姓名：段钟平 性别：男 职称：主任医师、教授 招生院所：北京佑安医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：内科学（传染病）(博) 内科学（传染病）(硕) 研究方向名称：肝病基础与临床研究 电子信箱：duan2517@sohu.com


社会任职
1. 吴阶平医学基金会肝病医学部主任
2. 全国疑难及重症肝病攻关协作组组长
3. 北京医药科学技术发展协会主席
4. 首都医科大学传染病学系副主任
5. 南昌大学客座教授
6. 中华医学会肝病学分会遗传代谢性肝病协作组组长
7. 中华医学会肝病学分会终末期肝病学组组长
8. 首都医科大学肝病转化医学研究所所长
个人简历
1. 198809-199108:兰州医学院　　 硕士研究生
2. 199109-199508:山东胜利油田总医院肝病研究所 所长
3. 199509-199808:首都医科大学 博士研究生
4. 200305-201806:首都医科大学附属北京佑安医院 主任、副院长
5. 201806-201902:首都医科大学附属北京佑安医院 主任医师、教授
重要学术论文
1. Qian X, Zheng S, Wang L, Yao M, Guan G, Wen X, Zhang L, Xu Q, Chen X, Zhao J, Duan Z*, Lu F.Exploring the Diagnostic Potential of Serum Golgi Protein 73 for Hepatic Necroinflammation and Fibrosis in Chronic HCV Infection with Different Stages of Liver Injuries. Dis Markers. 2019,17:**.SCI
2. Zhao M, Zou H, Chen Y, Zheng S, Duan Z*.Efficacy of antepartum administration of hepatitis B immunoglobulin in preventing mother-to-child transmission of hepatitis B virus. J Viral Hepat. 2019,26(9):1059-1065.SCI
3. Bai L, Chen Y, Zheng S, Ren F, Kong M, Liu S, Han Y, Duan Z*.Phenotypic switch of human and mouse macrophages and resultant effects on apoptosis resistance in hepatocytes. Innate Immun. 2019,25(3):176-185.SCI
4. Han W, Duan Z*.Roles of exosomes in liver metastases: Novel diagnosis and treatment choices. J Cell Physiol. 2019,234(12):21588-21600.SCI
5. Wei L, Omata M, Lim YS, Xie Q, Hou JL, Jia J, Hedskog C, Martin R, Doehle B, Yang J, De-Oertel S, Massetto B, Kersey K, Brainard DM, Svarovskaia E, Mo H, Han KH, Mizokami M, Duan Z*.HCV phylogenetic signature and prevalence of pretreatment NS5A and NS5B NI-Resistance associated substitutions in HCV-Infected patients in Mainland China. Antiviral Res. 2018,158:178-184.SCI
6. Han W, Wu Q, Zhang X, Duan Z*.Innovation for hepatotoxicity in vitro research models: A review. J Appl Toxicol. 2018,39(1):146-162.SCI
7. Yao J, Zhou X, Wang H, Yuan L, Chen Y, Duan Z*.Persistently Increased Resting Energy Expenditure Predicts Short-Term Mortality in Patients with Acute-on-Chronic Liver Failure. Ann Nutr Metab. 2018,73(1):2-9.SCI
8. Bai L, Liu X, Zheng Q, Kong M, Zhang X, Hu R, Lou J, Ren F, Chen Y, Zheng S, Liu S, Han YP, Duan Z*, Pandol SJ.M2-like macrophages in the fibrotic liver protect mice against lethal insults through conferring apoptosis resistance to hepatocytes. Sci Rep. 2017,7(1):10518.SCI
9. Gao S, Joshi SS, Osiowy C, Chen Y, Coffin CS, Duan ZP*.Chronic hepatitis B carriers with acute on chronic liver failure show increased HBV surface gene mutations, including immune escape variants. Virol J. 2017,Oct 24;14(1):203.SCI
10. Shi H, Shi H, Ren F, Chen D, Chen Y, Duan Z*.Naringin in Ganshuang Granule suppresses activation of hepatic stellate cells for anti-fibrosis effect by inhibition of mammalian target of rapamycin. J Cell Mol Med. 2017,Mar;21(3):500-509.SCI
11. Pan CQ, Duan Z, Dai E, Zhang S, Han G, Wang Y, Zhang H, Zou H, Zhu B, Zhao W, Jiang H; China Study Group for the Mother-to-Child Transmission of Hepatitis B.Tenofovir to Prevent Hepatitis B Transmission in Mothers with High Viral Load. N Engl J Med.. 2016,374(24）:2324-34.SCI
