王海洋
王海洋研究员、博士生导师、玉米功能基因组创新团队首席科学家

已发表SCI论文和专著70余篇，并曾以第一作者或通讯作者在Nature、Science和Nature Cell Biology发表论文4篇。研究成果多次受到 F1000 的关注并被评为本领域必读的研究论文。论文已被引用超过2800余次，单篇引用高达300余次。与万建民教授合作，阐明独脚金内酯调控水稻分蘖和株型的信号途径的工作入选2014年度中国科学十大进展。先后主持了美国国家卫生院 (NIH)、美国国家基金会 (NSF)、Triad基金、科技部863科技重大专项等研究项目十余项。目前主持国家自然科学基金重点项目“植物生物钟核心基因CCA1表达调控的分子机理研究”。
主要履历及经历：
1986－1998年在杭州大学（现浙江大学）、西北大学和密执根大学分别获得学士、硕士和博士学位。
1998－2002年在耶鲁大学分子细胞发育生物学系从事博士后研究工作。
2002－2013年分别在美国康奈尔大学Boyce Thompson Institute for Plant Research （2002－2009） 和耶鲁大学（2009－2013）担任独立课题负责人。
2009－2013年还兼任国家作物分子设计工程技术研究中心副主任。
2013年作为海外高层次人才引进到中国农业科学院生物技术研究所担任研究员。

社会兼职：
“BMC Research Notes”、《农业生物技术学报》副主编和
《World Journal of Biological Chemistry》编委。
研究领域：
长期从事植物光信号和激素信号转导分子机理的研究。近年来，开展了作物理想株型分子设计和杂交育种技术等方面的研究。作为玉米功能基因组创新团队首席科学家，将带领团队探索高效协同创新机制，聚焦玉米高产耐密遗传基础和分子机理解析，开展玉米耐密理想株型的分子设计，创制优异遗传育种材料，为我国未来玉米种业和产业发展提供支撑和引领作用。
发表论文：
代表性论文：（2010－2015 年, *通讯作者）
1.Li, J., Li, G., Gao, S., Martinez, C., He, G., Zhou, Z., Huang, X., Lee, J.-H., Zhang, H., Shen, Y., Wang, H. and Deng, X.W. 2010. Arabidopsis transcription factor ELONGATED HYPOCOTYL 5 plays a role in the feedback control of phytochromeA signaling. Plant Cell, 22: 3634-3649.
2.Liu X, Guo T, Wan X, Wang H, Zhu M, Li A, Su N, Shen Y, Mao B, Zhai H, Mao L, Wan J. 2010. Transcriptome analysis of grain-filling caryopses reveals involvement of multiple regulatory pathways in chalky grain formation in rice.BMC Genomics 30;11:730.
3.Li, G., Siddiqui, H., Teng, Y., Lin, R., Wan, X.Y., Li, J., Lau, O.S., Ouyang, X., Dai, M., Wan, J., Devlin, P., Deng, X.W., Wang*, H. 2011. Coordinated Transcriptional Regulation Underlying the Circadian Clock in Arabidopsis. Nature Cell Biology, 13, 616-622.(Cited by F1000)
4.Ouyang X, Li J, Li G, Li B, Chen B, Shen H, Huang X, Mo X, Wan X, Lin R, Li S, Wang H, Deng XW. 2011. Genome-Wide Binding Site Analysis of FAR-RED ELONGATED HYPOCOTYL3 Reveals Its Novel Function in Arabidopsis Development.Plant Cell. 23: 2514-2535.
5.Zhou S, Wang Y, Li W, Zhao Z, Ren Y, Wang Y, Gu S, Lin Q, Wang D, Jiang L, Su N, Zhang X, Liu L, Cheng Z, Lei C, Wang J, Guo X, Wu F, Ikehashi H, Wang H, Wan J. 2011. Pollen semi-sterility1 encodes a kinesin-1-like protein important for male meiosis, anther dehiscence, and fertility in rice.Plant Cell, 23:111-29.
6.Lin, Q, Wang, D, Dong, H, Gu, S, Cheng, Z, Gong, J, Qin, R, Jiang, L, Li,G, Wang, J.L, Wu, F, Guo, X, Zhang, X, Lei, C, Wang, H, Wan, J. (2012). Rice APC/CTEcontrols tillering through mediating the degradation of MONOCULM 1. Nature Communications, 3:752 | DOI: 10.1038/ncomms1716.
