姓名：杨晓葵 性别：女 职称：主任医师、教授 招生院所：附属妇产医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：妇产科学(博) 妇产科学(硕) 研究方向名称：生殖内分泌与辅助生殖技术 电子信箱：xiaokuiyang2012@163.com


社会任职
1. 中国优生科学协会 理事
2. 中国医疗保健国际交流促进会妇儿医疗保健专业委员会 常务委员
3. 北京医学会妇产科分会委员
4. 中国妇幼保健协会生育保健专业委员会委员
5. 中国妇幼保健协会辅助生殖技术监测与评估专业委员会委员
6. 《Obstetrics & Gynecology》中文版编委
7. 《中国计划生育和妇产科》 编委
8. 中国医疗保健国际交流促进会生殖感染与微生态专业委员会 常务委员
个人简历
1. 198709-199206:武汉大学医学部（湖北医科大学） 本科
2. 199207-199408:武汉大学人民医院妇产科 医师
3. 199409-199706:武汉大学医学部（湖北医科大学） 硕士
4. 199909-200206:华中科技大学同济医学院 博士
5. 200302-200502:加拿大渥太华大学 博士后/访问
6. 200810-200812:香港大学李嘉诚医学院玛丽医院 学习
7. 201308-:首都医科大学附属北京妇产医院 主任医师
8. 201401-:首都医科大学附属北京妇产医院 教授
重要学术论文
1. Zhao Feiyan, Lan Yonglian, Chen Tong, Xin Zhimin, Liang Yu, Li Ying, Wang Shuyu, Zhang Jun *, Yang Xiaokui *.Live birth rate comparison of three controlled ovarian stimulation protocols for in vitro fertilization-embryo transfer in patients with diminished ovarian reserve after endometrioma cystectomy: a retrospective study. J Ovarian Res. 2020,13(1):23.SCI
2. Hong Liming#, Yan Long#, Xin Zhimin, Hao Jie, Liu Wenjing, Wang Shuyu, Liao Shujie, Wang Hongmei*, Yang Xiaokui*.Protective effects of human umbilical cord mesenchymal stem cell-derived conditioned medium on ovarian damage. J Mol Cell Biol. 2019,Nov 19:mjz105.SCI
3. Chang Liu, Hsun-Ming Chang, Yuyin Yi, Ying Fang, Feiyan Zhao, Peter C.K. Leung∗, Xiaokui Yang∗.ALK4-SMAD2/3-SMAD4 signaling mediates the activin A-induced suppression of PTX3 in human granulosa-lutein cells. Mol Cell Endocrinol. 2019,493(8):110485.SCI
4. Yu Liang, Xiaokui Yang, Yonglian Lan, Lingling Lei, Ying Li*, Shuyu Wang*.Effect of Endometrioma cystectomy on Cytokines of follicular fluid and IVF outcomes. J Ovarian Res. 2019,12(1):98.SCI
5. Hong L#, Peng S#, Li Y#, Fang Y, Wang Q, Klausen C, Yin C, Wang S, Leung PCK*, Yang Xiaokui*.MiR-106a increases granulosa cell viability and is down-regulated in women with diminished ovarian reserve. J Clin Endocrinol Metab. 2018,103(6):2157-2166..SCI
6. 陈子江，田秦杰，乔杰，刘嘉茵，杨冬梓，黄荷凤，梁晓燕，秦莹莹，伍琼芳，杨晓葵，肖红梅，陈士岭，姚元庆，徐丛剑，曹云霞，张以文，庄广伦，陈贵安，林金芳，李尚为，朱桂金，章晓梅，华克勤，阮祥燕，吴洁，郁琦，孙赟.早发性卵巢功能不全的临床诊疗中国专家共识. 中华妇产科杂志 . 2017,52(9)::577-81..核心期刊
7. Qiaofei Hu#, Liming Hong#, Mingyue Nie, Qin Wang, Ying Fang, Yinmei Dai, Yanhong Zhai, Shuyu Wang, Chenghong Yin*, Xiaokui Yang*.The effect of dehydroepiandrosterone supplementation on ovarian response is associated with androgen receptor in diminished ovarian reserve women. Journal of Ovarian Research. 2017,10(1):32.SCI
8. Fang Y, Chang HM, Cheng JC, Klausen C, Leung PC*, Yang Xiaokui*.Transforming growth factor-β1 increases lysyl oxidase expression by downregulating MIR29A in human granulosa lutein cells. Reproduction. 2016,152(3):205-13.SCI
9. Chang HM, Fang Y, Liu PP, Cheng JC, Yang Xiaokui, Leung PC. .Connective tissue growth factor mediates growth differentiation factor 8-induced increase of lysyl oxidase activity in human granulosa-lutein cells. Mol Cell Endocrinol. 2016,434(10):186-98.SCI