12. Yao J, Zhou L, Hua X, Kong M, Chen Y, Duan Z*.Effects of nucleos(t)ide analogs on body composition in HBV-infected men: An age- and BMI-matched, cross-sectional study. Nutrition. 2016,16:30041-7.SCI
13. Ren F, Zhang L, Zhang XY, Shi HB, Wen T, Bai L, Zheng SJ, Chen Y, Chen DX, Li LY, Duan ZP*. Inhibition of glycogen synthase kinase3β promotes autophagy to protect mice from acute liver failure mediated by peroxisome proliferator-activated receptorα. Cell Death & Disease. 2016,7:e2151.SCI
14. Shi HB, Sun HQ, Shi HL, Ren F, Chen Y, Chen DX, Lou JL, Duan ZP*..Autophagy in anti-apoptotic effect of augmenter of liver regeneration in HepG2 cells.. World J Gastroenterol.. 2015,21（17）:5250-8.SCI
15. Wang Y, Liu S, Chen Y, Zheng S, Zhou L, Lu F, Duan Z*..Delayed Reduction of Hepatitis B Viral Load and Dynamics of Adefovir-Resistant Variants during Adefovir plus Entecavir Combination Rescue Therapy.. Int J Med Sci.. 2015,12（5）:416-22.SCI
16. Ren F, Zhou L, Zhang X, Wen T, Shi H, Xie B, Li Z, Chen D, Wang Z, Duan Z*. .Endoplasmic reticulum stress-activated glycogen synthase kinase 3β aggravates liver inflammation and hepatotoxicity in mice with acute liver failure.. Inflammation.. 2015,38(3):1151-65.SCI
17. Zheng SJ, Qu F, Li JF, Zhao J, Zhang JY, Liu M, Ren F, Chen Y, Zhang JL, Duan ZP*..Serum sphingomyelin has potential to reflect hepatic injury in chronic hepatitis B virus infection.. Int J Infect Dis.. 2015,33:149-55.SCI
18. Li JF, Qu F, Zheng SJ, Ren F, Wu HL, Liu M, Ren JY, Chen Y, Duan ZP*, Zhang JL..Plasma sphingolipids: potential biomarkers for severe hepatic fibrosis in chronic hepatitis C.. Mol Med Rep. 2015,12(1):323-30.SCI
19. Zhu L, Kong M, Han YP, Bai L, Zhang X, Chen Y, Zheng S, Yuan H, Duan Z*..Spontaneous liver fibrosis induced by long term dietary vitamin D deficiency in adult mice is related to chronic inflammation and enhanced apoptosis.. Can J Physiol Pharmacol.. 2015,93(5):385-94.SCI
20. Zheng SJ, Liu S, Liu M, McCrae MA, Li JF, Han YP, Xu CH, Ren F, Chen Y, Duan ZP..Prognostic value of M30/M65 for outcome of hepatitis B virus-related acute-on-chronic liver failure.. World J Gastroenterol.. 2014,20(9):2403-22.SCI
21. Qu F, Zheng SJ, Wu CS, Jia ZX, Zhang JL, Duan ZP*..Lipidomic profiling of plasma in patients with chronic hepatitis C infection.. Anal Bioanal Chem.. 2014,406(2):555-64.SCI
22. Duan Z, Jia JD, Hou J, Lou L, Tobias H, Xu XY, Wei L, Zhuang H, Pan CQ..Current challenges and the management of chronic hepatitis C in mainland China.. J Clin Gastroenterol.. 2014,48(8):679-86.SCI
23. Li JF, Liu S, Ren F, Liu M, Wu HL, Chen Y, Zou HB, Bai L, Li Y, Zheng SJ, Duan ZP*..Fibrosis progression in interferon treatment-naive Chinese plasma donors with chronic hepatitis C for 20 years: a cohort study. Int J Infect Dis. . 2014,10(27):49-53.SCI
24. Duan Z, Jia JD, Hou J, Lou L, Tobias H, Xu XY, Wei L, Zhuang H, Pan CQ.Current Challenges and the Management of Chronic Hepatitis C in Mainland China. J Clin Gastroenterol.. 2014,48(8):679-86.SCI
25. Li JF, Qu F, Zheng SJ, Ren JY, Wu HL, Liu M, Liu H, Ren F, Chen Y, Zhang JL, Duan ZP*.Plasma sphingolipids as potential indicators of hepatic necroinflammation in patients with chronic hepatitis C and normal alanine aminotransferase level. PLoS One. 2014,9(4):e95095.
