张亮，博士，特任副研究员。2009年毕业于南开大学获信息安全专业学士学位，2014年毕业于南开大学获生物化学与分子生物学专业理学博士。随后先后在美国天主教大学和美国国立健康研究中心（NIH）从事博士后研究。2019年12月起加入中国科学技术大学生命科学学院施蕴渝院士团队，任特任副研究员。研究成果发表于Nature Communications，Nucl. Acids Res，Biochemical and Biophysical Research Communications等期刊。
研究兴趣：
线粒体核糖体的CryoET的结构研究
线粒体相关蛋白复合物，蛋白核酸复合物的功能与结构研究
代表论文（#通讯作者, *共同一作）
1.Zhang L^{*, #}, Wang H^*, Liu X, Zhou W^#, Rao Z. The crystal structure of the phosphotriesterase from M. tuberculosis,another member of phosphotriesterase-like lactonase family. Biochemical and Biophysical Research Communications.(2019). 510(2):224-229. doi: 10.1016/j.bbrc.2019.01.069.*co-first authorand corresponding author
2.Park J, Zhang L, Bang JK, Andresson T, DiMaio F, Lee KS. Phase separation of Plk4 byautoactivation and clustering drives centriole biogenesis.Nature Communications.(2019). 10(1):4959
3. Kim TS^*, Zhang L^*, Ahn J^*, Meng L, Chen Y, Lee E, Bang JK, Lim JM, Ghirlando R, Fan L, Wang Y, Kim BY, Park J, Lee KS. Molecular architecture of a cylindrical self-assembly at human centrosomes. Nature Communications. (2019). Accepted. *co-first author
4. Gao S, Zhang Land Rao VB. Exclusion of small terminase mediated DNA threading models for genome packaging in bacteriophage T4.Nucl. Acids Res.(2016). 44(9):4425-39.
5. Zhang L,Duan X, Zhou D, Dong Z, Ji K, Meng W,Li G, Li X, Yang H, Ma T and Rao Z. Structural insights into the stabilization of active, tetrameric DszC by its C‐terminus. Proteins: Structure, Function, and Bioinformatics.(2014). 82(10):2733-43.
6. Zhao C, Lou Z, Guo Y, Ma M, Chen Y, Liang S,Zhang L, Chen S, Li X, Liu Y, Bartlam M and Rao Z. Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center. J Virol.2009 Sep;83(18):9024-30
邮箱：zhangl99@ustc.edu.cn
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实验室网址：http://bionmr.ustc.edu.cn/