博士副研究员
通讯地址：北京工商大学理学院
邮编：100048
电子信箱：liulei@btbu.edu.c
个人简历
1998.09 - 2002.07 中国农业大学生物学院生物科学专业学士
2002.09 - 2007.07 中国农业大学生物学院生理学博士
2007.07 - 2011.12 中国科学院动物研究所助理研究员
2012.01 - 2015.07 中国科学院动物研究所副研究员
2015.08 至今北京工商大学理学院副研究员
研究领域
动物细胞模型在化妆品功效及安全性评价中的应用
学术成就
主要从事细胞生物学及发育生物学研究，利用细胞模型开展细胞干性、发育潜能研究及应用安全性评估，并对其调控自我更新和分化的分子机制进行探索。工作期间共发表SCI论文17篇，以第一或共同第一作者发表论文3篇（第一作者影响因子共计21.776），先后主持4项国家级项目，申请发明专利1项。
发表论文
1. Li Z, Wang L, Wang Y, Liu L, Wang L, Li W, Zhou Q. Generation of an LncRNA Gtl2-GFP Reporter for Rapid Assessment of Pluripotency in Mouse Induced Pluripotent Stem Cells. J Genet Genomics. 20;42(3) (2015):125-8. IF=2.924
2. Guo CL#, Liu L#, Jia YD, Zhao XY, Zhou Q, Wang L*. A novel variant of Oct3/4 gene in mouse embryonic stem cells. Stem Cell Research9(2) (2012):69-76.（共同第一作者）IF=4.467
3. Li W#, Shuai L#, Wan HF#, Dong MZ#, Wang M, Sang LS, Feng CJ, Luo GZ, Li TD, Li X, Wang LB, Zheng QY, Sheng C, Wu HJ, Liu ZH, Liu L, Wang L, Wang XJ, Zhao XY*, Zhou Q*. Androgenetic haploid embryonic stem cells produce live transgenic mice. Nature 490(7420) (2012):407-411. IF=42.351
4. Sheng C#, Zheng QY#, Wu JY#, Xu Z, Sang LS, Wang LB, Guo CL, Zhu WW, Tong M, LiuL, Li W, Liu ZH, Zhao XY, Wang L, Chen ZG*, Zhou Q*. Generation of dopaminergic neurons directly from mouse fibroblasts and fibroblast-derived neural progenitors. Cell Research22(4)(2012):769-772. IF=11.981
5. Sheng C#, Zheng QY#, Wu JY#, Xu Z, Wang LB, Li W, Zhang HJ, Zhao XY, Liu L, Wang ZW, Guo CL, Wu HJ, Liu ZH, Wang L, He SG, Wang XJ, Chen ZG*, Zhou Q*. Direct reprogramming of sertoli cells into multipotent neural stem cells by defined factors. Cell Research22(1) (2012):208-218. IF=11.981
6. Li TD#, Zhao XY#, Teng F, Li X, Jiang MG, Li W, Wang XP, Wang JL, Liu L, Liu ZH, Wang L, Zhou Q*. Derivation of Germline Competent Rat Embryonic Stem Cells from DA Rats. Journal of Genetics and Genomics39(11) (2012):603-606. IF=2.924
7. Gu Q#, Hao J#, Zhao XY, Li W, Liu L, Wang L, Liu ZH, Zhou Q*. Rapid conversion of human ESCs into mouse ESC-like pluripotent state by optimizing culture conditions. Protein & Cell 3(1) (2012):71-79. IF=3.22
8. Tong M#, Lv Z#, Liu L#, Zhu H#, Zheng QY#, Zhao XY, Li W, Wu YB, Zhang HJ, Wu HJ, Li ZK, Zeng FY, Wang L, Wang XJ, Sha JH*, Zhou Q*. Mice generated from tetraploid complementation competent iPS cells show similar developmental features as those from ES cells but are prone to tumorigenesis. Cell Research21(11) (2011):1634-1637.（共同第一作者）IF=11.981
9. Li W#, Zhao XY#, Wan HF, Zhang Y, Liu L, Lv Z, Wang XJ, Wang L*, Zhou Q*. iPS cells generated without c-Myc have active Dlk1-Dio3 region and are capable of producing full-term mice through tetraploid complementation. Cell Research21(3) (2011):550-553. IF=11.981
10. Riaz A#, Zhao XY#, Dai XP#, Li W, Liu L, Wan HF, Yu Y, Wang L, Zhou Q*. Mouse cloning and somatic cell reprogramming using electrofusedblastomeres. Cell Research 21(5) (2011):770-778. IF=11.981
11. Liu L#, Luo GZ#, Yang W#, Zhao XY#, Zheng QY, Lv Z, Li W, Wu HJ, Wang L, Wang XJ*, Zhou Q*. Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. Journal of Biological Chemistry 285(25) (2010):19483-19490. IF=5.328
12. Zhou SY#, Ding CH#, Zhao XY#, Wang EY, Dai XP, Liu L, Li W, Liu ZC, Wan HF, Feng CJ, Hai H, Wang L, Zhou Q*. Successful generation of cloned mice using nuclear transfer from induced pluripotent stem cells. Cell Research20(7) (2010):850-853. IF=11.981
13. Zhao XY#, Li W#, Lv Z#, Liu L, Tong M, Hai T, Hao J, Wang X, Wang L, Zeng FY*, Zhou Q*. Viable fertile mice generated from fully pluripotent iPS cells derived from adult somatic cells. Stem Cell Reviews and Reports 6(3) (2010):390-397. IF=6.774
14. Zhao XY#, Li W#, Lv Z#, Liu L, Tong M, Hai T, Hao J, Guo CL, Wang X, Wang L, Zeng FY*, Zhou Q*. Efficient and rapid generation of induced pluripotent stem cells using alternative culture medium. Cell Research20(3)(2010):383-386. IF=11.981
15. Zhao XY, Lv Z, Liu L, Wang L, Tong M, Zhou Q*. Derivation of embryonic stem cells from Brown Norway rats blastocysts. Journal of Genetics and Genomics37(7) (2010):467-473. IF=2.924
16. Zhao XY#, Li W#, Lv Z#, Liu L, Tong M, Hai T, Hao J, Guo CL, Ma QW, Wang L, Zeng FY*, Zhou Q*. iPS cells produce viable mice through tetraploid complementation. Nature461(7260)(2009):86-90. IF=42.351
撰写专著
1. 《再生医学——理论与技术》，科学出版社，2010年，北京
2.《新生物学年鉴2013》，科学出版社，2013年，北京
3.《生物学实验指南丛书——干细胞实验指南》，中央广播电视大学出版社，2015年，北京