26. Liu M, Chen Y, Zheng S, Duan Z*,Zhang JY.Biotherapy for autoimmune liver diseases. Curr Pharm Biotechnol.. 2014,15(6):510-5.SCI
27. Qiu Q, Li Y, Duan XW, Yang LK, Chen Y, Li H, Wang L, Duan ZP*.Impact of a new reimbursement program on hepatitis B antiviral medication cost and utilization in beijing, china. PLoS One. 2014,9(10):e109652.SCI
28. Kong M, Zhu L, Bai L, Zhang X, Chen Y, Liu S, Zheng S, Pandol SJ, Han YP, Duan Z*.Vitamin D deficiency promotes nonalcoholic steatohepatitis through impaired enterohepatic circulation in animal model. Am J Physiol Gastrointest Liver Physiol. . 2014,307(9):G883-93.SCI
29. Wei L, Ren F, Zhang X, Wen T, Shi H, Zheng S, Zhang J, Chen Y, Han Y,Duan ZP*.Oxidative stress promotes D-GalN/LPS-induced acute hepatotoxicity by increasing glycogen synthase kinase 3β activity. . Inflamm Res.. 2014,63(6):485-94.SCI
30. Han YP, Kong M, Zheng S, Ren Y, Zhu L, Shi H, Duan Z .Vitamin D in liver diseases: from mechanisms to clinical trials. J Gastroenterol Hepatol. 2013,28:49-55.SCI
31. Zhao BB, Zheng SJ, Gong LL, Wang Y, Chen CF, Jin WJ, Zhang D, Yuan XH, Guo J, Duan ZP, He YW.T lymphocytes from chronic HCV-infected patients are primed for activation-induced apoptosis and express unique pro-apoptotic gene signature. PLoS One. 2013,8(10):e77008.SCI
32. Pan CQ, Zou HB, Chen Y, Zhang X, Zhang H, Li J, Duan Z*..Cesarean section reduces perinatal transmission of hepatitis B virus infection from hepatitis B surface antigen-positive women to their infants.. Clin Gastroenterol Hepatol.. 2013,11（10）:1349-55.SCI
33. Wang S, Zhang X, Ju Y, Zhao B, Yan X, Hu J, Shi L, Yang L, Ma Z, Chen L, Liu Y, Duan Z, Chen X, Meng S..MicroRNA-146a feedback suppresses T cell immune function by targeting Stat1 in patients with chronic hepatitis B.. J Immunol.. 2013,191（1）:293-301.SCI
34. Zou H, Chen Y, Duan Z, Zhang H, Pan C*.Virologic factors associated with failure to passive-active immunoprophylaxis in infants born to HBsAg-positive mothers. Journal of Viral Hepatitis. 2012,19(2):e18-e25.SCI
35. Yun Li , Xiao-Feng Li , Hua Guo , Jing-Dong Xu , Xiao-Hui Zhang , Li-Sheng Li , Xiao-Yan Feng ,Yue Zhang , Zhong-Ping Duan*, Jin-Xia Zhu. Colonic submucosal 5-HT3 receptor-mediated somatostatin-dependent secretoinhibitory pathway is suppressed in water-immersion restraint stressed rats.. European Journal of Pharmacology. 2011,656:94–100.SCI
