（2020-01-22 网页更新）

1、个人简历
王刚，男，博士，副研究员，硕士生导师，猪免疫抑制病研究创新团队。主要研究方向为猪免疫抑制性疾病（PRRSV、PCV2/3、PRV）临床免疫学研究、动物疫苗及动物生物制品研制。近年来，先后主持国家自然科学基金项目、黑龙江省自然科学基金等项目。在Trends Microbiol、J Gen Virol、Transbound Emerg Dis、Dev Comp Immunol和Vet Microbiol等专业杂志发表科技论文50多篇，SCI论文累计影响因子≥100，被国内外同行引证300余次。
2、联系方式
（1）研究方向：兽医微生物及其流行病学
（2）电话：
（3）邮箱：wanggang@caas.cn
（4）通讯地址：黑龙江省哈尔滨市香坊区哈平路678号
3、教育经历
2002.09–2006.06山东农业大学，动物医学，本科
2006.09–2011.06山东农业大学，预防兽医学，博士
4、工作经历
2011.07-2016.12中国农业科学院哈尔滨兽医研究所，助理研究员
2017.01-至今 中国农业科学院哈尔滨兽医研究所，副研究员
2018/03-2018/03美国Iowa State University，访问****
5、承担项目
（1）高致病性PRRSV（HuN4 株）对仔猪中枢免疫器官的感染及损伤机制的研究、国家自然科学基金青年基金项目、**、2013/01-2015/12、主持；
（2）高致病性PRRSV驱动胸腺细胞程序性死亡的分子机制、黑龙江省自然科学基金（面上）项目、C**、2016/ 07-2019/07、主持；
（3）现代化规模猪场检测体系建设、横向课题（共2项）、2018/01-2022/12、主持；
（4）新型动物专用生物药物的创制及产业化关键技术研究、国家科技支撑计划、2015/04-2019/12、项目骨干；
6、获得学术奖励
王刚(11/19)，猪繁殖与呼吸综合征防控创新团队，中华人民共和国农业部，中华农业科技奖，优秀创新团队奖（等同于科研成果一等奖），2015
（蔡雪辉，童光志，刘永刚，田志军，周艳君，王洪峰，柴文君，安同庆，彭金美，涂亚斌，王刚，翁长江，王靖飞，何希君，姜成刚，王淑杰，孙明霞，李江南，黄丽）
7、授权发明专利
涂亚斌，蔡雪辉，王刚，刘永刚. 一种胸腺素α1-猪干扰素α融合蛋白基因及其重组蛋白的制备方法，2019.09.03，中国，ZL8.X
8、代表论文与著作
(1) Wang G#*, Yu Y#, Cai XH, Zhou E-M, Zimmerman JJ*. (2019) Effects of PRRSV infection on the porcine thymus. Trends Microbiol DOI: 10.1016/j.tim.2019.10.009. （Cell子刊，IF=11.974）
(2)Wang SJ, Lyc C, Duan GX, Meng FD, Yang YB, Yu Y, He XJ, Wang ZZ, Gottschalk M, Li GW, Cai XH*, Wang G*.Streptococcus suis Serotype 2 Infection Causes Host Immunomodulation Through Induction of Thymic Atrophy. Infect Immun. 2020. Accept. (*通讯作者，IF: 3.16)
(3)Yu Y, Zhang L, Chen Y, Li Y, Wang ZZ, Li G, Wang G*, Xin JQ*. GroEL protein (Heat shock protein 60) of Mycoplasma gallisepticum induces apoptosis in host cells by interacting with Annexin A2. Infect Immun. 2019, 87:9 (*通讯作者，IF: 3.16) (*通讯作者，IF: 3.16)
(4)Wang G*, Yu Y, He X, Wang M, Cai X, Zimmerman JJ*, Porcine reproductive and respiratory syndrome virus infection of bone marrow: Lesions and pathogenesis. Virus Res. 2019, 265: 20-29 (IF: 2.736)
(5) Wang HM, Liu YG, Tang YD, Liu TX, Zheng LL, Wang TY, Liu SG, Wang G*, Cai XH*. A natural recombinant PRRSV between HP-PRRSV JXA1-like and NADC30-like strains. Transbound Emerg Dis. 2018, 65, 1078-1086. (*通讯作者，IF: 3.554)
(6)Tong J, Yu Y, Zheng L, Zhang C, Tu Y, Liu Y, Wu J, Li H, Wang S, Jiang C, Zhou EM, Wang G*, Cai X*. Hypothalamus-pituitary-adrenal axis involves in anti-viral ability through regulation of immune response in piglets infected by highly pathogenic porcine reproductive and respiratory syndrome virus. BMC Vet Res. 2018, 14, 92. (*通讯作者，IF: 1.792)
