基本信息
教师姓名：陈甫雪
出生年月：1970 年 5 月政治面貌：群众
所在学科：应用化学
职 称：教授，博士生导师
联系电话：010-**/**
邮 箱 ：fuxue.chen@bit.edu.cn
通讯地址：北京市海淀区中关村南大街 5 号邮 编 ：100081
教师姓名：陈甫雪
出生年月：1970 年 5 月政治面貌：群众
所在学科：应用化学
职 称：教授，博士生导师
联系电话：010-**/**
邮 箱 ：fuxue.chen@bit.edu.cn
通讯地址：北京市海淀区中关村南大街 5 号邮 编 ：100081
教育经历
2000 年 9 月—2003 年 7 月，中国科学院研究生院（成都有机化学研究所），获力学博士学位。
1992 年 9 月—1995 年 7 月，西南师范大学化学专业，获得教育学硕士学位。
1988 年 9 月—1992 年 7 月，西南师范大学化学专业，获得理学学士学位
工作经历
2008 年 5 月— 今 北京理工大学化工与环境学院，教授，博士生导师
2007 年 5 月—2008 年 4 月 北京理工大学化工与环境学院
2003 年 7 月—2007 年 4 月 四川大学化学学院，博士后
2005 年 4 月—2006 年 7 月 （日本）京都大学理学院，博士后
1995 年 8 月—2000 年 8 月，义乌市皇嘉生化有限公司，车间主任，研发部经理
研究领域
不对称催化反应研究，含能化合物合成研究
获奖情况
1. 教育部自然科学奖，一等奖（第 6 完成人），2010 年
社会兼职
教学工作
2015 年教学工作
本科生《有机合成反应工艺基础》，16 学时；
硕士研究生《手性药物技术》，32 学时；
博士研究生《手性合成》，54 学时；
2014 年教学工作
本科生《有机合成反应工艺基础》，16 学时；
硕士研究生《手性药物技术》，32 学时；
博士研究生《手性合成》，36 学时；
论文与著作
*****. Study on aeration for disengaged wet clutches using a two-phase flow model[J]. Journal of Fluids Engineering, 2010, 132: 1-6.
***,***， Chongbo Jing. Experimental research and mathematical model of drag torque in single-plate wet clutch[J]. Chinese Journal of Mechanical Engineering, 2011, 24: 91-97.
3.***, ***,***. 考虑油膜润滑作用的*****分析. ****学报 2012(19):10-16.
Yao-Feng Wang, Shaoxiang Wu, Pran Gopal Karmaker, Muhammad Sohail, Qi Wang, Fu-Xue Chen* Enantioselective Access of Trifluoromethylated Tertiary Thioether though Organocatalytic Sulfa-Michael Reaction of β-Trifluoromethyl-β,β
-Disubstituted Enones. Synthesis 2015, 47(8):1147-1153.
Yao-Feng Wang, Jiasheng Qiu, Yongtao Gao, Feipeng Lu, Pran Gopal Karmaker, Fu-Xue Chen* The Direct Electrophilic Cyanation of β-Keto Esters and Amides with Cyano Benziodoxole. Organic & Biochemical Letters 2015, 13(2):365-368.
Yao-Feng Wang, Jiashen Qiu, Dejie Kong, and Fu-Xue Chen* Ag-Mediated Radical Trifluoromethylarylation of Activated Alkenes for the Synthesis of Oxindoles Bearing CF3-Grou. Synlett 2014, 25(12), 1731-1734.
曾薇，陈甫雪, 自由基三氟甲基化反应进展. 应用化学，2014，31(6), 627-641. Chinese Journal of Applied Chemistry, 2014, 31(6):627-641.
Jiyi Guo, Yao-Feng Wang, Shaoxiang Wu, Muhammad Sohail, Qi Wang and
Fu-Xue Chen* Highly efficient Cs2CO3-catalyzed conjugate hydrocyanation of α,β
-unsaturated diesters and enones with acetone cyanohydrins. Organic Chemistry: An Indian Journal 2014, 10(7), 286-293.
