博士 教授 硕士生导师
通讯地址：北京市海淀区阜成路33号 北京工商大学理学院
邮编：100048
电子信箱：jinjianming@btbu.edu.cn
电话：
个人简历：
1993年毕业于武汉大学生命科学学院生物化学专业，获理学学士学位；
1997年毕业于武汉大学生命科学学院生物化学专业，获理学硕士学位；
2002年毕业于中国科学院昆明植物研究所植物化学专业，获理学博士学位；
1993年至1994年在浙江永宁药业股份有限公司工作；
1997年至1999年中国科学院水生生物研究所工作；
2002年至2009年在韩国首尔大学农学与生命科学学院从事研究工作；
2009年至2010年在香港浸会大学生物学从事研究工作；
2010年至2011年在美国奥克拉荷马大学从事研究研究；
2011年至2012年在云南民族大学化学与生物技术学院工作；
2012年至今在北京工商大学理学院工作。
主要研究领域：
植物原料活性成分及其功效评价，活性成分的生物合成及其功效评价。
主要研究内容：
1.化妆品植物原料的提取分离工艺和功能性活性成分研究
2.植物原料的生物转化技术研究
3.基因工程高效合成活性成分及其功效评价研究
4.芦荟产品的质量安全研究
主要学术成就：
现主持二项国家自然科学基金和一项北京市自然科学基金。
发表论文：
1.Wei Chen, Jun Yao, Jie Meng, Wenjing Han, Yong Tao, Yihua Chen, Yixin Guo, Guizhi Shi, Yang He, Jian-Ming Jin* and Shuang-Yan Tang*. Promiscuous enzymatic activity-aided multiple-pathway network design for metabolic flux rearrangement in hydroxytyrosol biosynthesis. Nature Communications, 2019, 10: 960.
2.Chen Wei, Zhang Xuanxuan, Xiong Dandan, Jin Jian-Ming* and Tang Shuang-Yan*. Engineering the effector specificity of regulatory proteins for the in vitro detection of biomarkers and pesticide residues. Applied Microbiology and Biotechnology, 2019, 103(7): 3205–3213.
3.Heng Li, Jing Li, Ruinan Jin, Wei Chen, Chaoning Liang, Jieyuan Wu, Jian-Ming Jin, Shuang-Yan Tang*. Towards the construction of high-quality mutagenesis libraries. Biotechnology Letter, 2018, 40: 1101–1107.
4.Heng Li, Wei Chen, Rui-Nan Jin,Jian-Ming Jin*, Shuang-Yan Tang*. Biosensor?aided high?throughput screening of hyper?producing cells for malonyl?CoA?derived products. Microbial Cell Factories, 2017, 16: 187.
5.Heng Li, Chaoning Liang, Wei Chen, Jian-Ming Jin*, Shuang-Yan Tang*, Yong Tao. Monitoring in vivo metabolic flux with a designed whole-cell metabolitebiosensor of shikimic acid. Biosensors and Bioelectronics, 2017, 98: 457–465.
6.Jieyuan Wu, Peixia Jiang, Wei Chen, Dandan Xiong, Linglan Huang, Junying Jia, Yuanyuan Chen, Jian-Ming Jin*, Shuang-Yan Tang*. Design and application of a lactulose biosensor. Scientific Reports, 2017, 7: 45994.
7.Dandan Xiong, Shikun Lua, Jieyuan Wu, Chaoning Liang, Wei Wang, Wenzhao Wang, Jian-Ming Jin*, Shuang-Yan Tang*. Improving key enzyme activity in phenylpropanoid pathway with a designed biosensor. Metabolic Engineering, 2017, 40: 115-123.
8.You-Hai Li, Wen-Jin Han, Xi-Wu Gui, Tao Wei, Shuang-Yan Tang, Jian-Ming Jin*. Putative nonribosomal peptide synthetase and cytochrome P450 genes responsible for tentoxin biosynthesis in Alternaria alternata ZJ33. Toxins, 2016, 8: 234.
9.Chaoning Liang, Yi Zhang, Yan Jia, Wenzhao Wang, Youhai Li, Shikun Lu, Jian-Ming Jin*, Shuang-Yan Tang*. Engineering a carbohydrate-processing transglycosidase into glycosyltransferase for natural product glycodiversification. Scientific Reports, 2016, 6: 21051.
10.Lin Zhu, Zhe Wu, Jian-Ming Jin, Shuang-Yan Tang*. Directed evolution of leucine dehydrogenase for improved efficiency of l-tert-leucine synthesis. Applied Microbiology and Biotechnology, 2016, 100: 5805–5813.
11.Peixia Jiang, Shanshan Mu, Heng Li, Youhai Li, Congmin Feng, Jian-Ming Jin* and Shuang-Yan Tang*. Design and application of a novel high-throughput screening technique for 1-deoxynojirimycin. Scientific Reports, 2015, 5: 8563.
12.Hokyoung Son, Young-Su Seo, Kyunghun Min, Ae Ran Park, Jungkwan Lee, Jian-Ming Jin, Yang Lin, Peijian Cao, Sae-Yeon Hong, Eun-Kyung Kim, Seung-Ho Lee, Aram Cho, Seunghoon Lee, Myunggu Kim, Yongsoo Kim, Jung-Eun Kim, Jin-Cheol Kim, Gyung Ja Choi, Sung-Hwan Yun, Jae Yun Lim, Minkyun Kim, Yong-Hwan Lee, Yang-Do Choi, Yin-Won Lee*. A phenome-based functional analysis of transcription factors in the cereal head blight Fungus, Fusarium graminearum. PLoS Pathogens, 2011, 7: e**.
