教师简介

姓名：康友敏
性别：女
职称：副教授，硕士生导师
学历：博士
专业：分子免疫学
毕业院校：中国农业大学


学习与工作经历

2010.01-现在中国农业大学生物学院,副教授研究方向：分子免疫学
2007.07-2009.12中国农业大学生物学院,讲师
2006.03-2007.03美国伊利诺伊大学医学院,联合培养
2003.09-2007.06中国农业大学，博士
2000.09-2003.07河北师范大学，硕士


研究方向

记忆性T细胞及Treg细胞凋亡在自身免疫疾病发病中的作用机制；

前列腺素调控免疫细胞在孕晚期维持母胎耐受中的作用；

耐受免疫的方法预防和治疗自身免疫疾病的作用机理；

佐剂提高病毒性传染疾病灭活疫苗及DNA疫苗免疫效果的研究。

主讲课程

1.本科生课程：《免疫技术原理与应用》、《生物学B》、《生物学实验》、《病毒学》、
《动物生理学B实验》。
2.研究生课程:《分子免疫学专题》、《现代微生物研究技术》。


联系方式

电话：62734749
邮件：kym
通讯地址：中国农业大学生物学院生命科学研究中心3078





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发表文章
1.JingyaoZhang,WenjuanGao,XuYang,JingjingKang,QiruiGuo,YanxinHu,GuoliangXiaandYouminKang*.TolerogenicvaccinationsuppressedCD4memoryTcellsandinducedmemoryTregcellsforTypeIdiabetestreatment.PLoSONE,2013;8(7):e70056
2.WenjuanGao,YuanhanSun,ShiwenChen,JingyaoZhang,JingjingKang,YongqiangWang,HexiangWang,GuoliangXia,QinghongLiu*andYouminKang*.MushroomlectinenhancedimmunogenicityofHBVDNAvaccineinC57BL/6andHBsAg-transgenicmice.Vaccine,2013;31(18):2273-2280
3.YouminKang*,YuhanSun,JingyaoZhang,WenjuanGao,JingjingKang,YongqiangWang,BinWang,GuoliangXia.TregCellResistancetoApoptosisinDNAVaccinationforExperimentalAutoimmuneEncephalomyelitisTreatment.PLoSONE,2012;7(11):e49994
4.YouminKang*,GuoxingZheng,AoshuangChen,JunpengWang,YanxinHu,JinyaoLi,JingyaoZhang,WenjuanGao,HongyeFu,GuoliangXia,andBinWang.TolerogenicDNAvaccineforpreventionofautoimmuneovariandisease.ImmunologicalInvestigation,2012;41(3):249-260
5.YouminKang,JiaZhao,YueLiu,AoshuangChen,GuoxingZheng,YangYu,JianjieMi,QiangZouandBinWan.TolerogenicDNAvaccinationforpreventionofexperimentalautoimmuneencephalomyelitis.2009,JGeneMed;11:1064-1070
6.YouminKang,LipengXu,BinWang,AoshuangChenandGuoxingZheng.Immunosuppressivedrugsasadjuvantfortolerogenicimmunization.2008,Journalofimmunology,180(8):5172-5176
7.YouminKang,AoshuangChen,BinWang,andGuoxingZheng.ProteinTransferEnhancesCellularImmuneResponsestoDNAVaccinationAgainstSARS-CoV.2009,ViralImmunology,22:417-422
8.YouminKang,HualiJin,GuoxingZheng,XiaogangDu,ChongXiao,XiaoyingZhang,ShuangGeng,XiaolinLi,JunpengWang,AoshuangChenandBinWang.Co-inoculationofantigen-matchedDNAandproteinvaccinesinducesantigen-specificTcellsuppression.2007,BiochemicalandBiophysicalResearchCommunications,353:1034-1039
9.YouminKang,HualiJin,QifaXie,JiangmeiYin,YangYu,ChongXiao,XiaoyingZhangandBinWang.EffectofLevamisoleasanAdjuvantonInactivatedViralVaccine.Vaccine,2005,23:5543-5550
10.HualiJin,YouminKang(co-firstauthor),GuoxingZheng,QifaXie,ChongXiao,XinyuZhang,YangYu,KaichunZhu,GanZhao,FuchunZhang,AoshuangChenandBinWang.Inductionofactiveimmunesuppressionbyco-immunizationwithDNA-andprotein-basedvaccines.Virology,2005,20;337(1):183-191
11.ShuangGeng,YangYu,YouminKang,GeorgePavlakis,HualiJin,JinyaoLi,YanxinHu,WeibinHu,ShuangWangandBinWang.EfficientinductionofCD25-iTregbyco-immunizationrequiresstronglyantigenicepitopesforTcells.BMCImmunology2011,12:27
12.MaoG,WangJ,KangY,TaiP,WenJ,ZouQ,LiG,OuyangH,XiaG,WangB.ProgesteroneincreasessystemicandlocaluterineproportionsofCD4+CD25+Tregcellsduringmidtermpregnancyinmice.Endocrinology.2010,151(11):5477-88
13.QiangZou,YiweiZhong,HairuiSu,YouminKang,JinJin,QiangLiu,ShuangGeng,GanZhao,BinWang.EnhancementofhumoralandcellularresponsestoHBsAgDNAvaccinationby2immunizationwithpraziquantelthroughinhibitionTGF-beta/Smad2,3signaling.Vaccine2010;28(8):2032-2038
14.QiangZou,YiweiZhong,HairuiSu,YouminKang,JinJin,QiangLiu,ShuangGeng,GanZhao,BinWang.EnhancementofhumoralandcellularresponsestoHBsAgDNAvaccinationby2immunizationwithpraziquantelthroughinhibitionTGF-beta/Smad2,3signaling.Vaccine2010;28(8):2032-2038