36. Feng Ren, Zhongping Duan, Qiao Cheng，Xiuda Shen, Feng Gao, Li Bai, Jun Liu, Ronald W. Busuttil, Jerzy W. Kupiec-Weglinski, and Yuan Zhai..Inhibition of Glycogen Synthase Kinase 3 beta Ameliorates Liver Ischemia Reperfusion Injury by Way of an Interleukin-10-Mediated Immune Regulatory Mechanism . Hepatology. 2011,54:687-696.SCI
37. 陈煜，时红波，张帆，丁美，赵军，刘旭华，段钟平*.TLR2、TLR4和TLR9在慢性重型肝炎患者及肝衰竭大鼠中的表达. 世界华人消化杂志. 2010,18(13):1320-1325.核心期刊
38. Ren F, Chen Y, Wang Y, Yan Y, Zhao J, Ding M, Zhang J, Jiang Y, Zhai Y, Duan ZP*.Comparative serum proteomic analysis of patients with acute-on-chronic liver failure: alpha-1-acid glycoprotein maybe a candidate marker for prognosis of hepatitis B virus infection. Journal of Viral Hepatitis. 2010,17(11):816-824.SCI
39. 邹怀宾，陈煜，张华，段钟平*，李杰，庄辉，梁晓峰，Calvin Q. Pan.乙型肝炎病毒母婴传播及其阻断研究的现状与存在问题. 中华肝脏病杂志. 2010,18(7):556-558.核心期刊
40. 陈煜，时红波，张帆，丁美，赵军，刘旭华，段钟平*.慢性重型肝炎患者外周血单个核细胞中TLR2、TLR3和TLR9的mRNA表达 . 肝脏. 2010,15(4):244-246.核心期刊
41. 陈煜，李文，李卫红，张海燕，丁美，任锋，安威，段钟平*.过表达CCAAT增强子结合蛋白对人HepG2细胞代谢能力的影响. 中华肝脏病杂志. 2010,18(6):474-475.核心期刊
42. 段钟平*.重型肝炎及肝衰竭现代试验平台及其应用. 实用肝脏病杂志. 2009,12（1）:1-4.
43. 任锋，段钟平*.MALDI-TOF-MS技术应用于非肝癌肝病蛋白质组学的研究进展. 实用肝脏病杂志. 2009,12（1）:59-62.
44. 郑素军，陈鹏，段钟平*.siRNA在试验性急性肝衰竭中的治疗作用研究进展. 中华肝脏病杂志. 2009,17（3）:238-240.核心期刊
45. 段钟平*，张晶.重型肝炎及肝衰竭的人工肝个体化治疗. 中华肝脏病杂志. 2009,17（5）:324-325.核心期刊
46. 肖晋美，高虹，陈煜，郑素军，段钟平*.慢性重型肝炎患者血浆体外灌流对C3A细胞增殖功能的影响. 中华肝脏病杂志. 2009,17（3）:223-224.核心期刊
47. 段钟平*，陈煜.重型肝炎及肝衰竭研究的进展与展望. 中华肝脏病杂志. 2009,17（1）:10-11.核心期刊
48. 张晶，杨仙珊，李晓晴，赵鹏，丁美，张立洁，赵军，段钟平*.5-HT及其受体在大鼠肝再生中的作用. 山东医药. 2009,49（32）:5-7.核心期刊
49. 魏琳琳，郑素军，陈煜，赵军，丁美，段钟平*.N-乙酰半胱氨酸对C3A永生化肝细胞解毒代谢功能的影响. 世界华人消化杂志. 2008,16（23）:2610-2614.
50. 魏琳琳，陈煜，郑素军，丁美，赵军，段钟平*.N-乙酰半胱氨酸对C3A永生化肝细胞增殖和生物转化功能的影响. 肝脏. 2008,13（1）:27-29.
51. 刘旭华，孟艳英，陈煜，张立洁，王泰龄，段钟平*.采用免疫型肝硬化大鼠建立慢加急性肝衰竭模型方法的研究. 胃肠病学和肝病学杂志. 2008,17（10）:790-793.
52. 刘旭华，段钟平*，孙异临，赵丽莉，蔡青，鲁强，张晶，王泰龄.急性内毒素性肝衰竭大鼠肝细胞凋亡形态学观察. 首都医科大学学报. 2008,29（4）:38-42.
53. 段钟平，朱跃科*，陈 煜，单晶，刘芳，周莉，谢贤春，王宝恩，王融冰，陈红，辛绍杰.水飞蓟宾磷脂复合物防治脂肪肝的动物试验与临床观察. 实用肝脏病杂志. 2008,11（4）:218-221，266.
54. 段钟平*.请重视血液净化在肝病中的应用. 中国血液净化. 2008,7（12）:5-6，26.
55. 刘旭华，陈煜，王泰龄，闾军，张立洁，宋晨朝，张晶，段钟平*.人血白蛋白及D-氨基半乳糖、脂多糖联合诱导建立大鼠慢加急性肝衰竭模型. 中华肝脏病杂志. 2007,15（10）:771-775.
