缪鹏
单位：中国科学院苏州生物医学工程技术研究所
地址：江苏省苏州市高新区科灵路88号
邮编：215163
电话：
个人主页： http://sourcedb.sibet.cas.cn/zw/yjdw/yjy/201602/t**_**.html
实验室介绍：


个人简历 Personal resume


缪鹏，研究员，博士生导师，英国皇家化学会会士。1986年出生于江苏南通。2011年入职中科院苏州生物医学工程技术研究所，任研究实习员，2013年晋升为助理研究员，2015年晋升为副研究员，2018年破格为研究员，2019年任博士生导师。 从事生物医学传感、DNA纳米技术等方面的研究工作，作为负责人承担国家自然科学基金面上项目/青年基金、国家重点研发计划子课题、国家重大科研装备研制项目子课题、博士后创新人才支持计划、江苏省自然科学基金、江苏省产学研合作项目、苏州市科技计划等多个项目/课题。入选全球Top 1%高被引作者(Royal Society of Chemistry)，江苏省“六大人才高峰”高层次人才，江苏省“333高层次人才培养工程”等。 截至2020年10月，已在CCS Chem., Anal. Chem.（10篇），Small, J. Mater. Chem. A ，Research等期刊发表论文140余篇（其中发表在Nature Index期刊或其他10分以上期刊的论文25篇）；出版英文专著1部；授权发明专利20件；H-index为30；多篇论文入选ESI高被引论文及期刊封面。 目前担任Chin. Chem. Lett., Sci. Rep.等期刊的编委/青年编委，担任Nat. Commun.， Adv. Mater., Adv. Funct. Mater., Chem. Sci., ACS Nano, Anal. Chem., Theranostics等多个国际著名期刊的审稿人。