Zhanda Fu, Yang Wang, Li Yang, Rui Su, Jun Chen, Fude Nie, Jinglun Huang, Fu-xue Chen* Synthesis and characteristics of novel, high-nitrogen
1,2,4-oxadiazoles (AOG and AOG2Tz). RSC Advances, 2014, 4(23), 11859-11861. 7.王阳，邱瑞，王琦，王恩雨，赵林曼，王鹏，陈甫雪*, 黄靖伦. 新型含能材料 NOG2Tz对 HMX 热分解的影响，Effects of Novel Energetic Material NOG2Tz on Thermal
Decomposition Behavior of HMX 含能材料,2014, 22(1), 22-25. Chinese Journal
Explosives & Propellants 2014, 22(1), 22-25.
Muhammad Sohail, Yao-Feng Wang, Shaoxiang Wu, Wei Zeng and Fu-Xue Chen* The Asymmetric Synthesis of Octahydrobenzofurans with three Contiguous Stereogenic Centres and Development of the Absolute Configurations. Synthetic Communications 2014, 44, 115-120.
Wei Zeng, Rui Qiu, Enyu Wang, Fu-Xue Chen* Trifluoromethyl-Promoted Oxidation of Fischer N-Heterocyclic Carbene Complexes by DMSO. (CEEE2013), Advanced Materials Research 2013, 788, 164-167.
Shaoxiang wu, Dong Pan, Chengyao Cao, Qi Wang and Fu-Xue Chen* Diastereoselective and Enantioselective Epoxidation of Acyclic β-CF3-substituted β,β-Disubstituted Enones by H2O2 with Pentafluorinated Quinidine-derived Phase Transfer Catalyst. Advanced Synthesis & Catalysis 2013, 355(10), 1917-1923.
Wei Zeng, Enyu Wang, Rui Qiu, Muhammad Sohail, Shaoxiang Wu and Fu-Xue Chen* Unprecedented Oxygen-Atom Insertion of NHC-Copper Complex: the Source of Oxygen from N,N-Dimethylformamide. Journal of Organometallic Chemistry 2013, 743, 44-48.
Muhammad Sohail, Yao-Feng Wang, Shaoxiang Wu, Wei Zeng, Jiyi Guo, Fu-Xue Chen* Marco Enantiomerically Pure Non-Superimposable Mirror Image Crystals directly by Spontaneous Resolution and Chiral Discrimination Mechanism. Chinese Chemical Letters 2013, 24(8), 695-698.
Yao-Feng Wang, Wei Zeng, Muhammad Sohail, Jiyi Guo, Shaoxiang Wu, and Fu-Xue Chen* The Highly Efficient Asymmetric Conjugate Hydrocyanation of Aromatic Enones by an Anionic Chiral Phosphate Catalys. European Journal of Organic Chemistry 2013, (21), 4624-4633.
Muhammad Sohail, Wang Yao-Feng, Wang Qi and Fu-Xue Chen*
7-Iodo-3,3-diphenyloctahydrobenzofuran. Acta Crystallographic Section E 2013, E69, o585.
Shaoxiang Wu, Jiyi Guo, Muhammad Sohail, Chengyao Cao and Fu-Xue Chen*, The enantioselective trifluoromethylation of aromatic aldehydes by quaternary ammonium bromide and (IPr)CuF at low catalyst loading. Journal of Fluorine Chemistry, 2013, 148(1), 19-29.
Fu Zhanda, Wang Yang, Li Jinshan, Chen Fu-xue* Synthesis and thermal decompostion of new energetic materials NONHT AND NONsHT 兵工学报 ACTA ARMAMENTARII 2013,34(2), 235-239.
