姓名：范志朋 性别：男 职称：研究员、教授 招生院所：附属口腔医院 招生类型：科学学位(博) 科学学位(硕) 招生专业：口腔基础医学(博) 口腔基础医学(硕) 研究方向名称：干细胞介导的口腔颌面组织再生及分子调控机制 电子信箱：wang54384@163.com


社会任职
1. 北京口腔医学会口腔生物医学专业委员会主任委员
2. 《北京口腔医学》杂志编委
3. 《口腔生物医学》杂志编委
4. 中华口腔医学会口腔生物医学专业委员会副主任委员
5. 北京口腔医学会常务理事
6. 中国生物医学工程学会组织工程与再生医学分会委员
7. 中国医药质量管理协会临床试验及大数据质量管理分会委员
8. Int J Oral Sci，Editor board member
9. 中华口腔医学会口腔遗传病与罕见病专业委员会副主任委员
个人简历
1. 199109-199807:北京医科大学口腔医学院 7年制本硕连读生
2. 199809-200012:天津市口腔医院 住院医师
3. 200012-200108:天津市口腔医院 主治医师
4. 200109-200407:首都医科大学口腔医学院 博士研究生
5. 200408-200410:首都医科大学附属北京口腔医院 主治医师
6. 200410-200707:密西根大学 博士后
7. 200708-200910:加州大学洛杉矶分校 博士后
8. 200910-201012:首都医科大学附属北京口腔医院 主治医师
9. 201012-:首都医科大学附属北京口腔医院 研究员
10. 201208-:首都医科大学附属北京口腔医院 科副主任
11. 201301-:首都医科大学附属北京口腔医院 教授
12. 201312-:首都医科大学附属北京口腔医院 硕士研究生导师
13. 201512-:首都医科大学附属北京口腔医院 博士研究生导师
重要学术论文
1. Li G, Han N, Yang H, Wang L, Lin X, Diao S, Du J, Dong R, Wang S*, Fan Z*..Homeobox C10 inhibites the osteogenic differentiation potential of mesenchymal stem cells. Connect Tissue Res. 2018,59(3):201-211.SCI
2. Li W, Lin X, Yang H, Cao Y, Zhang C*, Fan Z*..Depletion of HOXA5 inhibits the osteogenic differentiation and the proliferation potential of the stem cells from apical papilla. Cell Boil Int. 2018,42(1):45-52.SCI
3. Cao Y, Yang H, Jin L, Du J, Fan Z*.Genome-wide DNA methylation analysis during osteogenic differentiation of human bone marrow mesenchymal stem cells. Stem Cell Int. 2018,2018:**.SCI
4. Cao Y#, Wang L#, Yang H, Lin X, Li G, Han N, Du J, Fan Z*.Epiregulin promotes the migration and chemotaxis ability of adipose-derived mesenchymal stem cells via mitogen-activated protein kinase signaling pathways. J Cell Biochem. 2018,119(10):8450-8459.SCI
5. Zhang W#, Dong R#, Diao S, Du J, Fan Z*, Wang F*..Differential long noncoding RNAs/mRNA expression profiling and functional network analysis during osteogenic differentiation of human bone marrow mesenchymal stem cells. Stem Cell Res Ther. 2017,8(1):30.SCI
6. Guo L, Jin L, Du J, Zhang C, Fan Z*, Wang S*. Depletion of SHANK2 inhibited the osteo/dentinogenic differentiation potentials of stem cells from apical papilla. Histol Histopathol. 2017,32(5):471-479.SCI
7. Yi Q#, Liu OS#, Yan F, Lin X, Diao S, Wang SL, Lu YQ*, Fan ZP*.Analysis of senescence-related differentiation potential and gene expression profiles in human dental pulp stem cells. Cells Tissues Organs. 2017,203(1):1-11.SCI
8. Lin X, Dong R, Diao S, Yu G, Wang L, Li J*, Fan Z*..SFRP2 enhanced the adipogenic and neoronal differentiation potentials of stem cells from apical papilla. Cell Biol Int. 2017,41(5): :534-543.SCI
9. Han N#, Zhang F#, Li G, Zhang X, Lin X, Yang H, Wang L, Cao Y, Du J, Fan Z*..Local application of IGFBP5 protein enhanced periodontal tissue regeneration via increasing the migration, cell proliferation and osteo/dentinogenic differentiation of mesenchymal stem cells in inflammatory niche. Stem Cell Res Ther. 2017,8(1):210.SCI
10. Yu GX#, Wang JS#, Lin X, Diao S, Cao Y, Dong R, Wang LP, Yang DM, Wang SL*, Fan ZP*.Demethylation of SFRP2 by Histone Demethylase KDM2A Regulated the Osteo-/dentinogenic Differentiation of Stem Cells from Apical Papilla. Cell Proliferat. 2016,49(3):330-340.SCI
11. Wang Y#, Jia Z#, Diao S, Lin X, Lian X, Wang L, Wang J, Liu D*, Dong R*, Fan Z*.IGFBP5 enhanced osteogenic differentiation potentials of mesenchymal stem cells via JNK and MEK/Erk signaling pathways. Cell Proliferat. 2016,49(5):618-627.SCI
12. Yi Q#, Cao Y#, Liu OS, Lu YQ, Wang JS, Wang SL, Fan ZP*.Spatial and temporal expression of histone demethylase Kdm2a during murine tooth development. Biotech Histochem. 2016,91(2):137-144.SCI
13. Diao S, Yang DM, Dong R, Wang LP, Wang JS, Du J, Wang SL, Fan Z*.Enriched trimethylation of lysine 4 of histone H3 of WDR63 enhanced osteogenic differentiation potentials of stem cells from apical papilla. J Endod. 2015,41(2):205-211.SCI
