职 称：教授/博士生导师
性 别：男
出生年月：1965年9月
专 业：物理化学
办公电话：
Email：mazhanfang@126.com
【个人情况综述】
马占芳，教授（博导）、系主任
长期从事胶体与界面化学领域的研究工作，在纳米材料的制备和组装、新型纳米生物探针研制、纳米生物识别与检测、电化学生物传感器等方面做了系统的研究工作。在包括Nature Communications, J. Am. Chem. Soc., Angew. Chem. Int. Ed., Adv. Funct. Mater., Chem. Mater., Biosens. Bioelectron.等在内的国际主流学术期刊上发表研究论文150余篇，这些文章被SCI论文正面引用4000余次。2005年获得国家自然科学奖二等奖（第四位）。“癌症早期诊断纳米新技术”北京市知识创新团队负责人。
【代表性科研成果（论文、专利）】
1. Y. X. Liu, Z. Wei, J. Zhou*, Z. F. Ma*. Simultaneous multi-signal quantification of a single bio-indicator improves the precision of serodiagnosis. Nature Communications 2019, 10, 5361.
2. C. Zhang, Z. F. Ma*. PtCu nanoprobe-initiated cascade reaction modulated iodide-responsive sensing interface for improved electrochemical immunosensor of neuron-specific enolase. Biosens. Bioelectron. 2019, 143, 111612.
3. S. Yin, Z. F. Ma*. Self-sacri?cial label assisted electroactivity conversion of sensing interface for ultrasensitive electrochemical immunosensor. Biosens. Bioelectron. 2019, 140, 111355.
4. C. S. Chu, S. Rao, Z. F. Ma*, H. L. Han*. Copper and cobalt nanoparticles doped nitrogen-containing carbon frameworks derived from CuO-encapsulated ZIF-67 as high-efficiency catalyst for hydrogenation of 4-nitrophenol. Applied Catalysis B 2019, 256, 117792.
5. L. H. Zhao, S. Yin, Z. F. Ma*. Ca²⁺-triggered pH-response sodium alginate hydrogel precipitation for amplified sandwich-type impedimetric im-munosensor of tumor marker. ACS Sensors 2019, 4, 450-455.
6. Y. Zheng, Z. F. Ma*. Multifunctionalized ZIFs nanoprobe-initiated tandem reaction for signal amplified electrochemical immunoassay of carbohydrate antigen 24-2. Biosens. Bioelectron. 2019, 129, 42-49.
7. J. C. Zhao, D. Shu, Z. F. Ma*. Target-inspired Zn²⁺-dependent DNAzyme for ultrasensitive impedimetric aptasensor based on polyacrylic acid nanogel as amplifier. Biosens. Bioelectron. 2019, 127, 161-166.
8. Y. Zheng, L. H. Zhao, Z. F. Ma*. pH responsive label-assisted click chemistry triggered sensitivity amplification for ultrasensitive electrochemical detection of carbohydrate antigen 24-2. Biosens. Bioelectron. 2018, 115, 30-36.
9. J. C. Zhao, Z. F. Ma*. Ultrasensitive detection of prostate specific antigen by electrochemical aptasensor using enzyme-free recycling amplification via target-induced catalytic hairpin assembly. Biosens. Bioelectron. 2018, 102, 316-320.
10. L. H. Zhao, H. L. Han, Z. F. Ma*. Improved screen-printed carbon electrode for multiplexed label-free amperometric immuniosensor: Addressing its conductivity and reproducibility challenges. Biosens. Bioelectron. 2018, 101, 304-310.
11. Y. Zheng, Z. F. Ma*. Dual-reaction triggered sensitivity amplification for ultrasensitive peptide-cleavage based electrochemical detection of matrix metalloproteinase-7. Biosens. Bioelectron. 2018, 108, 46-52.
12. Z. X. Tang, Y. Y. Fu, Z. F. Ma*. Bovine serum albumin as an effective sensitivity enhancer for peptide-based amperometric biosensor for ultrasensitive detection of prostate specific antigen. Biosens. Bioelectron. 2017, 94, 394-399.
13. Z. X. Tang, L. Y. Wang, Z. F. Ma*. Triple sensitivity amplification for ultrasensitive electrochemical detection of prostate specific antigen. Biosens. Bioelectron. 2017, 92, 577-582.