7.Mao B, Cheng Z, Lei C, Xu F, Gao S, Ren Y, Wang J, Zhang X, Wang J, Wu F, Guo X, Liu X, Wu C, Wang H, Wan J. 2012. Wax crystal-sparse leaf2, a rice homologue of WAX2/GL1, is involved in synthesis of leaf cuticular wax.Planta, 235:39-52.
8.Su, N., Hu, M.L., Wu, D.X., Wu, F.Q., Fei, G.L., Lan, Y., Chen, X.L., Shu, X.L., Zhang, X., Guo, X.P., Cheng, Z.J., Lei, C.L., Qi, C.K., Jiang, L., Wang, H. and Wan, J.M. 2012.Disruption of a Rice Pentatricopeptide Repeat Protein Causes a Seedling-Specific Albino Phenotype and Its Utilization to Enhance Seed Purity in Hybrid Rice Production.Plant Physiol. 159: 227-238.
9.Dai M, Zhang C, Kania U, Chen F, Xue Q, Mccray T, Li G, Qin G, Wakeley M, Terzaghi W, Wan J, Zhao Y, Xu J, Friml J, Deng X, and Wang* H. 2012. A PP6-type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis. Plant Cell. 24: 2497-514.
10.Sassi M, Lu Y, Zhang Y, Wang J, Dhonukshe P, Blilou I, Dai M, Li J, Gong X, Jaillais Y, Yu X, Traas J, Ruberti I, Wang H, Scheres B, Vernoux T, Xu J. 2012. COP1 mediates the coordination of root and shoot growth by light through modulation of PIN1- and PIN2-dependent auxin transport in Arabidopsis.Development. 139(18): 3402-12.
11.Tang, W., Wang, W., Chen, D., Ji, Q., Jing, Y., Wang, H and Lin, R. 2012. Transposase-derived Proteins FHY3/FAR1 Interact with PIF1 to Regulate Chlorophyll Biosynthesis by Controlling HEMB1 Gene during Deetiolation in Arabidopsis. Plant Cell, 24: 1984-2000.
12.Gao, H., Zheng, X.M., Fei, G., Chen, J., Jin, M., Ren, Y., Wu, W., Zhou, F., Wang, J., Zhang, X., Guo, X., Wang, J.L., Cheng, Z.J., Wu, C., Wang, H., Wan, J.M. 2012. Ehd4 encodes a novel and oryza-genus specific regulator of photoperiodic flowering in rice.Plos Genetics, 9(2)e**.
13.Jiang, X., Li, H., Wang, T., Peng, C., Wang, H., Wu, H., and Wang, X. 2012.Gibberellin indirectly promotes chloroplast biogenesis as a means to maintain the chloroplast population of expanded cells.Plant J.72: 768-780. Article first published online: 1 OCT 2012, DOI: 10.1111/j.1365-313X.2012.05118.x (cited by F1000).
14.Zhang,L., Cheng,Z., Qin,R., Qiu,Y., Wang,J.L., Cui,X., Gu,L., Zhang,X., Guo,X., Wang, D., Jiang,L., Wu,C.Y., Wang, H., Cao,X., and Wan, J., 2012. Identification and Characterization of an Epi-allele of OsFIE1 Reveals a Regulatory Linkage between two Epigenetic Marks in Rice. Plant Cell 24, 4407-4421.
15.Wu,W.,Zheng,X.M.,Lu,G.W., Zhong,Z.Z., Gao,H., Chen,L.P., Jiang,L., Wu,C.Y., Wang,H.J., Wang,Q., Zhou,K.N., Wang,J.L., Wu,F.Q.,Zhang,X., Guo,X.P., Cheng,Z.J.,Lei,C.L., Lin,Q.B., Wang, H., Ge, S., Wan, J. 2013. The association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia. PNAS, 110, 2775-2780.