15.ZhangWenjuan,JinHuali,HuYanxin,YuYang,LiXiaolin,DingZheng,KangYoumin,WangBin.Protectiveresponseagainsttype1diabetesinnonobesediabeticmiceaftercoimmunizationwithinsulinandDNAencodingproinsulin.HumGeneTher2010;21(2):171-178
16.GanZhao,HualiJin,BaoweiSu,XiaogangDu,YouminKang,XiaoWang,BinWang.PyNTTTTGToligonucleotide,aNovelEffectiveAdjuvantonFMDVDNAVaccine.ViralImmunology,Viralimmunology2009;22(2):131-138
17.WenjuanZhang,XiaogangDu,GangZhao,HualiJin,YouminKang,ChongXiao,MingyuLiuandBinWang.LevamisoleasanadjuvantforasubunitHBVvaccinethroughthepotentialup-regulationoftheMyD88dependentToll-likereceptors7/8pathway.Vaccine2009,27:4938-4946
18.HualiJin,YouminKang,LinZhao,SteveChu,TerryNg,ChongXiao,XiaogangDu,Xiaolin,SunandBinWang.PreventionofFleaAllergyDermatitisviaInductionofAntigenSpecificAdaptiveT_RcellsbyCo-InoculationofDNAplusProteinregimens.2008，JournalofImmunology,180(8):5360-5372
19.HualiJin,ChongXiao,ShuangGeng,YanxinHu,RuipingShe,YangYu,YouminKangandBinWang.ProtectionfromasthmaduetoantigenspecificTrcellsinducedbyco-vaccination.Eur.J.Immunol.2008.38:2452–2464Vaccine.2008,19;26(40):5111-5122
20.SuBaowei,WangJunpeng,WangXiaoJinHuali,ZhaoGan,DingZheng,KangYoumin,WangB.TheeffectsofIL-6andTNF-alphaasmolecularadjuvantsonimmuneresponsestoFMDVandmaturationofdendriticcellsbyDNAvaccination.Vaccine.2008,19;26(40):5111-5122
21.PingTai,JunpengWang,HualiJin,XiaomingSong,JunYan,YouminKang,LinZhao,XiaojinAn,XiaogangDu,XiufenChen,GuoliangXiaandBinWang.EstrogenisapotentialmediatortoconvertactivatedCD4+CD25-TcellsintoCD4+CD25+regulatoryTcells.J.Cell.Physol.2008,214:456-464
22.Zhao,XiaogangDu,YangYu,YouminKangandBinWang.InductionofImmatureDendriticCellApoptosisbyFootandMouthDiseaseVirusIsanIntegrinReceptorMediatedEventbeforeViralInfection.J.Cell.Biochem.2007,102:980-991
23.HualiJin,XiaoWang,ChongXiao,YangYu,YouminKang,XiaogangDu,XuefengWei,andBinWang.EnhancementofFMDV-specifichumoralandcellularimmuneresponsesbyvaccinationwithDNAexpressingviral-like-particle.ViralImmunol.2007,20,429-440
24.AoshuangChen,ShanrongLiu,DavidPark,YouminKang,andGuoxingZheng.DepletingintratumoralCD4⁺CD25⁺regulatoryTcellsviaFasLproteintransferenhancesthetherapeuticefficacyofadoptiveTcelltransfer.2007,CancerResearch,67(3):1291-1298
25.XiaogangDu,GuoxingZheng,HualiJin,YouminKang,JunpengWang,ChongXiao,ShuoZhang,MingyuLiu,LinZhao,AoshuangChenandBinWang.EffectoftheCo-stimulatorymolecules,4-1BBL,OX40LandCD70,asadjuvantsonthecellularandmemoryresponsesonHBsAgDNAvaccination.J.GeneMedicine,2007,9:136–146
26.XiaoChong,JinHuali,HuYnxin,KangYoumin,WangJ,DuXiaogang,YangYu,SheRuping,WangBin.Enhancedprotectiveefficacyandreducedviralloadoffoot-and-mouthdiseaseDNAvaccinewithco-stimulatorymoleculesasthemolecularadjuvants.AntiviralRes.2007,76:11-22
27.HualiJin,YouminKang,QifaXie,ChongXiao,JunwuMa,QinggeXie，ChengHe,XinyuZhang,MinyongChen,ZhanshengYang,ZhiSun，FuchunZhang,andBinWang.DNAprimefollowedbyproteinboostenhancesneutralizationandTh1typeimmunityagainstFMDV.Virol.Immun.2005,18:539-548
28.JiangmeiYin,HualiJin,YouminKang,ChongXiao,LinZhao,XiaolinLi,ZhengDing,FuYang,QinghongZhu,BinWang,EfficacyofModifiedLevamisoleAdjuvantonInactivatedVirusVaccine.ViralImmunology,2006,19(3):525-535
29.H.L.Jin,ChongXiao,ZeChen,YouminKang,YijieMa,KaichunZhu,QifaXie,YixianTu,YangYu,BinWang.InductionofTh1typeresponsebyDNAvaccinationswithN,M,andEgenesagainstSARS-CoVinmice.BBRC.2005,328:979-986