14. Z. X. Tang, Y. Y. Fu, Z. F. Ma*. Multiple signal amplification strategy for ultrasensitive label-free electrochemical immunoassay for carbohydrate antigen 24-2 based on redox hydrogel. Biosens. Bioelectron. 2017, 91, 299-305.
15. Z. X. Tang, Z. F. Ma*. Multiple functional strategies for amplifying sensitivity of amperometric immunoassay for tumor markers: A review. Biosens. Bioelectron. 2017, 98, 100-112.
16. J. Shan, Z. F. Ma*. A review on amperometric immunoassays for tumor markers based on the use of hybrid materials consisting of conducting polymers and noble metal nanomaterial. Microchim. Acta 2017, 184, 969-979.
17. D. Shu, F. Feng, H. L. Han, Z. F. Ma*. Prominent adsorption performance of amino-functionalized ultra-light graphene aerogel for methyl orange and amaranth. Chemical Engineering Journal 2017, 324, 1-9.
18. Q. F. Rong, F. Feng, Z. F. Ma*. Metal ions doped chitosan-poly(acrylic acid) nanospheres: synthesis and their application in simultaneously electrochemical detection of four markers of pancreatic cancer. Biosens. Bioelectron. 2016, 75, 148-154.
19. Z. F. Ma*, N. Liu. Design of immunoprobes for electrochemical multiplexed tumor marker detection. Expert Review of Molecular Diagnostics 2015, 15, 1075-1083. (Invited Review)
20. L. Y. Wang, N. Liu, Z. F. Ma*. Novel gold-decorated polyaniline derivatives as redox-active species for simultaneous detection of three biomarkers of lung cancer. J. Mater. Chem. B 2015, 3, 2867-2872.
21. Z. F. Wang, N. Liu, F. Feng, Z. F. Ma*. Synthesis of cadmium, lead and copper alginate nanobeads as immunosensing probes for the detection of AFP, CEA and PSA. Biosens. Bioelectron. 2015, 70, 98-105.
22. Z. M. Liu, Q. F. Rong, Z. F. Ma*, H. L. Han*. One-step synthesis of redox-active polymer/Au nanocomposites for electrochemical immunoassay of multiplexed tumor markers. Biosens. Bioelectron. 2015, 65, 307-313.
23. Z. F. Wang, X. Chen, Z. F. Ma*. Chitosan coated cupper and cadmium hexacyanocobaltate nanocubics as immunosensing probes for the construction of multiple analytes platform. Biosens. Bioelectron. 2014, 61, 562-568.
24. N. Liu, Z. M. Liu, H. L. Han, Z. F. Ma*. Graphene oxide reduced directly by redox probes for multiplexed detection of tumor markers. J. Mater. Chem. B 2014, 2, 3292 -3298.
25. X. Chen, Z. F. Ma*. Multiplexed electrochemical immunoassay of biomarkers using chitosan nanocomposites. Biosens. Bioelectron. 2014, 55, 343-349.
26. Z. F. Wang, N. Liu, Z. F. Ma*. Platinum porous nanoparticles hybrid with metal ions as probes for simultaneous detection of multiplex cancer biomarkers. Biosens. Bioelectron. 2014, 53, 324-329.
27. X. L. Jia, Z. M. Liu, N. Liu, Z. F. Ma*. A label-free immunosensor based on graphene nanocomposites for simultaneous multiplexed electrochemical determination of tumor markers. Biosens. Bioelectron. 2014, 53, 160-166.
28. X. L. Jia, X. Chen, J. M. Han, J. Ma, Z. F. Ma*. Triple signal amplification using gold nanoparticles, bienzyme and platinum nanoparticles functionalized graphene as enhancers for simultaneous multiple electrochemical immunoassay. Biosens. Bioelectron. 2014, 53, 65-70.
29. N. Liu, Z. F. Ma*. Au-ionic liquid functionalized reduced graphene oxide immunosensing platform for simultaneous electrochemical detection of multiple analytes. Biosens. Bioelectron. 2014, 51, 184-190.
30. P. P. Bian, J. Zhou, Y. Y. Liu, Z. F. Ma*. One-step fabrication of intense red fluorescent gold nanoclusters and their application in cancer cell imaging. Nanoscale 2013, 5, 6161-6166.