16.Ma, X., Cheng, Z., Qin, R., Qiu, Y., Heng, Y., Yang, H., Ren, Y., Wang, X., Bi, J., Ma, X., Zhang, X., Wang, J., Lei, C., Guo, X., Wang, J., Wu, F., Jiang, L., Wang, H., Wan, J. 2013. OsARG encodes an arginase that plays critical roles in panicle development and grain production in rice. Plant J.73, 190-200. Published online DOI: 10.1111/j.1365-313X.2012.05122.x
17.Dai M, Terzaghi W, and Wang* H. 2013. Multifaceted roles of Arabidopsis PP6 phosphatase in regulating cellular signaling and plant development. Plant Signaling & Behavior. 8:1, 1-5.
18.Dai M, Xue Q, Mccray T, Chen F, Margavage K, Lee J, Nezames C, Guo L, Terzaghi W, Wan J, Deng XW, Wang* H. 2013. The Arabidopsis PP6 Phosphatase Regulates ABI5 Phosphorylation and ABA Signaling. Plant Cell, 25:517-534.
19.Zheng, X., Wu, S., Zhou, P., Song, M., Xi, Y., Li, Z., Cai, Y., Meng, F., Yang, L. Wang, H., Zhai, H., Yang, J. 2013. Arabidopsis Phytochrome B Promotes SPA1 Nuclear Accumulation to Repress Photomorphogenesis Under Far-red Light. Plant Cell, 25:115-133.
20.Liu, F., Ren, Y., Wang, Y., Peng, C., Zhou, K., Lv, J., Guo, X., Zhang, X., Zhong, M., Zhao, S., Jiang, L., Wang, H., Bao, Y., Wan, J. 2013. OsVPS9A functions cooperatively with OsRAB5A to regulate post-Golgi dense vesicle-mediated storage protein trafficking to the protein storage vacuole in rice endosperm cells. Molecular Plant 6(6):1918-32. doi: 10.1093/mp/sst081. Epub 2013 May 30.
21.Zhao, Z., Zhang, Y., Liu, X., Zhang, X., Liu, S., Yu, X., Ren, Y., Zheng, X., Wang, C., Zhou, K., Bian, X., Jiang, L., Chen, L., Liu, S., Guo, X., Wang, J., Jiang, X., Wu, C., Zhai, H., Wang, H., Wan, J. 2013. A role for a dioxygenase in auxinmetabolism and seeddevelopment in rice. Developmental Cell 2013 Oct 14;27(1):113-22. doi: 10.1016/j..
22.Fan, L., Hao, H., Xue, Y., Zhang, L., Song, K., Ding, Z., Botella, M. A., Wang, H., Lin, L. 2013.Dynamic analysis of Arabidopsis AP2 σ reveals its key role in clathrin-mediated endocytosis and plant development. Development140(18):3826-37. doi: 10.1242/dev.095711. Epub 2013 Aug 7.
23.Dong, H., Fei, G-L., Wu, C-Y.,Wu,F-Q., Sun,Y.Y., Chen,M-J., Ren,Y-L., Zhou,K-N., Cheng, Z-J., Wang, J-L., Jiang, L., Zhang, X., Guo, X-P., Lei, C-L., Su, N., Wang, H., Wan, J-M., 2013. A Rice Virescent-Yellow Leaf Mutant Reveals New Insights into the Role and Assembly of Plastid Clp Protease in Higher Plants. Plant Physiol.162(4):1867-80. doi: 10.1104/pp.113.217604.
24.Tang, W., Ji, Q., Huang, Y., Jiang, Z., Bao, M., Wang, H., Lin, R. 2013. FHY3 and FAR1 Transcription factors integrate light and abscisic acid signaling in Arabidopsis. Plant Physiol.163(2):857-66. doi: 10.1104/pp.113.224386.
25.Zhou, F., Lin, Q., Zhu, L., Ren, Y., Zhou, K., Shabek, N., Wu, F., Dong, W., Gan, L., Gao, H., Ma, W., et al., Wang*, H., Zheng*, N., Wan*. J. 2013. Degradation of D53 repressor by the D14-SCF D3 complex is essential for strigolactone signaling.Nature(Research article) 504(7480):406-10. doi: 10.1038/nature12878. Epub 2013 Dec 11. (* co-corresponding author)
26.Ren,Y., Wang,Y., Liu,F., Zhou,K., Liu,K., Zhou,F., Wang,Y., Zhang,X., Guo,X., Jiang,L., Wu,C., Bao,Y., Wang, H., Wan, J. (2014). Glutelin Precursor Accumulation3 Encodes a Regulator of Post-Golgi Vesicular Traffic Essential for Vacuolar Storage Protein Sorting in Rice Endosperm. Plant Cell,26(1):410-25. doi: 10.1105/tpc.113.121376. Epub 2014 Jan 31.
