博士生导师简介
张健
专业学科：生物化学与分子生物学
研究方向：植物分子生物学与基因工程

张健，男，汉族，湖南宁远人，1979年生，理学博士，现为中国水稻所研究员。主要研究方向为：
水稻生殖发育相关基因的克隆与功能研究。
水稻胚乳生物反应器与合成生物学。
工作经历
2013年7月至今：中国水稻研究所，水稻生物学国家重点实验室，研究员/课题组长。
2011年11月至2013年6月：美国密西西比州立大学，生物化学、分子生物学、植病与昆虫系，助理研究教授 （Assistant Research Professor）。
2008年1月至2011年11月：美国密西西比州立大学，生物化学与分子生物学系，博士后研究员（Postdoctoral Research Associate）。
教育背景
2001年9月至2007年10月：华中农业大学作物遗传改良国家重点实验室，生物化学与分子生物学专业，硕博连读研究生，获理学博士学位。
1997年9月至2001年6月： 湖南农业大学植物科技学院农学专业，本科生，获农学学士学位。
已发表论文（*corresponding author, # equal contribution）
Hou, Y#., Wang, Y#., Tang, L., Tong, X., Wang, L., Liu, L., Huang, S*. and Zhang, J*. (2019) SAPK10-mediated phosphorylation on WRKY72 releases its suppression on jasmonic acid biosynthesis and bacterial blight resistance. iScience, 16, 499-510.
Liu, X., Li, Z., Hou, Y., Wang, Y., Wang, H., Tong, X., Ao, H. and Zhang, J*. (2019) Protein Interactomic Analysis of SAPKs and ABA-Inducible bZIPs Revealed Key Roles of SAPK10 in Rice Flowering. International journal of molecular sciences, 20.
Ni, S., Li, Z., Ying, J., Zhang, J*. and Chen, H*. (2019) Decreased Spikelets 4 Encoding a Novel Tetratricopeptide Repeat Domain-Containing Protein Is Involved in DNA Repair and Spikelet Number Determination in Rice. Genes, 10.
Bello, B., Hou, Y., Zhao, J.; Jiao, G.; Wu, Y.; Wang, Y., Li, Z., Wang, Y., Tong, X., Wang, W., Yuan, W., Wei, X.; and Zhang, J*. (2018) NF-YB1-YC12-bHLH144 complex directly activates Wx to regulate grain quality in rice (Oryza sativa L.). Plant Biotechnology Journal, 17, 1222-1235.
Tong, X., Wang, Y., Sun, A., Bello, B., Ni, S., and Zhang, J*. (2018) Notched belly grain 4, a novel allele of Dwarf 11, regulates grain shape and seed germination in rice (Oryza sativa L.). International journal of molecular sciences, 19, 4069.
Li, Z., Wang, Y., Bello, B., Ajadi, A., Tong, X., Chang, Y. and Zhang, J*. (2018) Construction of a Quantitative Acetylomic Tissue Atlas in Rice (Oryza sativa L.). Molecules, 23, 2483.
Xiang, J., Wu, H., Zhang, Y., Zhang, Y., Wang, Y., Li, Z., Lin, H., Chen, H. *#, Zhang, J*# and Zhu, D*#. (2017) Transcriptomic Analysis of Gibberellin- and Paclobutrazol-Treated Rice Seedlings under Submergence. International journal of molecular sciences, 18, 2225.
Wang, Y., Lin, H., Tong, X., Hou, Y., Chang, Y. and Zhang, J*. (2017) DNA demethylation activates genes in seed maternal integument development in rice (Oryza sativa L.). Plant Physiology and Biochemistry, 120, 169-178.
Zhong, M., Li, S., Huang, F., Qiu, J., Zhang, J., Sheng, Z., Tang, S., Wei, X. and Hu, P. (2017) The Phosphoproteomic Response of Rice Seedlings to Cadmium Stress. International journal of molecular sciences, 18, 2055.