Shaoxiang Wu, Wei Zeng, Qi Wang, Fu-Xue Chen* Asymmetric Trifluoromethylation of Aromatic Aldehydes by Cooperative Catalyst with (IPr)CuF and Quinidine-Derived Quaternary Ammonium Salt. Organic Biomolecular Chemistry 2012, 10, 9334-9337.
Fu Zhanda，Wang Yang，Chen Fu-xue* Study on the Thermal Behaviors of New Energetic Material NOG. 含能材料 Chinese J. Explosives & Propellants 2012, 20(5), 583-586.
Jinhong Song, Zhiming Zhou,* Xiao Dong, Haifeng Huang, Dan Cao, Lixuan Liang, Kai Wang, Jun Zhang, Fu-xue Chen, and Yukai Wu. Super High-Energy Materials Based on Bis(2,2-dinitroethyl)nitramine. Journal of Materials Chemistry 2012, 22(1), 3201-3209.
Zhanda Fu, Rui Su, Yang Wang, Yao-Feng Wang, Wei Zeng, Nan Xiao, Yukai Wu, Zhiming Zhou, Jun Chen, Fu-Xue Chen* Synthesis and Characterization of Energetic 3-Nitro-1,2,4-oxadiazoles. Chemistry: A European Journal 2012, 18(7), 1886-1889.
Zhanda Fu, Cheng He, Fu-xue Chen* Synthesis and Characteristics of a Novel, High-Nitrogen, Heat-Resistant, Insensitive Material (NOG2Tz). Journal Materials Chemistry 2012, 22(1), 60-63.
Jingya Yang, Shaoxiang Wu, and Fu-Xue Chen* Chiral Sodium Phosphate-Catalyzed Enantioselective 1,4-Addition of Me3SiCN to Aromatic Enones. Synlett 2010, (18), 2725-2728.
CHEN Fu-Xue*, FU Zhan-da, LIU Bao-jie, WU Yukai, ZHOU Zhi-ming. 1-氨基
-1,2,3-三唑的 VNS 反应研究. Research on the VNS Reaction of
1-Amino-1,2,3-Triazole. 兵工学报 ACTA ARMAMENTARII 2010, 31(10) 1389-1393.
Kai Wang, Zhiming Zhou*, Jinhong Song, Lixue Bi, Ning Shen, Yukai Wu, Fuxue Chen, Hongliang Wen. A metal-free aerobic oxidation of nitrotoluenes catalyzed by N,N ',N ''-trihydroxyisocyanuric acid (THICA) and a novel approach to the catalyst. Journal of Hazardous Materials 2010, 184, 400-405.
Jingya, Yang, Fu-Xue, Chen* The Highly Efficient Syntheses of β-Cyanoketones via Conjugate Addition of Me3SiCN to Aromatic Enones. Chinese Journal Chemistry 2010, 28(6), 981-987.
Jingya Yang, Yongbin Shen, and Fu-Xue Chen* Highly Efficient
Cs2CO3-Catalyzed 1,4-Addition of Me3SiCN to Enones with Water as the Additive. Synthesis 2010, (8), 1325-1333.
Wei Zeng, Jingya Yang, Bo Meng, Bo Zhang, Mingzhe Jiang and Fu-Xue Chen* ZnI2?-Catalyzed Cyanation of Acyl Chlorides with TMS-CN: An Interesting Role of Iodine. Letters of Organic Chemistry 2009, 6(8), 637-641.
Jingya Yang, Yinxian Wang, Shaoxiang Wu, and Fu-Xue Chen* The Highly Efficient 1,4-Addition of Me3SiCN to Aromatic Enones Catalyzed by CsF with Water as the Additive. Synlett 2009, (20), 3365-3367.
29.F.-X. Chen, A. Kina, T. Hayashi. “High Performance of a Chiral Diene-Rhodium Catalyst for the 1,4-Addition of Arylboroxines to α,β–Unsaturated Ketones”.
Organic Letters 2006, 8(2), 341-344.
