1.简介
高蓝，男，理学博士，校聘副教授，硕士研究生导师。2017年至今在安徽医科大学公共卫生学院卫生毒理学系工作，研究方向主要为发育和生殖毒理学。现任中华预防医学会自由基预防医学专委会青年委员、中华预防医学会环境卫生分会青年委员、安徽省预防医学会卫生毒理专委会委员、中国毒理学会会员。目前主持国家自然科学基金青年基金、安徽省自然科学基金青年项目、安徽省高等学校自然科学研究项目重点项目、安徽医科大学基础与临床合作研究提升计划、安徽医科大学博士科研资助基金、安徽医科大学校科研基金各1项，参与国自然重大项目、面上项目多项。指导本科生国家级“大学生创新训练计划”1项。曾获安徽省教学成果三等奖、安徽医科大学“优秀教师”、安徽医科大学公共卫生学院“先进个人”、安徽医科大学公共卫生学院课程思政竞赛一等奖、安徽医科大学公共卫生学院青年教师教学基本功竞赛三等奖。
2.教育经历
2012/09-2016/12，中科院昆明植物研究所植物化学与西部植物资源持续利用
国家重点实验室，药物化学，博士
2013/12-2015/10，中科院长春应化所电分析化学国家重点实验室，客座
2009/09-2012/06，南京农业大学与中科院昆明动物所联培，动物学，硕士
2004/09-2008/06，安徽农业大学，生物科学，学士
3.发表论文
1)Li J^#, Gao L^#(高蓝), Zhu BB, Lin ZJ, Chen J, Lu X, Wang H, Zhang C, Chen YH, Xu DX. Long-term 1-nitropyrene exposure induces endoplasmic reticulum stress and inhibits steroidogenesis in mice testes.Chemosphere, 2020; 251:126336. (^#并列第一作者)
2)Gao L(高蓝)，Chen J，Gao J，Wang HD^*，Xiong WY^*. Super-resolution microscopy reveals the reorganization of GLUT4 on plasma membrane regulated by insulin resistance. Journal of cell science, 2017; 130 (2): 396-405 (^*共同通讯作者)
3)Zhang ZY^#，Gao L^#(高蓝)，Shen CB，Rong MQ, Yan XW，Lai R. A potent anti-thrombosis peptide (vasotab TY) from horsefly salivary glands，International Journal of Biochemistry & Cell Biology, 2014; 54: 83–88. (^#并列第一作者)
4)Kong QH^#，Gao L^#(高蓝)，Niu YF，Gongpan PC，Li Y^*，Xiong WY^*. RACK1 is required for adipogenesis，American Journal of Physiology-Cell Physiology, 2016; 311(5): C831. (^#并列第一作者) (^*共同通讯作者)
5)Xiong YW^#, Xu XF^#, Zhu HL^#, Cao XL, Yi SJ, Shi XT, Zhu KH, Nan Y, Zhao LL, Zhang C, Gao L(高蓝), Chen YH, Xu DX^*, Wang H^*. Environmental exposure to cadmium impairs fetal growth and placental angiogenesis via GCN-2-mediated mitochondrial stress.J Hazard Mater, 2020; 401:123438. (^#并列第一作者) (^*共同通讯作者)
6)Shi XT^#, Zhu HL^#, Xiong YW, Liu WB, Zhou GX, Cao XL, Yi SJ, Dai LM, Zhang C, Gao L(高蓝), Xu DX, Wang H. Cadmium down-regulates 11β-HSD2 expression and elevates active glucocorticoid level via PERK/p-eIF2α pathway in placental trophoblasts. Chemosphere, 2020; 254:126785. (^#并列第一作者)
7)Wang B^#, Xu S^#, Lu X, Ma L, Gao L(高蓝), Zhang SY, Li R, Fu L, Wang H, Sun GP, Xu DX. Reactive oxygen species-mediated cellular genotoxic stress is involved in 1-nitropyrene-induced trophoblast cycle arrest and fetal growth restriction. Environ Pollut, 2020; 260:113984. (^#并列第一作者)
8)Lu X^#, Tan ZX^#, Wang B, Li J, Hu B, Gao L(高蓝), Zhao H, Wang H, Chen YH^*, Xu DX^*. Maternal 1-nitropyrene exposure during pregnancy increases susceptibility of allergic asthma in adolescent offspring. Chemosphere, 2020; 243:125356. (^#并列第一作者) (^*共同通讯作者)
9)Xiong YW^#, Zhu HL^#, Nan Y, Cao XL, Shi XT, Yi SJ, Feng YJ, Zhang C, Gao L(高蓝), Chen YH, Xu DX^*, Wang H^*. Maternal cadmium exposure during late pregnancy causes fetal growth restriction via inhibiting placental progesterone synthesis. Ecotoxicol Environ Saf, 2020; 187:109879. (^#并列第一作者) (^*共同通讯作者)
10)Nan Y^#, Yi SJ^#, Zhu HL, Xiong YW, Shi XT, Cao XL, Zhang C, Gao L(高蓝), Zhao LL, Zhang J, Xu DX^*, Wang H^*. Paternal cadmium exposure increases the susceptibility to diet-induced testicular injury and spermatogenic disorders in mouse offspring. Chemosphere, 2019; 246:125776. (^#并列第一作者) (^*共同通讯作者)
11)Zhu HL^#, Xu XF^#, Shi XT, Feng YJ, Xiong YW, Nan Y, Zhang C, Gao L(高蓝), Chen YH, Xu DX, Wang H. Activation of autophagy inhibits cadmium-triggered apoptosis in human placental trophoblasts and mouse placenta. Environ Pollut, 2019; 254:112991. (^#并列第一作者)
12)Chen W, Gao XX, Ma L, Liu ZB, Li L, Wang H, Gao L(高蓝), Xu DX^*, Chen YH^*. Obeticholic Acid Protects against Gestational Cholestasis-Induced Fetal Intrauterine Growth Restriction in Mice. Oxid Med Cell Longev, 2019; 2019:**.(^*共同通讯作者)
13)Xu S, Song J, Zhang ZH, Fu L, Gao L(高蓝), Xie DD, Yu DX, Xu DX^*, Sun GP^*. The Vitamin D status is associated with serum C-reactive protein and adhesion molecules in patients with renal cell carcinoma. Sci Rep, 2019; 9(1):16719. (^*共同通讯作者)
14)Song J^#, Xu S^#, Zhang ZH, Chen YH, Gao L(高蓝), Xie DD, Sun GP, Yu DX^*, Xu DX^*. The correlation between low vitamin D status and renal interleukin-6/STAT3 hyper-activation in patients with clear cell renal cell carcinoma. Steroids, 2019; 150:108445. (^#并列第一作者) (^*共同通讯作者)
15)Song YP^#, Chen YH^#, Gao L(高蓝), Wang P, Wang XL, Luo B, Li J, Xu DX. Differential effects of high-fat diets before pregnancy and/or during pregnancy on fetal growth development. Life Sci, 2018; 212:241-250. (^#并列第一作者)
16)Chen JL，Liu TZ，Gao J，Gao L(高蓝)，Zhou LL，Cai MJ，Shi Y，Jiang JG，Tong T^*，Wang HD^*. Variation in carbohydrates between cancer and normal cell membranes revealed by super-resolution fluorescence imaging，Advanced Science, 2016; 3(12) (^*共同通讯作者)