研究方向 Research direction


1、生物分析化学
2、DNA纳米技术



招生信息 Enrollment information


招收化学、生物学、生物医学工程等专业背景的硕士/博士研究生。


论文专著 The monograph Researcher ID


1)DNA dumbbell and chameleon silver nanoclusters for miRNA logic operations - Research - 2020 - 2020, 2020
2)Bright carbon nanodots for miRNA diagnostics coupled with concatenated hybridization chain reaction - Chem. Commun. - 2020 - 2020, 56
3)Ratiometric fluorescence method for ctDNA analysis based on the construction of a DNA four-way junction - Analyst - 2020 - 2020, 145
4)Ultrasensitive detection of ctDNA by target-mediated in situ growth of DNA three-way junction on the electrode - ChemElectroChem - 2020 - 2020, 7
5)Fabrication of polymeric ferrocene nanoparticles for electrochemical aptasensing of protein with target catalyzed hairpin assembly - Anal. Chem. - 2019 - 2019, 91
6)Bipedal DNA walker based electrochemical genosensing strategy - Anal. Chem. - 2019 - 2019, 91
7)Polydopamine nanosphere@silver nanoclusters for fluorescent detection of multiplex tumor markers - Nanoscale - 2019 - 2019, 11
8)Silver nanoparticle@DNA tetrahedron based colorimetric detection of HIV-related DNA with cascade strand displacement amplification - J. Mater. Chem. B - 2019 - 2019, 7
9)FRET investigation toward DNA tetrahedron-based ratiometric analysis of intracellular telomerase activity - J. Mater. Chem. B - 2019 - 2019, 7
10)Carbon nanodots based fluorescent method for virus DNA analysis with isothermal strand displacement amplification - Part. Part. Syst. Charact. - 2019 - 2019, 36
11)Electrochemical detection of T4 polynucleotide kinase based on target-assisted ligation reaction coupled with silver nanoparticles - Anal. Chim. Acta - 2019 - 2019, 1085
12)Peptide cleavage-based electrochemical biosensor coupling graphene oxide and silver nanoparticles - Anal. Chim. Acta - 2019 - 2019, 1047
13)A ratiometric electrochemical assay for human 8-oxoguanine DNA glycosylase amplified by hybridization chain reaction - Electrochem. Commun. - 2019 - 2019, 103
14)Electrochemical impedance spectroscopic analysis of nucleic acids through DNA tetrahedron self-walking machine - Electrochem. Commun. - 2019 - 2019, 101
15)Star trigon structure-aided DNA walker for amplified electrochemical detection of DNA - Electrochem. Commun. - 2019 - 2019, 99
16)Preparation of a novel iron cryptate as an electrochemical probe for biosensing - Electrochem. Commun. - 2019 - 2019, 98
17)Chameleon silver nanoclusters for ratiometric sensing of miRNA - Sens. Actuators, B - 2019 - 2019, 297
18)Ratiometric electrochemical sensing strategy for the ultrasensitive detection of telomerase activity - ChemElectroChem - 2019 - 2019, 6
19)Copper (II)-ploy-L-histidine functionalized multi walled carbon nanotubes as efficient mimetic enzyme for sensitive electrochemical detection of salvianic acid A - Biosens. Bioelectron. - 2018 - 2018, 121
20)Hand-in-hand RNA nanowire-based aptasensor for the detection of theophylline - Biosens. Bioelectron. - 2018 - 2018, 101
21)DNA-functionalized porous Fe3O4 nanoparticles for the construction of self-powered miRNA biosensor with target recycling amplification - ACS Appl. Mater. Interfaces - 2018 - 2018, 10
22)Electrochemical detection of miRNA combining T7 exonuclease-assisted cascade signal amplification and DNA-templated copper - Anal. Chem. - 2018 - 2018, 90
23)Triple signal amplification strategy for ultrasensitive determination of miRNA based on duplex specific nuclease and bridge DNA-gold nanoparticles - Anal. Chem. - 2018 - 2018, 90
24)Ultrasensitive detection of DNA based on exonuclease III-assisted recycling amplification and DNAzyme motor - Bioconjug. Chem. - 2018 - 2018, 29
25)Electrochemical determination of Ca2+ based on recycling formation of highly selective DNAzyme and gold nanoparticles-mediated amplification - Bioconjug. Chem. - 2018 - 2018, 29
26)A colorimetric aptasensor for the antibiotics oxytetracycline and kanamycin based on the use of magnetic beads and gold nanoparticles - Microchim. Acta - 2018 - 2018, 185
27)Ultrasensitive electrochemical detection of miRNA based on DNA strand displacement polymerization and Ca2+-dependent DNAzyme cleavage - Analyst - 2018 - 2018, 143
28)DNA-templated copper nanoparticles for voltammetric analysis of endonuclease activity - Analyst - 2018 - 2018, 143
29)Hydrothermal synthesis of N,S co-doped carbon nanodots for highly selective detection of living cancer cells - J. Mater. Chem. B - 2018 - 2018, 6
30)A PCR-free voltammetric method for telomerase activity assay using a substrate primer on a gold electrode and DNA-triggered capture of gold nanoparticles - Microchim. Acta - 2018 - 2018, 185
31)Electrochemical detection of arsenic contamination based on hybridization chain reaction and RecJf exonuclease-mediated amplification - Chem. Eng. J. - 2018 - 2018, 353
32)Electrochemical sensing of attomolar miRNA combining cascade strand displacement polymerization and reductant-mediated amplification - Chem. Commun. - 2018 - 2018, 54
33)A novel mode of DNA assembly at electrode and its application to protein quantification - Anal. Chim. Acta - 2018 - 2018, 1029
34)An ultrasensitive aptasensor for prostate specific antigen assay based on Exonuclease T-aided cyclic cleavage - Sci. China-Chem. - 2018 - 2018, 61
35)Gold nanoparticles-based DNA logic gate for miRNA inputs analysis coupling strand displacement reaction and hybridization chain - Part. Part. Syst. Charact. - 2018 - 2018, 35
36)Colorimetric theophylline aggregation assay using an RNA aptamer and non-crosslinking gold nanoparticles - Microchim. Acta - 2018 - 2018, 185
