李增，男，1985年4月出生，副教授，博士，硕士研究生导师，主要研究方向为靶向性药物分子设计、合成及活性研究、药物分子作用机制研究、天然活性成分的结构改造与构效关系研究等。中国药学会、中国药理学会会员。主要承担本科生《药物化学》、《波谱解析》、《波有机化学》等课程的教学工作。主持国家自然科学基金、中国博士后科学基金项目、安徽省自然科学基金、安徽医科大学博士启动基金各1项，以主要参与人参加了多项国家自然科学基金、安徽省科技厅科技攻关项目等研究。以第一作者或合作作者发表论文20余篇。
邮箱：lizeng@ahmu.edu.cn

科研项目
1)国家自然科学基金青年科学基金项目，项目编号，**；时间，201401-201612，主持
2)安徽省自然科学基金青年基金项目，项目编号，**QC53 ；时间，201307-201506，主持
3)中国博士后科学基金项目，项目编号，2015M571916, 主持
在国内外刊物上发表的主要学术论文
1) Liu Chen, Mu Chaoyu, Li Zeng*, Xu Liang.Imazamethabenz inhibits human breast cancer cell proliferation, migration and invasion via combination with Pin1. Mol Med Rep. 2017, 15(5):3210-3214.. (通讯作者)
2) Li Zeng, Liu Chen, Huang Cheng, MengXiaoming, Zhang Lei, He Jinhui, Li Jun. Quinazoline derivative QPB-15e stabilizes the c-myc promoter G-quadruplex and inhibits tumor growth in vivo. Oncotarget. 2016, 7(23):34266-34276.
3) He YH,Li Z, Ni MM, Zhang XY, Li MF, Meng XM, Huang C, Li J. Cryptolepine derivative-6h inhibits liver fibrosis in TGF-β1-induced HSC-T6 cells by targeting the Shh pathway. Can J PhysiolPharmacol. 2016, 94(9):987-995. (共同一作)
4) Zeng Li, Bin Wang, Liang Tang, Jun Li*. Quinazoline derivative compound (11d) as a novel angiogenesis inhibitor inhibiting VEGFR2 and blocking VEGFR2-mediated Akt/mTOR /p70s6k signaling pathway. Iran J Basic Med Sci. 2016, 19(4): 411-416.
5) 李增, 陈灵芝, 刘晨. 枸橘苷抑制血管生成作用的研究. 时珍国医国药, 时珍国医国药. 2016, 2: 277-279.
6) Zeng Li*, Chaoyu Mu, Bin Wang and Juan Jin. Graveoline analogs exhibiting selective acetylcholinesterase inhibitory activity as potential lead compounds for the treatment of Alzheimer’s disease. Molecules. 2016, 21: pii: E132.
7) Chaoyu Mu, Anyong Wang, Chen Chen, Zeng Li*, Yuanhong Xu.Three-step method for the amplification of the coxsackievirus A10 genome.Genetics and Molecular Research. 2016, 15:1-8. (通讯作者)
8) Chaoyu Mu, Anyong Wang, Chen Chen, Lei Zhao, Zeng Li*.A real-time RT-PCR assay for rapid detection of Coxsackievirus A10.Genetics and Molecular Research. 2015, 14: 17496-17504.(通讯作者)
9) Guangjin Yu, Zeng Li, , Liang Tang, QiruXiong. Synthesis and evaluation of 2,4-disubstituted quinazoline derivatives with potent anti-angiogenesis activities. Molecules. 2014, 19, 8916-8932. (共同一作)
10) Zeng Li, Bin Wang, Jin-QiangHou, Shi-Liang Huang, Tian-Miao Ou, Jia-Heng Tan, Lin-Kun An, Ding Li, Lian-QuanGu, Zhi-Shu Huang. 2-(2-Indolyl-)-4(3H)-QuinazolinesDerivates as New Inhibitors of AChE: Design, Synthesis, Biological Evaluation and molecular modeling. Journal of Enzyme Inhibition and Medicinal Chemistry. 2013, 28, 583-592.
11) Zeng Li, Jia-Heng Tan, Jin-Hui He, Tian-Miao Ou,Yi Long, Ding Li, Lian-QuanGu, Zhi-Shu Huang. Disubstitutedquinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.European Journal of Medicinal Chemistry. 2012, 47, 299-311.
12) Jun Zhao, Zeng Li, Mingli Wang, Zhaoxuan Zhang, Houyun Ma, Jun Chang, DongmeiGao, Shiping Wang. Manipulation of autophagy by HCMV infection is involved in mTOR and influences the replication of virus. ActaBiochimBiophys Sin. 2013, 45, 979-981. (共同一作)
13) Bing Wang , Zeng Li, Xiao-Ning Wang, Jia-Heng Tan, Lian-QuanGu, Zhi-Shu Huang. A new approach to the facile synthesis of 2-substituted-quinazolin-4(3H)-ones.Chinese Chemical Letters. 2011, 22, 951–953. (共同一作)