Wang, Y., Hou, Y., Qiu, J., Li, Z., Zhao, J., Tong, X. and Zhang, J*. (2017) A Quantitative Acetylomic Analysis of Early Seed Development in Rice (Oryza sativa L.). International journal of molecular sciences, 18, 1376.
Hou, Y., Qiu, J., Wang, Y., Li, Z., Zhao, J., Tong, X., Lin, H. and Zhang, J*. (2017) A quantitative proteomic analysis of brassinosteroid-induced protein phosphorylation in rice (Oryza sativa L.). Frontier in Plant Science. 8, 514.
Wang, Y.; Tong, X.; Qiu, J.; Li, Z.; Zhao, J.; Hou, Y., Tang, L. and Zhang, J*. (2017) A phosphoproteomic landscape of rice (Oryza sativa L.) tissues. Physiologia Plantarum. 160, 458–475.
Ying, J.; Zhao, J.; Hou, Y.; Wang, Y.; Qiu, J.; Li, Z.; Tong, X.; Shi, Z.; Zhu, J. and Zhang, J*. (2017) Mapping the N-linked glycosites of rice (Oryza sativa L.) germinating embryos. PloS ONE, 12, (3), e**.
Qiu, J., Hou, Y., Wang, Y., Li, Z., Zhao, J., Tong, X., Lin, H., Wei, X., Ao, H. and Zhang, J*. (2017) A comprehensive proteomic survey of ABA-induced protein phosphorylation in rice (Oryza sativa L.). International Journal of Molecular Sciences, 18, 60.
Li, Z., Tang, L., Qiu, J., Zhang, W., Wang, Y., Tong, X., Wei, X., Hou, Y. and Zhang, J*. (2016) Serine carboxypeptidase 46 Regulates Grain Filling and Seed Germination in Rice (Oryza sativa L.). PloS ONE, 11, e**.
Qiu, J., Hou, Y., Tong, X., Wang, Y., Lin, H., Liu, Q., Zhang, W., Li, Z., Nallamilli, B.R. and Zhang, J*. (2016) Quantitative phosphoproteomic analysis of early seed development in rice (Oryza sativa L.). Plant molecular biology, 90, 249-265.
Hou, Y., Qiu, J., Tong, X., Wei, X., Nallamilli, B.R., Wu, W., Huang, S*. and Zhang, J*. (2015) A comprehensive quantitative phosphoproteome analysis of rice in response to bacterial blight. BMC plant biology, 15, 163.
Hou, Y., Wang, L., Wang, L., Liu, L., Li, L., Sun, L., Rao, Q., Zhang, J*. and Huang, S*. (2015) JMJ704 positively regulates rice defense response against Xanthomonas oryzae pv. oryzae infection via reducing H3K4me2/3 associated with negative disease resistance regulators. BMC plant biology, 15, 286.
Chen, Z., Gao, X. and Zhang, J. (2015) Alteration of osa-miR156e expression affects rice plant architecture and strigolactones (SLs) pathway. Plant cell reports, 34, 767-781.
Nallamilli, B.R., Edelmann, M.J., Zhong, X., Tan, F., Mujahid, H., Zhang, J., Nanduri, B. and Peng, Z. (2014) Global analysis of lysine acetylation suggests the involvement of protein acetylation in diverse biological processes in rice (Oryza sativa). PloS ONE, 9, e89283.
Zhang, J., Mujahid, H., Hou, Y., Nallamilli, B.R. and Peng, Z. (2013) Plant long non-coding RNA: a new frontier of gene regulation. 2013. American Journal of Plant Sciences. American Journal of Plant Sciences, 4, 1038-1045.
Mujahid, H., Tan, F., Zhang, J., Nallamilli, B.R., Pendarvis, K. and Peng, Z. (2013) Nuclear proteome response to cell wall removal in rice (Oryza sativa). Proteome science, 11, 26.
