张继坦 博士，硕士生导师
办公室：花津校区理科实训大楼A楼1115
实验室：花津校区理科实训大楼A楼1127、1126
联系方式：zhangjt@ahnu.edu.cn

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教育经历

2005年9月-2009年7月 安徽师范大学 理学学士 （导师：谢美华教授）


2009年9月-2012年7月 安徽师范大学 理学硕士 （导师：谢美华教授）
2012年9月-2016年3月 浙江大学 理学博士 （导师：张玉红教授）

工作经历
2016年7月-2017年7月 中山大学 特聘副研究员
2017年8月-至今 安徽师范大学

经费项目
“基于钴催化碳氢键活化的手性氨基酸衍生物的合成反应研究”，中央高校基本科研业务费中山大学青年教师培育项目(31)，2017年01月-2017年12月，项目负责人。
“廉价金属催化的基于碳氢键活化的不对称串联反应”，国家自然科学基金青年项目(**)，2018年01月-2020年12月，项目负责人。
安徽师范大学博士科研启动基金，2018年01月-2020年12月，项目负责人。

研究领域




过渡金属催化惰性键断裂
不对称催化
有机合成方法学

课题组
诚挚欢迎每一位对我们课题感兴趣的同学加盟，并欢迎大家随时来参观我们的实验室！
课题组成员




本科生：创新团队（2016级化学）-周兰、刘楠楠、朱丽
毕业设计（2016级）-周兰、朱金瑶、任豪、孙博文
创新实验 居虎（2017级英才班）、丁珂（2017级英才班）、张玥（2018级英才班）、周开元（2018级英才班）
硕士生：


吴满意，2016级 有机 徐俏俏，2017级 应化 李莉，2018级 有机 孙朋朋，2018级 有机

赵婉慧，2019级 有机王玉芳，2019级 有机吴叶荷，2020级 有机


杨海涛，2020级 有机




代表性论文



19) Access to C2 C-H olefination, alkylation and deuteration of indoles by rhodium(III) catalysis: An entry for diverse synthesis, Jiaping Wu,^* Baiyang Qian, Haitao Yang, Lili Lu, Yongjia Shang,* Jitan Zhang, Org. Chem. Front. 2021, DOI: 10.1039/D1QO00133G.

18) Expeditious synthesis of phenanthridines through a Pd/MnO₂-mediated C–H arylation/oxidative annulation cascade from aldehydes, aryl iodides and amino acids, Jian Fan, Li Li,Jitan Zhang*, Meihua Xie*, Chem. Commun. 2020, DOI: 10.1039/d0cc00300j.



17) Acid-Controlled Access to β?Sulfenyl Ketones and α,β-Disulfonyl Ketones by Pummerer Reaction of β?Keto Sulfones and Sulfoxides, Jian Fan, Yiming Zhao, Jitan Zhang, Meihua Xie*,Yuzhong Zhang*, J. Org. Chem. 2020, 85, 691.



16) Construction of N?C Axial Chirality through Atroposelective C?H Olefination of N?Arylindoles by Palladium/Amino Acid Cooperative Catalysis, Jitan Zhang，*Qiaoqiao Xu, Jiaping Wu, Jian Fan, Meihua Xie*, Org. Lett. 2019, 21, 6361. (Highlighted by Synfacts, 2019, 15, 1156)

15) Metal-free cascade rearrangement/radical addition/oxidative C–H annulation of propargyl alcohols with sodium sulfinates: access to 2-sulfenylindenones, Changqing Liu,Bo Wang,Ziyi Guo, Jitan Zhang, Meihua Xie*, Org. Chem. Front. 2019, 6, 2796.



14) Selective C–H acylation of indoles with a-oxocarboxylic acids at the C4 position by palladium catalysis,Jitan Zhang，* Manyi Wu, Jian Fan, Qiaoqiao Xu, Meihua Xie,*Chem. Commun.2019, DOI: 10.1039/c9cc03893k.




