and ameliorate dexamethasone-induced insulin resistance. Metabolism. 2015,647(7):826-36.SCI
18. O'Mahony F, Wroblewski K, O'Byrne SM, Jiang H, Clerkin K, Benhammou J, Blaner WS, Beaven SW*.Liver X receptors balance lipid stores in hepatic stellate cells through Rab18, a retinoid responsive lipid droplet protein. Hepatology. 2015,62(2):615-26.SCI
19. Yuen JJ, Lee SA, Jiang H, Brun PJ, Blaner WS*.DGAT1-deficiency affects the cellular distribution of hepatic retinoid and attenuates the progression of CCl4-induced liver fibrosis. Hepatobiliary Surg Nutr. 2015,4(3):184-96.SCI
20. Wang CX, Jiang H, Yuen JJ, Lee SA, Narayanasamy S, Curley RW Jr, Harrison EH, Blaner WS.Actions of β-apo-carotenoids in differentiating cells: differential effects in P19 cells and 3T3-L1 adipocytes. Arch Biochem Biophys. 2015,572:2-10.SCI
21. Takeda Y, Kang HS, Lih FB, Jiang H, Blaner WS, Jetten AM*.Retinoid acid-related orphan receptor γ, RORγ, participates in diurnal transcriptional regulation of lipid metabolic genes. Nucleic Acids Res. 2014,42(16):10448-59.SCI
22. Wei J, Ferron M, Clarke CJ, Hannun YA, Jiang H, Blaner WS, Karsenty G*.Bone-specific insulin resistance disrupts whole-body glucose homeostasis via decreased osteocalcin activation. J Clin Invest. 2014,124(4):1-13.SCI
23. Yoshida K, Reeves C, Vink J, Kitajewski J, Wapner R, Jiang H, Cremers S, Myers K*.Cervical collagen network remodeling in normal pregnancy and disrupted parturition in Antxr2 deficient mice. J Biomech Eng. 2014,136(2):**-8.SCI
24. Liu L, Trent CM, Fang X, Son NH, Jiang H, Blaner WS, Hu Y, Yin YX, Farese RV Jr, Homma S, Turnbull AV, Eriksson JW, Hu SL, Ginsberg HN, Huang LS, Goldberg IJ*.Cardiomyocyte-specific loss of diacylglycerol acyltransferase 1 (DGAT1) reproduces the abnormalities in lipids found in severe heart failure. J Biol Chem. 2014,289(43):29881-91.SCI
25. Lee SA, Jiang H, Trent CM, Yuen JJ, Narayanasamy S, Curley RW Jr, Harrison EH, Goldberg IJ, Maurer MS, Blaner WS.Cardiac dysfunction in β -carotene-15,15'-dioxyge nase-deficient mice is associated with altered retinoid and lipid metabolism. Am J Physiol Heart Circ Physiol. 2014,307(11):H1675-84.SCI
26. Jiang H, Ai D, Westerterp M, Murphy AJ, Wang M, Ganda A, Abramowicz S, Welch C, Almazan F, Zhu Y, Miller YI, Tall AR.Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis. Circulation Research. 2014,114(10):1576-84.SCI
27. Jiang H, Westerterp M, Wang C, Zhu Y, Ai D.Macrophage mTORC1 disruption reduces inflammation and insulin resistance in obese mice. Diabetologia. 2014,57(11):2393-404.SCI
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