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安徽师范大学生命科学学院导师教师师资介绍简介-李明会

本站小编 Free考研考试/2021-04-24


· 姓名:李明会
· 职称:讲师
· 电话:
· 邮箱:liminghui@ahnu.edu.cn

◆ 主要学习工作经历
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· 2011年山东农业大学中药资源与开发专业获理学学士学位
· 2014年中国药科大学中药化学专业获理学硕士学位
· 2018年南京理工大学大学化学工程与技术专业获工学博士学位
· 2018年至今,安徽师范大学生命科学学院工作
◆ 主要社会兼职
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· 中国细胞生物学会会员
· Scientific Report, Journal of Ethnopharmacology, Planta Medica, Evidence-based Complementary and Alternative Medicine等期刊审稿人
◆ 主要研究内容
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· 主要方向为基于代谢组学的细胞代谢调控、靶标发现与功能验证,以及中药及天然药物的作用机制研究
· 安徽省自然科学基金项目,基于小胶质细胞极化研究TSG对大鼠脑缺血再灌注损伤的保护机制(**QH342),2019-2021年,主持
◆ 主要研究成果
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1、代表性论文(20篇以内,*号为通讯作者):
· Li, M.-H.#; Feng, X.#; Chen, C.; Ruan, L.-Y.; Xing, Y.-X.; Chen, L.-Y.; Zhong, G.-J.*; Wang, J.-S.*, Hepatoprotection of Herpetospermum caudigerum Wall. against CCl4-induced liver fibrosis on rats. J. Ethnopharmacol. 2019, 229, 1-14.
· Li, M.-H.; Ruan, L.-Y.; Chen, C.; Xing, Y.-X.; Hong, W.; Du, R.-H.; Wang, J.-S.*, Protective effects of Polygonum multiflorum on ischemic stroke rat model analysed by 1H NMR metabolic profiling. J. Pharm. Biomed. Anal. 2018, 155, 91-103.
· Li, M.-H.#; Du, H.-Z.#; Kong, G.-J.; Liu, L.-B.; Li, X.-X.; Lin, S.-S.; Jia, A.-Q.; Yuan, S.-T.*; Sun, L.*; Wang, J.-S.*, Nuclear Magnetic Resonance-Based Metabolomics Approach to Evaluate the Prevention Effect of Camellia nitidissima Chi on Colitis-Associated Carcinogenesis. Front. Pharmacol. 2017, 8, 447.
· Li, M.-H.; Ruan, L.-Y.; Zhou, J.-W.; Fu, Y.-H.; Jiang, L.; Zhao, H.; Wang, J.-S.*, Metabolic profiling of goldfish (Carassius auratis) after long-term glyphosate-based herbicide exposure. Aquat. Toxicol. 2017, (188), 159-169.
· Li, M.-H.; Xu, H.-D.; Liu, Y.; Chen, T.; Jiang, L.; Fu, Y.-H.; Wang, J.-S.*, Multi-tissue metabolic responses of goldfish (Carassius auratus) exposed to glyphosate-based herbicide. Toxicol. Res. 2016, 5 (4), 1039-1052.
· Li, M.-H.#; Ruan, L.-Y.#; Liu, Y.; Xu, H.-D.; Chen, T.; Fu, Y.-H.; Jiang, L.; Wang, J.-S.*, Insight into biological system responses in goldfish (Carassius auratus) to multiple doses of avermectin exposure by integrated 1H NMR-based metabolomics. Toxicol. Res. 2015, 4 (5), 1374-1388.
· Li, M.-H.; Wang, J.-S.*; Lu, Z.-G.; Wei, D.-D.; Yang, M.-H.; Kong, L.-Y.*, NMR-based metabolomics approach to study the toxicity of lambda-cyhalothrin to goldfish (Carassius auratus). Aquat. Toxicol. 2014, 146, 82-92.
· Ruan, L.-Y.#; Li, M.-H.#; Xing, Y.-X.; Hong, W.; Chen, C.; Chen, J.-F.; Xu, H.; Zhao, W.-L.; Wang, J.-S.*, Hepatotoxicity and hepatoprotection of Polygonum multiflorum Thund as two sides of the same biological coin. J. Ethnopharmacol. 2019, 230, 81-94.
· Xing, Y.-X.#; Li, M.-H.#; Tao, L.; Ruan, L.-Y.; Hong, W.; Chen, C.; Zhao, W.-L.; Xu, H.; Chen, J.-F.; Wang, J.-S.*, Anti-Cancer Effects of Emodin on HepG2 Cells as Revealed by 1H NMR Based Metabolic Profiling. J. Proteome Res. 2018, 17 (5), 1943-1952.
· Feng, X.#; Li, M.-H.#; Xia, J.; Ba, D. J. D.; Ruan, L.-Y.; Xing, Y.-X.; Chen, C.; Wang, J.-S.*; Zhong, G.-J.*, Tibetan Medical Formula Shi-Wei-Gan-Ning-Pill Protects Against Carbon Tetrachloride-Induced Liver Fibrosis–An NMR-Based Metabolic Profiling. Front. Pharmacol. 2018, 9.
· Lu, Z.-G.#; Li, M.-H.#; Wang, J.-S.*; Wei, D.-D.; Liu, Q.-W.; Kong, L.-Y.*, Developmental toxicity and neurotoxicity of two matrine-type alkaloids, matrine and sophocarpine, in zebrafish (Danio rerio) embryos/larvae. Reprod. Toxicol. 2014, 47, 33-41.
· Sun, Q.; Li, M.-H.; Yang, X.; Xu, X.; Wang, J.-S.; Zhang, J.-F.*, Dietary salecan reverts partially the metabolic gene expressions and NMR-based metabolomic profiles from high-fat-diet-induced obese rats. J. Nutr. Biochem. 2017, 47, 53-62.
· Shuna Cui*, Minghui Li, Rabeay Y. A. Hassan, Anna Heintz-Buschart, Junsong Wang*, Ursula Bilitewski*, Inhibition of Respiration of Candida albicans by Small Molecules Increases Phagocytosis Efficacy by Macrophages. mSphere Apr 2020, 5 (2) e00016-20.
· 李明会, 阮玲玉, 赵文龙, 孟辉辉, 汪俊松*. 基于代谢组学/药动学整合策略的多组分中药药效物质基础研究. 世界科学技术-中医药现代化 2018, 20(8): 1471-1475.




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