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获奖情况

2009年参加《中国免疫学杂志》第十二届学术论文研讨会，论文被评为优秀论文；
2010年获中国农业大学2010届本科生“百篇优秀毕业论文（设计）”优秀指导教师奖；
2011年中央高校基本科研业务费-青年教师科研项目-被评为优秀课题；
2011年中国农业大学优秀班主任；
2012年中国农业大学班主任标兵。




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承担项目及课题

1.正在主持国家自然基金面上项目1项（31270956）、执行农业生物技术国家重点实验室重大课题1项（2011SKLAB01-2）、国家大学生创新计划2项。
2.已完成：国家自然基金面上项目1项（31070805）、教育部博士点新教师基金1项（200800191026）、中国农业大学基础科研业务费专项基金—青年教师项目1项（2010JS070）、农业生物技术国家重点实验室开放课题1项（2009SKLAB08-2）、中国农业大学科研启动金1项（2007049）、农业微生物资源及其应用农业部重点实验室青年课题1项、生物学理科基地项目1项（J0730639）和大学生创新计划3项（20070211/091001913/201210019039）、北京市大学生科学研究与创业行动计划2项(2011BKS-12/2012bj011)、生物学院本科生创新计划3项。




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专利情况

王宾，康友敏，2009，免疫抑制剂作为DNA疫苗佐剂预防自身免疫疾病，专利编号200910083049.7，授权公告日：2013年4月10日

WangBin，JinHuali,KangYoumin,ZhangWenjuan,YuYang,LiJinyao.2008,VaccinePreventingand/orTreatingAutoimmuneDisease，WO/2008/116380，PCT/CN2008/000540

WangBin，JinHuali,KangYoumin,CHU,Hsien-Jue，NG,Kaleung.ALLERGYINHIBITORCOMPOSITIONSANDKITSANDMETHODSOFUSINGTHESAME.WO/2007/076084,PCT/US2006/049161

WangBin，YuQingling,JinHuali,KangYouminTCELLIMMUNERESPONSEINHIBITOR.WO/2005/079833,PCT/CN2005/0001

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