10. Lei JH#, Yang Xiaokui#, Peng S#, Li Y, Underhill C, Zhu C, Lin Hai-Yan**, Wang H**, Hammond GL **.Impact of corticosteroid-binding globulin deficiency on pregnancy and neonatal sex. Journal of Clinical Endocrinology & Metabolism. 2015,Feb 19:jc**(共同第一).SCI
11. Li Y, Nie M, Liu Y, Zhang W, Yang Xiaokui*.The dynamic changes of Anti-Mullerian hormone and inhibin B during controlled ovarian hyperstimulation in decreased ovarian reserve women and the effect on clinical outcome. Gynecological Endocrinology. 2015,Jan 14:1-4.SCI
12. Li Y #, Fang Y #, Liu Y and Yang Xiaokui* .MicroRNAs in ovarian function and disorders. Journal of Ovarian Research. 2015,8:51.SCI
13. Nie M#, Yu S #, Peng S, Fang Y, Wang H*, Yang Xiaokui*.miR-23a and miR-27a promote human granulosa cell apoptosis by targeting SMAD5. Biology of Reproduction. 2015,93(4):98.SCI
14. Xiaokui Yang, Ying Li, Changdong Li, Weiyuan Zhang*.Current overview of pregnancy complications and live-birth outcome of assisted reproductive technology in mainland China. Fertil & Steril. 2014,101:385-391 .SCI
15. Xiaokui Yang, Qingxin Wang, Zhiying Gao, Zhi Zhou, Sha Peng, Wen-Lin Chang, Hai-Yan Lin, Weiyuan Zhang*, Hongmei Wang*.Proprotein Convertase Furin Regulates Apoptosis and Proliferation of Granulosa Cells in the Rat Ovary. PlosOne. 2013,8（2）:e50479.SCI
16. Xiaokui Yang, Jiandong Wang, Ying Zhou, Yamei Wang, Shuyu Wang*, Weiyuan Zhang*.Hsp70 promotes chemoresistance by blocking Bax mitochondrial translocation in ovarian cancer cells. Cancer Letters. 2012,321（2）:137-43.SCI
17. Xiaokui Yang, Ying Zhou, Sha Peng, Liang Wu, Hai-Yan Lin, Shuyu Wang*, and Hongmei Wang*.Differentially expressed plasma microRNAs in premature ovarian failure patients and the potential regulatory function of mir-23a in granulosa cell apoptosis. Reproduction . 2012,144（2）:235-244.SCI
18. 杨晓葵,段华.输卵管手术与卵巢储备功能损伤. 实用妇产科杂志. 2012,28（6）:420-421.核心期刊
19. Yang Xiaokui, Fraser M, Abedini MR, Bai T, Tsang BK*.Regulation of AIF-Mediated, Cisplatin-Induced Apoptosis by Akt. Br J Cancer. 2008,98(4):803-808.SCI
20. Yang Xiaokui, Fraser M, Moll U, Basak A and Tsang BK*.Akt-mediated Cisplatin resistance in Ovarian Cancer: Modulation of p53 Action on Caspase-dependent Mitochondrial Death Pathway. . Cancer Research. 2006,66:3126-3136.SCI
21. Xiaokui Yang, Hui Xing, Gao Qinglei, Ma Ding*..Regulation of HtrA2/Omi by X-linked Inhibitor of Apoptosis Protein in Cisplatin-resistance in Human Ovarian Cancer Cells. Gynecologic Oncology. 2005,97:413-421.SCI
22. Xiaokui Yang, Fang Zheng, Hui Xing, Ma Ding*..Resistance to chemotherapy-induced apoptosis via decreased caspase-3 activity and overexpression of antiapoptotic proteins in ovarian cancer.. Journal of Cancer Research and Clinical Oncology . 2004,130:423-428.SCI
23. 杨晓葵，郑芳，邢辉，马丁*.凋亡相关蛋白和半胱天冬氨酸蛋白酶-3在卵巢癌顺铂耐药的作用. 中华妇产科杂志. 2003,38（3）:158-161.核心期刊
24. 杨晓葵，郑芳，邢辉，马丁*.应用mdr-1核酶逆转人卵巢癌的多药耐药. 中华肿瘤杂志. 2003,25(5) :425-428.核心期刊
25. 杨晓葵，郑芳，邢辉，马丁*.细胞色素c 介导的Caspase-3活性改变与人卵巢癌顺铂耐药的关系. 中华肿瘤杂志. 2002,24（6）:544-547 .核心期刊
主编或副主编的著作/译著
重要奖项
1. 北京市医管中心“登峰”人才计划 201912
2. 第二届妇幼健康科学技术奖自然科学奖二等奖 201711
3. 北京市卫生系统高层次卫生人才“学科骨干” 2011
4. 北京市卫生局“十百千”百级人才 200810
5. 香港大学李嘉诚医学院“郑裕彤奖学金” 200810
6. 北京市优秀人才 200612