30.F.-X. Chen, X. Feng.“Asymmetric Synthesis of Cyanohydrins ” Current Organic Synthesis 2006, 3(1), 77-97.
31.F.-X. Chen, X. Feng, “Synthesis of Racemic Tertiary Cynaohydrins” Synlett 2005, (6), 892-899 (account).
32.B. He, F.-X. Chen, Y. Li, X. Feng, G. Zhang. “Effective activation of salen/Ti(OiPr)4 catalyst with achiral phenolic N-oxides as additives for the enantioselective cyanosilylation of ketones”. European Journal of Organic Chemistry 2004, (22), 4657-4666.
33.B. He, F.-X. Chen, Y. Li, X. Feng, G. Zhang. “Achiral phenolic N-oxide as additives: An alternative strategy for enantioselective cyanosilylation of ketones”. Tetrahedron Letters 2004, 45(28), 5465-5467.
34.F.-X. Chen, X. Liu, X. Feng, B. Qin, H. Zhou, G. Zhang. “Practical cyanosilylation of ketones by double-activation catalysts”. Synthesis 2004, (14), 2266-2272.
35.F.-X. Chen, H. Zhou, B. Qin, X. Feng, B. Qin, G. Zhang, Y. Jiang. “Enantioselective Cyanosilylation of Ketones by a Catalytic Double-Activation Method Using Aluminum Complex and N-Oxide Catalysts”. Chemistry: A European Journal 2004, 10(19), 4790-4797.
36.F.-X. Chen, X. Feng, B. Qin, G. Zhang, Y. Jiang. “Enantioselective cyanosilylation of ketones catalyzed by double-activation catalysts with N-oxides”
Tetrahedron: Symposia-in-Print 2004, 60(46), 10449-10460.
37.H. Zhou, F.-X. Chen, B. Qin, X. Feng, G. Zhang. “Cyanosilylation of Ketones Catalyzed by Quaternary Ammonium Salt and N-oxide”. Synlett 2004, (6), 1077-1079.
38.F.-X. Chen, X. Feng, B. Qin, G. Zhang, Y. Jiang. “Highly Efficient Silylcyanation of Ketones by a Catalytic Double-Activation Method Using Lewis Acid and N-Oxide Catalysts”. Synlett 2003, (4), 558-560.
39.F.-X. Chen, X. Feng, B. Qin, G. Zhang, Y. Jiang, “Enantioselective Cyanosilylation of Ketones by a Catalytic Double Activation Method Employing Chiral Lewis Acid and Achiral N-Oxide Catalysts”. Organic Letters. 2003, 5(6), 949-952.
40.F.-X. Chen, X. Feng, Y. Jiang. “Asymmetric reactions catalyzed by chiral titanium complexes”. ARKIVOC 2003, (2), 21-31 (electronic: www. arkat-usa.org).
41.Z. Jiao, X. Feng, B. Liu, F.-X. Chen, G. Zhang, Y. Jiang. “Enantioselective Strecker Reaction of Aldimines and Trimethylsilyl Cyanide Promoted by Chiral N,N’
-Dioxide”. European Journal of Organic Chemistry 2003, (19), 3818-3826.
42.B. Liu, X. Feng, F.-X. Chen, G. Zhang, Y. Jiang.“Enantioselective Strecker Reaction Promoted by Chiral N-oxides”. Synlett 2001, (10), 1551-1553.
科研项目
“不对称 a-亲电氰化反应研究”，国家自然科学基金，项目负责人
新颖多氮化合物的合成方法研究”，国家自然科学基金，项目负责人
“TMS-CF3 试剂与烯酮的不对称亲核加成反应研究”，国家自然科学基金，项目负责人
“手性季铵盐参与的催化不对称 1,4-氰基加成反应研究”，国家自然科学基金，项目负责人
“有机小分子催化醛的不对称硅腈化反应研究”，国家自然科学基金，项目负责人
授权专利
1. 邻氨基磺酰基苯甲酰肼的制备方法 专利号：**3977.1