Nallamilli, B.R., Zhang, J., Mujahid, H., Malone, B.M., Bridges, S.M. and Peng, Z. (2013) Polycomb group gene OsFIE2 regulates rice (Oryza sativa) seed development and grain filling via a mechanism distinct from Arabidopsis. PLoS genetics, 9, e**.
Yang, J., Wang, J., Fan, J., Zhu, J.Y., Chen, T., Wang, C.L., Zheng, T.Q., Zhang, J. and Zhong, W.G. (2013) Development of AS-PCR marker based on a key mutation confirmed by re-sequencing of Wx-mp in Milk Princess and its application in japonica soft rice (Oryza sativa L.) breeding. Plant Breeding, 132, 595-603.
Gao, X., Chen, Z., Zhang, J., Li, X., Chen, G., Li, X. and Wu, C. (2012) OsLIS-L1 encoding a lissencephaly type-1-like protein with WD40 repeats is required for plant height and male gametophyte formation in rice. Planta, 235, 713-727.
Zhang, J., Nallamilli, B.R., Mujahid, H. and Peng, Z. (2010) OsMADS6 plays an essential role in endosperm nutrient accumulation and is subject to epigenetic regulation in rice (Oryza sativa). The Plant journal, 64, 604-617.
Zhang, J#., Guo, D#., Chang, Y., You, C., Li, X., Dai, X., Weng, Q., Zhang, J., Chen, G., Li, X., Liu, H., Han, B., Zhang, Q. and Wu, C. (2007) Non-random distribution of T-DNA insertions at various levels of the genome hierarchy as revealed by analyzing 13 804 T-DNA flanking sequences from an enhancer-trap mutant library. The Plant journal, 49, 947-959.
会议报告
Jian Zhang. NF-YB1-YC12-bHLH144 complex directly activates Wx to regulate grain quality in rice (Oryza sativa L.). The 4th International Rice Congress，Oct 14-17, 2018, in Singapore.
张健. NF-YB1-YC12-bHLH144 complex directly activates Wx to regulate grain quality in rice (Oryza sativa L.). 浙江省生物化学与分子生物学学会，2018年8月24-27日，浙江舟山.
Jian Zhang and Zhaohua Peng. OsMADS6 plays an essential role in flower development and endosperm nutrient accumulation and is subject to epigenetic regulation in rice (Oryza sativa). Rice Technical Work Group 33rd meeting, February 22-25, 2010, in Biloxi, Mississippi, U.S.A.
课题资助
中国水稻研究所“青年英才计划”启动基金，100万元，主持，2013-2014。
中国农科院科技创新工程“水稻生殖发育生物学团队”，700万元，主持，2014-2019。
国家自然科学基金青年基金，项目号：**，24万元，主持，2015-2017。
中国农科院科技创新工程“青年英才计划”，300万元，主持，2015-2018。
国家自然科学基金面上项目，项目号：**，59万元，主持，2019-2022。
社会活动与任职
农业部：中国农科院“青年英才”计划（全国重点海外高层次人才引进计划）A类入选人。2013-今。
中国农科院科技创新工程“水稻生殖发育生物学团队”首席专家。2014-2019。
浙江省生物化学与分子生物学学会理事。2018-今。
中国水稻研究所学位委员会委员。2018-今。
“Rice Technical Workers Group” (SERA018, Multistate Research Coordinating Committee and Information Exchange Group, U.S.A)成员。 2012-2013。
受邀为Molecular Plant, The Plant Biotechnology Journal, BMC Genomics, Plos One, Acta Physiologiae Plantarum,等多家主流杂志审稿逾40篇。
通讯地址：浙江省富阳市水稻所路28号 中国水稻研究所 311400
电　　话：, **
电子邮箱：zhangjian@caas.cn
更多信息请查阅实验室主页：http://www.escience.cn/people/cnrriseeddev/index.html