37)A polymyxin B–silver nanoparticle colloidal system and the application of lipopolysaccharide analysis - Analyst - 2018 - 2018, 143
38)An electrochemical approach capable of prostate specific antigen assay in human serum based on exonuclease-aided target recycling - Sens. Actuators, B - 2018 - 2018, 257
39)A highly sensitive gold nanoparticle-based electrochemical aptasensor for theophylline detection - Anal. Chim. Acta - 2018 - 2018, 999
40)Proximity aptasensor for protein detection based on an enzyme-free amplification strategy - Mol. BioSyst. - 2017 - 2017, 13
41)Voltammetric determination of tumor necrosis factor-α based on the use of an aptamer and magnetic nanoparticles loaded with gold nanoparticles - Microchim. Acta - 2017 - 2017, 184
42)Hybridization chain reaction directed DNA superstructures assembly for biosensing applications - Trac-Trends Anal. Chem. - 2017 - 2017, 94
43)Exonuclease and nicking endonuclease-assisted amplified electrochemical detection of coralyne - ChemElectroChem - 2017 - 2017, 4
44)Adamantane derivatives functionalized gold nanoparticles for colorimetric detection of miRNA - Part. Part. Syst. Charact. - 2017 - 2017, 34
45)Enhanced and tunable oxygen carrier and amperometric sensor based on a glassy carbon electrode assembly of a hemoglobin-chitosan-Fe3O4 composite - Microchim. Acta - 2017 - 2017, 184
46)A quartz crystal microbalance sensor for endotoxin assay by monitoring limulus amebocyte lysate protease reaction - Anal. Chim. Acta - 2017 - 2017, 961
47)DNA modified Fe3O4@Au magnetic nanoparticles as selective probes for simultaneous detection of heavy metal ions - ACS Appl. Mater. Interfaces - 2017 - 2017, 9
48)A peptide-based electrochemical biosensor for facile measurement of whole-blood heparin - ChemElectroChem - 2017 - 2017, 4
49)TNF-α responsive DNA star trigon formation from four hairpin probes and the analytical application - Sci. China-Chem. - 2017 - 2017, 60
50)Construction of a specific binding peptide based electrochemical approach for sensitive detection of Zn2+ - J. Electroanal. Chem. - 2016 - 2016, 783
51)Isothermal amplification detection of miRNA based on catalysis of nucleases and voltammetric characteristics of silver nanoparticles - Mol. BioSyst. - 2016 - 2016, 12
52)Identification of glutathione by voltammetric analysis with rolling circle amplification - Anal. Chim. Acta - 2016 - 2016, 943
53)Highly sensitive detection of silver ions enabled by RecJf exonuclease cleavage and reductant mediated electrochemical amplification - ChemElectroChem - 2016 - 2016, 3
54)Near-infrared Ag2S quantum dots-based DNA logic gate platform for miRNA diagnostics - Anal. Chem. - 2016 - 2016, 88
55)DNA tetrahedron and star trigon nanostructures for target recycling detection of nucleic acid - Analyst - 2016 - 2016, 141
56)Peptide and carbon nanotubes assisted detection of apoptosis by square wave voltammetry - Electrochim. Acta - 2016 - 2016, 199
57)Nuclease assisted target recycling and spherical nucleic acids gold nanoparticles recruitment for ultrasensitive detection of microRNA - Electrochim. Acta - 2016 - 2016, 190
58)Apoptosis evaluation by electrochemical techniques - Chem.-Asian J. - 2016 - 2016, 11
59)MicroRNA detection based on analyte triggered nanoparticle localization on a tetrahedral DNA modified electrode followed by hybridization chain reaction dual amplification - Chem. Commun. - 2015 - 2015, 51
60)Identification of cellular microRNA coupling strand displacement polymerization and nicking-endonuclease-based cleavage - ChemPlusChem - 2015 - 2015, 80
61)Study of autocatalytic oxidation reaction of silver nanoparticles and the application for nonenzymatic H2O2 assay - Chem. Phys. Lett. - 2015 - 2015, 635
62)Facile synthesis of carbon nanodots from ethanol and their application in ferric (III) ion assay - J. Mater. Chem. A - 2015 - 2015, 3
63)An elastography analytical method for rapid detection of endotoxin - Analyst - 2015 - 2015, 140
64)Tetrahedral DNA nanostructure-based microRNA biosensor coupled with catalytic recycling of the analyte - ACS Appl. Mater. Interfaces - 2015 - 2015, 7
65)Ultrasensitive detection of microRNA through rolling circle amplification on a DNA tetrahedron decorated electrode - Bioconjug. Chem. - 2015 - 2015, 26
66)Electrochemical tracking hydrogen peroxide secretion in live cells based on autocatalytic oxidation reaction of silver nanoparticles - Electrochem. Commun. - 2015 - 2015, 53
67)Signal amplification by enzymatic tools for nucleic acids - Trac-Trends Anal. Chem. - 2015 - 2015, 67
68)Recent advances in carbon nanodots: synthesis, properties and biomedical applications - Nanoscale - 2015 - 2015, 7
69)Highly sensitive microRNA quantification with zero background signal from silver nanoparticles - Electrochem. Commun. - 2015 - 2015, 51
70)Ultrasensitive electrochemical detection of microRNA with star trigon structure and endonuclease mediated signal amplification - Biosens. Bioelectron. - 2015 - 2015, 63
71)An aptasensor for detection of potassium ions based on RecJf exonuclease mediated signal amplification - Analyst - 2014 - 2014, 139
72)Electrochemical impedance spectroscopy study of proteolysis using unmodified gold nanoparticles - Electrochem. Commun. - 2014 - 2014, 47
73)Peptide-based electrochemical approach for apoptosis evaluation - Biosens. Bioelectron. - 2014 - 2014, 62
74)Gold nanoparticles and cleavage-based dual signal amplification for ultrasensitive detection of silver ions - Anal. Chem. - 2013 - 2013, 85