首页>师资队伍>教授
徐晓嵘
教授/博士生导师　联系地址:合肥市金寨路96号中国科大精密机械与精密仪器系.邮编：230026电话：**.电子邮箱：xux@ustc.edu.cn团队网页：www.mbit.ustc.edu.cn　　　徐教授于1992年本科毕业于中国科技大学精密机械与仪器系，1995年获美国纽约州立大学石溪分校机械系硕士学位，1999年获美国麻省理工学院机械工程系博士学位，2000年至于2004年任美国硅谷一家医疗器械公司的技术开发部主管，2004年底任美国俄亥俄州立大学生物医学工程系助理教授，2011年任美国俄亥俄州立大学生物医学工程系副教授，2012年任中国科学技术大学精密机械与精密仪器系教授。　徐教授的科研方向主要集中在医疗仪器研发，多模式生物医学影像，以及影像导航治疗。他的实验室已经设计并且测试了多个便携式多模式医疗影像系统，研制了多种多功能可降解的微纳造影剂，开发了多种影像、治疗和药物传输释放技术，完成了四项临床试验，并发表了十一项美国及国际专利。目前开展的课题包括宫颈病变的超广谱影像、慢性伤口的多模态影像与治疗、便携式手术导航、乳腺动态弹性影像、微纳米药物包裹技术、载药多功能微泡、生物光学仿体的三维打印、以及医疗光学影像仪器的标准化。2010年徐教授被评为十大最优秀的美国俄亥俄人物以及两个科研明星之一。2011年他被美国俄亥俄州授予该年度唯一的TechColumbus发明家奖。2012年他被评为“百人计划”教授。　近期相关论文：1.　Cao,Y.,R.X.Xu,andZ.Liu,Ahigh-throughputquantificationmethodofcurcuminoidsandcurcuminmetabolitesinhumanplasmaviahigh-performanceliquidchromatography/tandemmassspectrometry.JChromatogrBAnalytTechnolBiomedLifeSci,2014.949-950:p.70-8.2.　Pu,C.,S.Chang,J.Sun,S.Zhu,H.Liu,Y.Zhu,Z.Wang,andR.X.Xu."Ultrasound-MediatedDestructionofLhrha-TargetedandPaclitaxel-LoadedLipidMicrobubblesfortheTreatmentofIntraperitonealOvarianCancerXenografts."MolPharm11,no.1(Jan62014):49-58.(Impactfactor:4.388)3.　Liu,H.,S.Chang,J.Sun,S.Zhu,C.Pu,Y.Zhu,Z.Wang,andR.X.Xu."Ultrasound-MediatedDestructionofLhrha-TargetedandPaclitaxel-LoadedLipidMicrobubblesInducesProliferationInhibitionandApoptosisinOvarianCancerCells."MolPharm11,no.1(Jan62014):40-8.(Impactfactor:4.388).4.　Si,T.,L.Zhang,G.Li,C.J.Roberts,X.Yin,andR.Xu."ExperimentalDesignandInstabilityAnalysisofCoaxialElectrosprayProcessforMicroencapsulationofDrugsandImagingAgents."JBiomedOpt18,no.7(Jul2013):075003.(Impactfactor:3.371)5.　L.Zhang,J.Huang,T.Si,andR.X.Xu*,"Co-axialelectrosprayofmicroparticlesandnanoparticlesforbiomedicalapplications,"ExpertReviewofMedicalDevices,9(6):595-612(2012).(Impactfactor:2.052)6.　S.Chang,J.Guo,J.Sun,S.Zhu,Y.Yan,Y.Zhu,M.Li,Z.Wang,andR.X.Xu*,"Targetedmicrobubblesforultrasoundmediatedgenetransfectionandapoptosisinductioninovariancancercells,"UltrasonSonochem,vol.20,pp.171-9(2013).(Impactfactor:3.567)7.　K.Mitra,J.Melvin,S.Chang,K.Park,A.Yilmaz,S.Melvin,andR.X.Xu*,"IndocyanineGreenloadedmicroballoonsforbiliaryimagingincholecystectomy,"JournalofBiomedicalOptics,17(11):116025(2012).(Impactfactor:3.371)8.　R.X.Xu*,D.W.Allen,J.Huang,S.Gnyawali,J.Melvin,H.Elgharably,G.Gordillo,K.Huang,V.Bergdall,M.Litorja,J.P.Rice,J.Hwang,andC.K.Sen,"Developingdigitaltissuephantomsforhyperspectralimagingofischemicwounds,"BiomedOptExpress,vol.3,pp.1433-45(2012).9.　RonaldXu*,"Multifunctionalmicrobubblesandnanobubblesforphotoacousticimaging,"ContrastMediaMolImaging6:401-411(2011).(Impactfactor:3.392,invitedpaper)10.RonaldXu*,JeffXu,TaoZuo,RulongShen,TimHuang,andMichaelTweedle.Drug-loadedbiodegradablemicrospheresforimage-guidedcombinatoryepigenetictherapy.JournalofBiomedicalOptics.Vol.16,no.2:020507(2011).