姓名：张欣
地址：科学岛
类型：博导
所在科研单元：强磁场中心


导师介绍



张欣，中国科学院强磁场科学中心研究员，博士生导师。2001年毕业于北京大学医学部，获得学士学位；2007年毕业于美国印第安纳大学 Bloomington分校，获得博士学位。2008-2012年在哈佛医学院/Dana-Farber癌症研究所做博士后。2012年回国加入中国科学院强磁场科学中心，成立强磁生物学课题组，参与中国科学院科技创新与交叉合作团队。任课题组长以来，以通讯作者身份在 eLife和Nano Research等杂志发表论文30余篇。受邀主编磁场与生命科学 交叉领域中英文专著共三部(Springer 2017；科学出版社2018a,b)，主编 了“强磁场与生命健康”香山会议专辑，组织“第八届国际磁科学会 议”等，推动了磁场与生物医学交叉领域的发展，产生了显著的国际影 响力。张欣研究员领导的实验室依托强磁场大科学装置率先建立起国际 上首个≥20 T强磁场生物学研究平台，并开发了溶液扫描隧道显微镜技 术的生物学应用；借助强磁场平台与技术揭示了磁场抑制肿瘤细胞分裂 和增殖的重要分子机制，并开发了其在抗肿瘤和外科手术中的应用，合作“磁外科”项目获“中华医学科技奖一等奖”。

Introduction



Dr. Xin Zhang, the group leader, graduated in 2001 from Beijing University Health Science Center with a Bachelor of Medicine degree. She obtained her PhD degree in 2007 studying mitosis and its regulation by mitotic kinesins and Aurora kinases at Indiana University, Bloomington, under the direction of Prof. Claire Walczak. In 2008, she started postdoctoral research in Ulrike Eggert’s lab at Harvard Medical School and Dana-Farber Cancer Institute in the area of chemical biology, biochemistry and cell biology. In 2012, she moved back to China as a principal investigator at the Chinese Academy of Sciences, High Magnetic Field Laboratory, Hefei. The lab is mainly interested in cellular responses, molecular mechanisms and potential biomedical applications of moderate to high static magnetic fields, as well as low frequency magnetic fields. The lab is also interested in the interplay between membrane trafficking and cell division.

研究领域



物质科学与生命科学交叉领域，重点研究强磁场生物安全性和磁场的生物医学应用及其机制。

招生专业



博士招生计划：          1、专业：生物物理学招生方向：磁场生物效应学术硕士招生计划：          1、专业：生物物理学（硕士）招生方向：磁场生物效应专业学位硕士招生计划：          1、专业：生物与医药（专硕）招生方向：磁场生物效应工程博士招生计划：          1、专业：材料与化工招生方向：材料与化工博士招生计划：          1、专业：凝聚态物理招生方向：软凝聚态物理          2、专业：生物物理学招生方向：磁场生物效应学术硕士招生计划：          1、专业：凝聚态物理（硕士）招生方向：软凝聚态物理          2、专业：生物物理学（硕士）招生方向：磁场生物效应专业学位硕士招生计划：          1、专业：生物与医药（专硕）招生方向：磁场生物效应          2、专业：生物与医药（专硕）招生方向：物理生物与技术博士招生计划：          1、专业：生物物理学招生方向：磁场生物效应          2、专业：生物物理学招生方向：肿瘤生物学学术硕士招生计划：          1、专业：生物物理学（硕士）招生方向：磁场生物效应          2、专业：生物物理学（硕士）招生方向：肿瘤生物学专业学位硕士招生计划：          1、专业：生物与医药（专硕）招生方向：磁场生物效应          2、专业：生物与医药（专硕）招生方向：肿瘤生物学

研究成果



1. 张欣*，Kevin Yarema，许安著。张磊，刘娟娟译。稳态磁场的生物学效应。科学出版社. 2018. ISBN：978-703-056598-3.
2. Xin Zhang*, Kevin Yarema, An Xu. Biological effects of static magnetic fields. Springer. 2017. ISBN: 978-981-10-3579-1.
3. Xin Zhang* and Junfeng Wang. Interdisciplinary Research of Magnetic Fields and Life Sciences. Science Press. 2018. ISBN：978-7-03-059910-0
4. Huizhen Wang and Xin Zhang*. ROS Reduction does not Decrease the Anti-cancer Efficacy of X-ray in Two Breast Cancer Cell lines. Oxidative Medicine and Cellular Longevity. 2019. 1-12.
5. Lei Zhang#, Yubin Hou #, Zhiyuan Li, Xinmiao Ji, Ze Wang, Huizhen Wang, Xiaofei Tian, Fazhi Yu, Zhenye Yang, Li Pi, Timothy Mitchison*, Qingyou Lu*, Xin Zhang*. 27 T Ultra-high Static Magnetic Field Changes Orientation and Morphology of Mitotic Spindles in Human Cells. eLife. 2017. 6: e22911
6. Jihao Wang#, Lei Zhang#, Chen Hu, Qingsong Liu, Yubin Hou, Xin Zhang*, Qingyou Lu*. Sub-molecular features of single proteins resolved in solution using scanning tunneling microscopy. Nano Research. 2016. 9 (9):2511-2560
7. Xiaofei Tian#, Dongmei Wang#, Shuang Feng, Lei Zhang, Xinmiao Ji, Ze Wang, Qingyou Lu, Chuanying Xi, Li Pi, Xin Zhang*. Effects of 3.5–23.0?T static magnetic fields on mice: A safety study. Neuroimage. 2019. 199. 273-280.
8. Yan Luo#, Xinmiao Ji#, Juanjuan Liu, Zhiyuan Li, Wenchao Wang, Wei Chen, Junfeng Wang, Qingsong Liu, Xin Zhang*. 2016. Moderate intensity static magnetic fields affect mitotic spindles and increase the antitumor efficacy of 5-FU and Taxol. Bioelectrochemistry. 109: 31-40.
9. Lei Zhang, Xingxing Yang, Juanjuan Liu, Yan Luo, Zhiyuan Li, Xinmiao Ji, Wenchao Wang, Xin Zhang*. 1T moderate intensity static magnetic field affects Akt/mTOR pathway and increases the antitumor efficacy of mTOR inhibitors in CNE-2Z cells. Science Bulletin. 2015. 60(24): 2120.
10. Xin Zhang, Wenchao Wang, Anne Bedigian, Margaret Coughlin, Tim Mitchison and Ulrike S. Eggert. Dopamine receptor DRD3 regulates endocytic sorting by a Prazosin-sensitive interaction with COPI. PNAS. 2012. 109(31):12485-90.