13.Jian-Ming Jin, Seunghoon Lee, Jungkwan Lee, Seung-Ryul Baek, Jin-Cheol Kim, Sung-Hwan Yun, Sook-Toung Park, Seogchan Kang and Yin-Won Lee*. Functional characterization and manipulation of the apicidin biosynthetic pathway in Fusarium semitectum. Molecular Microbiology. 2010, 76: 456-466.
14.Jian-Ming Jin, Jung-Kuan Lee and Yin-Won Lee*. Characterization of the carotenoid biosynthetic genes in the ascomycete Gibberella zeae. FEMS Microbiology Letters. 2010, 320: 197-202.
15.Ju-Young Park, Jianming Jin, Yin-Won Lee, Seogchan Kang, and Yong-Hwan Lee*. Rice blast fungus Magnaporthe oryzae infects Arabidopsis thaliana via a distinct mechanism from that required for the infection of rice. Plant Physiology, 2009, 149: 474-486.
16.Jianming Jin, Seung-Ryul Baek, Kyung-Rim Lee, Jung-kwan Lee, Sung-Hwan Yun, Seogchan Kang and Yin-Won Lee*. Purification and phytotoxicity of apicidins produced by the Fusarium semitectum KCTC16676. The Plant Pathology Journal, 2008, 24: 385-388.
17.Jung-Eun Kim, Jin-Cheol Kim, Jianming Jin, Sung-Hwan Yun and Yin-Won Lee*. Functional characterization of genes located at the aurofusarin biosynthesis gene cluster in Gibberella zeae. The Plant Pathology Journal, 2008, 24: 8-16.
18.Jung-Eun Kim, Jianming Jin, Hun Kim, Jin-Cheol Kim, Sung-Hwan Yun, and Yin-Won Lee*. GIP2, a Putative Transcription Factor That Regulates the Aurofusarin Biosynthetic Gene Cluster in Gibberella zeae. Applied and Environmental Microbiology, 2006, 72: 1645-1652.
19.Yong-Tae Kim, Ye-Ryun Lee, Jianming Jin, Kap-Hoon Han, Hun Kim, Jin-Cheol Kim, Theresa Lee, Sung-Hwan Yun, and Yin-Won Lee*. Two different polyketide synthase genes are required for synthesis of zearalenone in Gibberella zeae. Molecular Microbiology, 2005, 58: 1102–1113.
20.Jung-Eun Kim, Kap-Hoon Han, Jianming Jin, Hun Kim, Jin-Cheol Kim, Sung-Hwan Yun and Yin-won Lee*. Putative polyketide synthase and laccase genes for biosynthesis of aurofusarin in Gibberella zeae. Applied and Environmental Microbiology, 2005, 71: 1701-1708.
21.Yung-Jin Chang, Jian-Ming Jin, Hee-Young Nam and Soo-Un Kim*. Point mutation of (+)-germacrene A synthase from Ixeris dentate. Biotechnology Letters, 2005, 27: 285-288.
22.Min-Young Kim, Yung-Jin Chang, Myun-Ho Bang, Nam-In Baek, Jian-Ming Jin, Cheol-Ho Lee and Soo-Un Kim*. cDNA isolation and characterization of (+)-germacrene A synthase from Ixeris dentate form. Albiflora Hara. Journal of Plant Biology, 2005, 48: 178-186.
23.Jian-Ming Jin, Yin-Jun Zhang, Hai-zhou Li and Chong-ren Yang*. Cytotoxic steroidal saponins from Polygonatum zanlanscianense. Journal of Natural Products, 2004, 67: 1992-1995.
24.Jian-Ming Jin, Ying-Jun Zhang, and Chong-Ren Yang*. Four new steroid constituents from the waste residue of fibre separation from Agave americana leaves. Chemical & Pharmaceutical Bulletin, 2004, 52: 654-658.
25.Jian-Ming Jin, Ying-Jun Zhang, and Chong-Ren Yang*. Spirostanol and furostanol glycosides from the fresh tubers of Polianthes tuberosa. Journal of Natural Products, 2004, 67: 5-9.
26.Jian-Ming Jin, Xi-Kui Liu, and Chong-Ren Yang*. Three new hecogenin glycosides from fermented leaves of Agave americana. Journal of Asian natural products Research, 2003, 5: 95-103.
27.Jianming Jin, and Chongren Yang*. Two new steroidal sapogenins from fermented leaves of Agave americana. Chinese Chemical Letters, 2003, 14: 491-494.
28.Jianming Jin, Xikui Liu, and Chongren Yang*. A new cholestane glycoside from the tubers of Polianthes tuberosa. Acta Botanica Yunnanica, 2003, 25: 107-110.
29.JIN Jian-Ming, LIU Xi-kui, TENG Rong-Wei and YANG Chong-Ren*. Enzymatic degradation of parvifloside. Acta Botanica Sinica, 2002, 44: 1243-1249.
30.Jianming Jin, Xikui Liu, Rongwei Teng and Chongren Yang*. Two new steroidal glycosides from fermented leaves of Agave americana. Chinese Chemical Letters, 2002, 13: 629-632.
31.Jianming Jin, Xikui Liu, and Chongren Yang*. A new steroidal saponin from fermented leaves of Agave americana. Acta Botanica Yunnanica, 2002, 24: 539-542.
32.Jianming Jin, Xikui Liu, and Chongren Yang*. A new pregnane glycoside from fermented leaves of Agave americana. Chinese Chemical Letters, 2002, 13: 1189-1192.