27.Lu,G., Wu,F., Wu,W., Wang,H.J., Zhang,Y., Chen,X., Xu,J., Wei,X., Yu,C., Ren,Y., Zhou,K., Gao,H., Chen,S., Wang,J.L., Zhang,X., Guo,X.,Cheng,Z.J.,Lei,C., Li,X., Jiang,L., Wang, H., Wan, J. (2014). Rice LTG1 is involved in adaptive growth and fitness under low ambient temperature. Plant J.78(3):468-80.
28.Tan J, Tan Z, Wu F, Sheng P, Heng Y, Wang X, Ren Y, Wang J, Guo X, Zhang X, Cheng Z, Jiang L, Liu X, Wang H, Wan J. (2014) A novel chloroplast-localized pentatricopeptide repeat protein involved in splicing affects chloroplastdevelopment and abiotic stress response in rice.Mol Plant, 7(8):1329-49.
29.Wang Q, Liu Y, He J, Zheng X, Hu J, Liu Y, Dai H, Zhang Y, Wang B, Wu W, Gao H, Zhang Y, Tao X, Deng H, Yuan D, Jiang L, Zhang X, Guo X, Cheng X, Wu C, Wang H,Yuan L, Wan J. (2014). STV11 encodes a sulphotransferase and confers durable resistance to rice stripe virus.Nat Communications, 9;5:4768. doi: 10.1038/ncomms5768.
30.Liu, Y., Wu, H., Chen, H., Liu, Y. J., et.al. Wu, C., Wang, H., Wan, J. (2014) A gene cluster encoding lectin receptor kinases confers broad-spectrum and durable insect resistance in rice. Nature Biotechnology 2015 Mar;33(3):301-5. doi: 10.1038/nbt.3069. Epub 2014 Dec 8. 2014 Dec 8. doi: 10.1038/nbt.3069.
31.Gao, H., Jin, M.-N., Zheng, X.-M., Chen, J., Yuan, D., Wang, M., Huang, D., Zhang, Z., Zhou, K., Sheng, P., Ma, J., Ma, W., Deng, H., Jiang, L., Liu, S., Wang, H., Wu, C., Yuan, L., Wan, J., (2014). Days to heading 7, a major quantitative locus determining photoperiod sensitivity and regional adaptation in rice.PNAS 2014 Nov 18;111(46):16337-42. doi: 10.1073/pnas..
32.Sun H, Guo Z, Gao L, Zhao G, Zhang W, Zhou R, Wu Y, Wang H, An H, Jia J. DNA methylation pattern of Photoperiod-B1 is associated with photoperiod insensitivity in wheat (Triticumaestivum). New Phytol. 2014 Nov; 204(3):682-92.
33.Wang, H. and Wang*, H. (2014). Phytochrome signaling: Time to tighten up the loose ends. Mol. Plant 2015 Apr;8(4):540-51. doi: 10.1016/j.molp.2014.11.021. Epub 2014 Dec 24
34.Wang, H. and Wang*, H. (2014). The miR156/SPL module, a signaling hub and versatile toolbox that gears up crops for enhanced agronomic traits. Mol. Plant 2015 May;8(5):677-88. doi: 10.1016/j.molp.2015.01.008. Epub 2015 Jan 21.
35.Wang, H and Wang*, H. Multifaceted roles of FHY3 and FAR1 in light signaling and beyond. Trends in Plant Science2015 Jul;20(7):453-61. doi: 10.1016/j.tplants.2015.04.003. Epub 2015 May 5.
36.Lin Q, Wu F, Sheng P, Zhang Z, Zhang X, Guo X, Wang J, Cheng Z, Wang J, Wang H, Wan J. The SnRK2-APC/C(TE) regulatory module mediates the antagonistic action of gibberellic acid and abscisic acid pathways. Nat Commun. 2015 Aug 14;6:7981. doi: 10.1038/ncomms8981.




?