(Impactfactor:3.371)11.ChulhongKim,RuoguQin,JeffXu,LihongWang*,andRonaldXu*.Ultrasoundandphotoacousticdual-modalimagingofthickbiologicaltissuewithmicrobubbleenhancement.JournalofBiomedicalOptics.Vol.15,no.1:010510(2010).(Impactfactor:3.371)12.HamidEl-Dahdah,BeiWang,GuanglongHe,RonaldX.Xu*.AnAutomaticOcclusionDeviceforRemoteControlofTumorTissueIschemia.TechnologyinCancerResearchandTreatment.Vol.1,no.9:71-76(2010).(Impactfactor:2.627)13.JeffXu,JiweiHuang,RuoguQin,StephenPovoski,EdwardMartin,RonaldXu*.Synthesizingandbindingdual-modepoly(lactic-co-glycolicacid)(PLGA)nanobubblesforcancertargetingandimaging.Biomaterials.Vol.7,no.31:1716-1722(2010).(Impactfactor:7.325)14.JiweiHuang,JeffS.Xu,RonaldX.Xu*.Heat-sensitivemicrobubblesforintraoperativeassessmentofcancerablationmargins.Biomaterials.Vol.6,no.31:1278-1286(2010).(Impactfactor:7.325)15.LeileiZhang,JeffS.Xu,VirginiaM.Sanders,AlanD.Letson,CynthiaJ.Roberts,andRonaldX.Xu*,Multifunctionalmicrobubblesforimage-guidedantivascularendothelialgrowthfactortherapy,JournalofBiomedicalOptics.Vol.15,no.3,p030515.(2010).(Impactfactor:3.371)16.PengZou,StephenP.Povoski,*,NathanC.Hall,MichelleM.Carlton,GeorgeH.Hinkle,RonaldX.Xu,CathyM.Mojzisik,MorganA.Johnson,MichaelV.Knopp,EdwardW.Martin,andDuxinSun.2010.124I-HuCC49deltaCH2forTAG-72antigen-directedpositronemissiontomography(PET)imagingofLS174Tcolonadenocarcinomatumorimplantsinxenograftmice:Preliminaryresults.WorldJournalofSurgicalOncology.Vol8,p65(2010).17.RonaldX.Xu,KunHuang,RuoguQin,JiweiHuang,JeffS.Xu,LiyaDing,UrmilaS.Gnyawali,GayleGordillo,SuryaC.Gnyawali,andChandanK.Sen*.Dual-modeimagingofcutaneoustissueoxygenationandtissuevascularthermalreactivity.JournalofVisualizedExperiments.doi:10.3791/2095(2010).18.RonaldXu*,StephenPovoski,EdwardMartin.Targeteddeliveryofmicrobubblesandnanobubblesforimage-guidedthermalablationtherapyoftumors.ExpertRevMedDevices.7(3):p303-6.(2010).(Impactfactor:2.052)19.PengZou,SongboXu,StephenP.Povoski,AnnaWang,MorganA.Johnson,EdwardW.Martin,Jr.,VishSubramaniam,RonaldXu*,andDuxinSun*.Near-InfraredFluo-rescenceLabeledAnti-TAG-72MonoclonalAntibodiesforTumorImaginginColorectalCancerXenograftMice.MolecularPharmaceutics.Vol.6,no.2:428-440.(2009).(Impactfactor:4.388)20.RonaldXu*,JiweiHuang,JeffXu,DuxinSun,GeorgeHinkle,EdwardMartinandS.Povoski.Fabricationofindocyaninegreenencapsulatedbiodegradablemicro－bubblesforstructuralandfunctionalimagingofcancer.JournalofBiomedicalOptics.Vol.14,no.3:034020(2009).(Impactfactor:3.371)21.StephenP.Povoski*,RafaelE.Jimenez,WenleP.Wang,RonaldX.Xu.Standardizedandreproduciblemethodologyforthecomprehensiveandsystematicassessmentofsurgicalresectionmarginsduringbreast-conservingsurgeryforinvasivebreastcancer.BMCCancer.Vol.9,no.1:254.(2009).(Impactfactor:3.159)