56. 刘旭华，段钟平*.慢加急性肝衰竭及其分子吸附再循环治疗. 中国血液净化. 2007,6（9）:324-327.
57. 张文中，刘旭华，赵军，陈煜，段钟平*.慢加急性肝衰竭大鼠血清TNF-α、白介素-10及肝细胞凋亡的动态变化. 中国血液净化. 2007,6（9）:496-499.
58. 张立洁，王泰龄*，刘旭华，祖可佳，孟欣，王跃，段钟平*.慢性重型乙型肝炎的病理形态学表现及诊断. 中华肝脏病杂志. 2007,15（5）:323-325.
59. 段钟平*，陈煜.人工肝技术的进展. 传染病信息. 2007,20(3):129-131.
60. 张晶，万华旭，段钟平*，苏桂平，韩大康，李 颖，韩靖，朱彦涛，赵军.血浆置换数学模型的建立和应用. 山东医药. 2007,47（19）:35-37.
61. 段钟平*，陈煜.终末期肝病的常见并发症及处理. 中华肝脏病杂志. 2007,15（6）:458-460.
62. 张晶，段钟平*，何金秋，张伦理，陈士彬，邹春毅，辛绍杰，武文芳，马斌荣，陈煜，孔明，刘梅，韩大康.人工肝治疗对重型肝病患者生存期的影响. 中华肝脏病杂志. 2006,14（9）:647-651.
63. 段钟平*，郑素军.人工肝技术的临床应用. 中华肝脏病杂志. 2006,14（9）:680-681.
64. Duan zhong-ping*，Zhao Xiu-ying,Huang De-zhuang,He Li-xiang,Chen Yu,Zhao Chun-hui,Zheng Bo-jian*..Rantes gene single nucleotide polymorphisms and expression in patients with chronic hepatitis B virus infection. Chinese Medical Journal. 2005,118（11）:909-914.SCI
65. Qing Liu,Zhong Ping Duan,Da Kang Ha,Stig Bengmark,Jelica Kurtovic,Stephen M. Riordan*.Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis. Hepotology. 2004,39(5):1441-1449.SCI
主编或副主编的著作/译著
1. 《传染病学》,主编,北京大学医学出版社,2015
2. 《全国肝病科普咨询专家规范化培训试题》,主编,中国医药科技出版社,201406
3. 《传染病学英文版》,主编,高等教育出版社,201205
4. 《疑难及重症肝病查房实录》,主编,中国医药科技出版社,201005
5. 《血液净化模式与临床应用》,副主编,北京科学技术出版社,200809
6. 《疑难及重症肝病临床诊疗100例》,主编,天津科学技术出版社,200703
7. 《实用人工肝及血液净化操作手册》,主编,中国医药科技出版社,200508
8. 《住院医师传染性疾病规范化培训教材》,副主编,人民卫生出版社,200312
9. 《实用SARS学》,副主编,人民卫生出版社,200311
10. 《人工肝脏治疗学》,主编,中国医药科技出版社,200206
重要奖项
1. 肝功能衰竭综合防治体系的研究与临床应用 河北医学科技奖 一等奖 201412
2. 吴阶平医学奖 吴阶平医学奖 医药创新奖 201310
3. 重型肝炎肝衰竭临床诊疗关键技术及相关机制研究 首都十大疾病科技公关创新型科技成果奖 201211
4. 中药连花清瘟治疗流行性感冒研究 国家科技进步奖二等奖 201112
5. 病毒性肝炎规范化诊断及治疗的关键技术研究 中华医学科技二等奖 200812
6. 北京市病毒性肝炎临床诊断及治疗的一体化研究 北京市科学技术一等奖 200712
7. 血浆置换计算分析系统软件 国家版权局专利，项目负责人 200508
8. 肝纤维化及早期肝硬化血清学诊断体系的建立和应用研究 丰台区科技进步二等奖 200503
9. 中国重型肝炎临床应用指南及规范研究 北京市科技进步三等奖 200403
10. 传染病及重点传染病防治知识培训系列教材 丰台区科学技术奖 200403
11. 慢性乙型肝炎临床与病理诊断的对照研究 北京市科技进步三等奖 200212