13) NH₄I-promoted N-acylation of amines via the transamidation of DMF and DMA under metal-free conditions, Jiahui Chen, Jin Jia, Ziyi Guo, Jitan Zhang,* Meihua Xie*, Tetrahedron Lett. 2019, 60, 1426.



12) Synthesis of 2-Acetyl Trisubstituted Furans via Copper-Mediated Deacylation Cleavage of Unstrained C(sp³)-(sp²) Bonds, Jian Fan, Shengke Wang, Jiahui Chen, Manyi Wu,Jitan Zhang,* Meihua Xie*, Org. Chem. Front.2019, 6, 437.





11) Metal-Free Functionalized Tetrasubstituted Alkenes by Three-Component Reaction of Alkynes, Iodine, and Sodium Sulfinates,Jitan Zhang,* Zhenda Liang, Jun Wang, Ziyi Guo, Changqing Liu, Meihua Xie,* ACS Omega 2018, 3, 18002.





10) Enantioselective Synthesis of C–N Axially ChiralN-Aryloxindoles by Asymmetric Rhodium-Catalyzed Dual C-H Activation, Honghe Li,^# Xiaoqiang Yan,^#Jitan Zhang, Weicong Guo, Jijun Jiang, and Jun Wang,*Angew. Chem. Int. Ed.2019, DOI: 10.1002/anie..


9) Copper(II)/Silver(I)-Catalyzed Sequential Alkynylation and Annulation of Aliphatic Amides with Alkynyl Carboxylic Acids: Efficient Synthesis of Pyrrolidones, Jitan Zhang, Danyang Li, Hui Chen, Binjie Wang, Zhanxiang Liu, Yuhong Zhang,* Adv. Synth. & Catal. 2016, 358, 792.


8) An Approach to Five-Membered Lactams from Aliphatic Amides and Terminal Acetylenes by Nickel Catalysis, Cong Lin, Jitan Zhang, Zhengkai Chen, Yue Liu, Zhanxiang Liu, Yuhong Zhang,* Adv. Synth. & Catal. 2016, 358, 1778.


7) Cobalt-Catalyzed Cyclization of Aliphatic Amides and Terminal Alkynes with Silver Cocatalyst,Jitan Zhang, Hui Chen, Cong Lin, Zhanxiang Liu, Chen Wang, Yuhong Zhang,*J. Am. Chem. Soc.2015, 137, 12990.


6) Copper-Mediated Aryloxylation and Vinyloxylation of β-(sp³)-H Bond of Propionamides with Organosilanes,Jitan Zhang, Hui Chen, Binjie Wang, Zhanxiang Liu, Yuhong Zhang,* Org. Lett.2015,17, 2768.


5) Rhodium(III)-Catalyzed One-Pot Access to Isoquinolines and Heterocycle-Fused Pyridines in Aqueous Medium through C-H Cleavage,Jitan Zhang, Hongsheng Qian, Zhanxiang Liu, Chunhua Xiong, Yuhong Zhang*, Eur. J. Org. Chem.2014,2014, 8110.


4) Regio-and stereoselective synthesis of highly functionalized vinyl ethers via coiodination of acetylenic ketones, Meihu Xie,* Jitan Zhang, Peng Ning, Zhannan Zhang, Xing Liu, Linbo Wang, Tetrahedron Lett. 2014, 55, 1065.


3) Pd(II)-catalyzed C(sp²)-H carbonylation of biaryl-2-amine: synthesis of phenanthridinones, Zunjun Liang, Jitan Zhan, Zhanxiang Liu, Kai Wang, Yuhong Zhang,* Tetrahedron 2013, 69, 6519.


2) Transition metal-catalyzed C-H bond functionalizations by the use of diverse directing groups, Zhengkai Chen, Binjie Wang,Jitan Zhang, Wenlong Yu, Zhanxiang Liu, Yuhong Zhang,* Org. Chem. Front. (Review), 2015，2, 1107.


1) Synthesis of Benzyl Esters via Functionalization of Multiple C-H Bonds by Palladium Catalysis, Danyang Li, Ming Yu,Jitan Zhang, Zhanxiang Liu, Yuhong Zhang,* Org. Lett. 2015, 17, 5300.

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