14. Liu D#, Wang Y#, Jia Z, Wang L, Wang J, Yang D, Song J, Wang S, Fan Z*.Demethylation of IGFBP5 by Histone Demethylase KDM6B Promotes Mesenchymal Stem Cell Mediated Periodontal Tissue Regeneration by Enhancing Osteogenic Differentiation and AntiInflammation Potentials. Stem Cells. 2015,33(8):2523-2536.SCI
15. Wang JJ, Dong R, Wang LP, Wang JS, Du J, Wang SL, Shan ZC*, Fan ZP*.Histone demethylase KDM2B inhibited the chondrogenic differentiation potentials of stem cells from apical papilla. Int J Clin Exp Med. 2015,8(2):2165-2173.SCI
16. Li J, Yan M, Wang Z, Jing S, Li Y, Liu G, Yu J*, Fan Z*.Effects of canonical NF-κB signaling pathway on the proliferation and odonto/osteogenic differentiation of human stem cells from apical papilla. Biomed Res Int. 2014,2014:319651.SCI
17. Yu S, Diao S, Wang J, Ding G, Yang D*, Fan Z*.Comparative analysis of proliferation and differentiation potentials of stem cells from inflamed pulp of deciduous teeth and stem cells from exfoliated deciduous teeth. Biomed Res Int. 2014,2014:930907.SCI
18. Dong R, Du J, Wang L, Wang J, Ding G, Wang S, Fan Z*.Comparison of long noncoding RNA and mRNA expression profiles in mesenchymal stem cells derived from human periodontal ligament and bone marrow. Biomed Res Int. 2014,2014:317853.SCI
19. Wang X, Qi S, Wang J, Xia D, Qin L, Zheng Z, Wang L, Zhang C, Jin L, Ding G, Wang S*, Fan Z*.Spatial and temporal expression of cKit in the development of the murine submandibular gland. J Mol Histol. 2014,45(4):381-389.SCI
20. Du J, Shan Z, Ma P, Wang S, Fan Z*.Allogeneic Bone Marrow Mesenchymal Stem Cells Transplantation for Periodontal Regeneration. J Dent Res. 2014,93(2）:183-188.SCI
21. Du J, Ma Y, Ma P, Wang S*, Fan Z*..Demethylation of Epiregulin Gene by Histone Demethylase FBXL11 and BCL6 Corepressor Inhibits Osteo/dentinogenic Differentiation. Stem Cells. 2013,31(1):126-136.SCI
22. Gao R, Dong R, Du J, Ma P, Wang S, Fan Z*.Depletion of histone demethylase KDM2A inhibited cell proliferation of stem cells from apical papilla by derepressed p15INK4B and p27Kip1. Mol Cell Biochem. 2013,379(1-2):115-122.SCI
23. Yu S#, Long J#, Yu J, Du J, Ma P, Ma Y, Yang D*, Fan Z*.Analysis of differentiation potentials and gene expression profiles of mesenchymal stem cells derived from periodontal ligament and Wharton’s jelly of the umbilical cord. Cells Tissues Organs. 2013,197(3):209-223.SCI
24. Dong R#, Yao R#, Du J, Wang S, Fan Z*.Depletion of histone demethylase KDM2A enhanced the adipogenic and chondrogenic differentiation potentials of stem cells from apical papilla. Exp Cell Res. 2013,319(18):2874-2882.SCI
25. Jiang Q#, Du J#, Yin X, Shan Z, Ma Y, Ma P, Du J*, Fan Z*.Shh signaling, negatively regulated by BMP signaling, inhibits the osteo/dentinogenic differentiation potentials of mesenchymal stem cells from apical papilla. Mol Cell Biochem. 2013,383(1-2):85-93.SCI
26. Cao Y, Xia DS, Qi SR, Du J, Ma P, Wang SL*, Fan ZP*.Epiregulin can promote proliferation of stem cells from dental apical papilla via MEK/Erk and JNK signalling pathways. Cell Prolif. 2013,46(4):447-456.SCI
27. Wang Y, Yan M, Yu Y, Wu J, Yu J*, Fan Z*.Estrogen deficiency inhibits the odonto/osteogenic differentiation of dental pulp stem cells via activating NFκB pathway. Cell Tissue Res. 2013,352(3):551-559.SCI
28. Ye L#, Fan Z#, Yu B#, Chang J, Al Hezaimi K, Zhou X, Park NH, Wang CY.Histone Demethylases KDM4B and KDM6B Promote Osteogenic Differentiation of Human MSCs. Cell Stem Cell. 2012,11(1):50-61.SCI
29. Fan Z, Du J, Liu H, Zhang H, Dlugosz AA, Wang CY, Fan M, Shen Y, Wang SL.A susceptibility locus on 1p32-1p34 for congenital macrostomia in a Chinese family and identification of a novel PTCH2 mutation. Am J Med Genet A. 2009,149A(3):521-524.SCI
30. Fan Z, Yamaza T, Lee JS, Yu J, Wang SL, Fan G, Shi S, Wang CY.BCOR regulates mesenchymal stem cell function by epigenetic mechanisms. Nat Cell Biol. 2009,11(8):1002-1009.SCI
31. Fan Z#, Li J#, Du J, Zhang H, Shen Y, Wang CY, Wang SL.A missense mutation in PTCH2 underlies dominantly inherited NBCCS in a Chinese family. J Med Genet. 2008,45(5):303-308.SCI
主编或副主编的著作/译著
重要奖项