31. X. Chen, X. L. Jia, J. Ma, Z. F. Ma*. Electrochemical immunosensor for simultaneous detection of multiplex cancer biomarkers based on graphene nanocomposites. Biosens. Bioelectron. 2013, 50, 356-361.
32. Y. X. Li, J. Ma, Z. F Ma*. Synthesis of gold nanostars with tunable morphology and their electrochemical application for hydrogen peroxide sensing. Electrochim. Acta 2013, 108, 435-440.
33. Q. Gao, J. M. Han, Z. F. Ma*. Polyamidoamine dendrimers-capped carbon dots/Au nanocrystal nanocomposites and its application for electrochemical immunosensor. Biosens. Bioelectron. 2013, 49, 323-328.
34. J. M. Han, J. Ma, Z. F. Ma*. One-step synthesis of poly(thionine)-Au nano-network and nanowires and its application for non-enzyme biosensing of hydrogen peroxide. Electrochem. Commun. 2013, 33, 47-50.
35. N. Liu, X. Chen, Z. F. Ma*. Ionic liquid functionalized graphene/Au nanocomposites and its application for electrochemical immunosensor. Biosens. Bioelectron. 2013, 48, 33-38.
36. J. M. Han, J. Ma, Z. F. Ma*. One-step synthesis of graphene oxide–thionine–Au nanocomposites and its application for electrochemical immunosensing. Biosens. Bioelectron. 2013, 47, 243-247.
37. Z. M. Liu, Z. F. Ma*. Fabrication of an ultrasensitive electrochemical immunosensor for CEA by conducting long-chain polythiols. Biosens. Bioelectron. 2013, 46, 1-7.
38. X. B. Sun, Z. F. Ma*. Highly stable electrochemical immunosensor for carcinoembryonic antigen. Biosens. Bioelectron. 2012, 35, 470-474.
39. R. M. Wang, J. Di, J. Ma, Z. F. Ma*. Highly sensitive detection of cancer cells by electrochemical impedancespectroscopy. Electrochim. Acta 2012, 61, 179-184.
40. B. Liu, Z. F. Ma*, Synthesis of Ag2S-Ag nanoprisms and their use as oligonucleotide probes. Small 2011, 7, 1587-1592.
41. W. T. Shi, Z. F. Ma*, A novel label-free amperometric immunosensor for carcinoembryonic antigen based on redox membrane. Biosens. Bioelectron. 2011, 26, 3068-3071.
42. W. T. Shi, Z. F. Ma*. Amperometric glucose biosensor based on a triangular silver nanoprisms/chitosan composite film as immobilization matrix. Biosens. Bioelectron. 2010, 26, 1098-1103.
43. C. G. Wang, Y. Chen, T. T. Wang, Z. F. Ma*, Z. M. Su. Monodispersed gold nanorods embedded silica particles as novel Raman labels for biosensing. Adv. Funct. Mater. 2008, 18, 355-361.
44. C. G. Wang, Y. Chen, T. T. Wang, Z. F. Ma*, Z. M. Su, Biorecognition-driven self-assembly of gold nanorods: A rapid and sensitive approach toward antibody sensing. Chem. Mater. 2007, 19, 5809-5811.
45. C. G. Wang, Z. F. Ma*, T. T. Wang, Z. M. Su. Synthesis, assembly and biofunctionalization of silica-coated gold nanorods for colorimetric biosensing. Adv. Funct. Mater. 2006, 16, 1673-1678.
46. Z. F. Ma, S.-F. Sui. Naked-eye sensitive detection of Immunoglubulin G by enlargement of Au-nanoparticles immobilized in vitro. Angew. Chem. Int. Ed. 2002, 14, 2176-2179.
47. Z. F. Ma, J. R. Li, M. H. Liu, J. Cao, Z. Y. Zou, J. Tu, L. Jiang. Colorimetric detection of Escherichia coli by polydiacetylene vesicles functionalized with glycolipid. J. Am. Chem. Soc. 1998, 120, 12678-12679.
【指导的研究生获国家奖学金情况】
2019 年 楚常顺
2018年 郑云 张东生
2017年 王辉强
2016年 单姣
2015年 荣勤峰、邢立文
2014年 徐腾、王子凤
2013年 贾新乐、卞平平、刘娜
2012年 孙晓斌（第一届国奖）