(7) Tu YB#*, Wang G#, Wang YQ, Chen WY, Zhang L, Liu YG, Jiang CG, Wang SJ, Bu ZG, Cai XH*. Extracellular expression and antiviral activity of a bovine interferon-alpha through codon optimization in Pichia pastoris. Microbiol Res. 2016, 191: 12-18. (IF=3.037; #:共同第一作者)
(8)Wang G, Yu Y, Zhang C, Tu YB, Tong J, Liu YG, Chang YF, Jiang CG, Wang SJ, Zhou E-M*, Cai XH*. Immune responses to modified live virus vaccines developed from classical or highly pathogenic PRRSV following challenge with a highly pathogenic PRRSV strain. Dev Comp Immunol. 2016, 62: 1-7. doi: 10.1016/j.dci.2016.04.019. (IF=3.218)
(9)Dong JG#, Wang G#, Liu YG, Shi WD, Wu JN, Wen HQ, Wang SJ, Tian ZJ, Cai XH*. Quantitative estimation of the replication kinetics of genotype 2 PRRSV strains with different levels of virulence in vitro. J Virol Methods. 2016, 234: 87-9. (IF=1.508; #:共同第一作者)
(10)Wang G, Li L, Yu Y, Tu YB, Tong J, Zhang C, Liu YG, Li YM , Han ZF, Jiang CG, Wang SJ, Zhou E-M, He XJ*, Cai XH*. Highly pathogenic porcine reproductive and respiratory syndrome virus infection and induction of apoptosis in bone marrow cells of infected piglets. J Gen Virol. 2016, 97: 1356-1361. (IF=3.192)
(11)Wang G, Yu Y, Tu YB, Li YM, Tong J, Zhang C, Liu YG, Li AD, Jiang CG, Wang SJ, Tao Y, Cai XH*.Characterizing the thymic lesions in piglets infected with attenuated strains of highly pathogenic porcine reproductive and respiratory syndrome virus. Vet Immunol Immunopathol.2015, 15(3-4): 258-61. (IF=1.664)
(12)Wang G, Yu Y, Tu Y, Tong J, Liu Y, Zhang C, Chang Y, Wang S, Jiang C, Zhou EM*, Cai X*. Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Infection Induced Apoptosis and Autophagy in Thymi of Infected Piglets. PLoS One. 2015, 10, e**. (IF: 3.057)
(13)Li Y#, Wang G#, Liu Y, Tu Y, He Y, Wang Z, Han Z, Li L, Li A, Tao Y, Cai X*. Identification of apoptotic cells in the thymus of piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virus. Virus Res. 2014, 189:29-33. (IF=2.324; #:共同第一作者)
(14)Wang G, He YL, Tu YB, Liu YG, Zhou EM, Han ZF, Jiang CG, Wang SJ, Shi WD, Cai XH*. Comparative analysis of apoptotic changes in peripheral immune organs and lungs following experimental infection of piglets with highly pathogenic and classical porcine reproductive and respiratory syndrome virus. Virol J. 2014, 11:2. (IF=2.181)
(15)Wang G, Song TF, Yu Y, Liu YG, Shi WD, Wang SJ, Rong FL, Dong JG, Cai XH*, Zhou EM*. Immune Responses in Piglets Infected with Highly Pathogenic Porcine Reproductive and Respiratory Syndrome. Vet Immunol Immunopathol. 2011, 142(3-4):170-8. (IF=2.076)